Research
- Last Updated On :
RESEARCH :
Funded projects
Ongoing
S. No. |
Title of the project |
Name of Principal Investigator |
Funded by (Name of funding agency) |
Duration (years) |
Start year – End year |
Total funds sanctioned (Rs) |
1 |
Centre for Medical Innovation and Enterpreunership |
Alok Thakar |
(AIIMS BioNEST) |
4 |
2020 - Ongoing |
4.75 crore |
2 |
A study on frailty, cognitive dysfunction and associated comorbidities with Hearing loss in Geriatric population |
Kapil Sikka |
ICMR |
3 |
2024-2027 |
30.9 Lakhs |
3 |
Intraglandular Botulinum Toxin BoNT Injection for Postoperative Head and Neck Fistula Healing- A Pilot Study |
Smriti Panda |
Intramural early career grant |
2 |
2024-2026 |
5.85 Lakhs |
4 |
Prevention of Radiotherapy Induced Xerostomia by intraductal administration of N- Acetyl Cysteine in patients with Oropharyngeal malignancies: A Randomized Clinical Trial |
Arvind Kumar Kairo |
ICMR |
4 |
2020-2024 |
36 Lakhs |
5 |
Local application of specific Unani drug for medical management of oral submucosal fibrosis (OSF) a randomized clinical control trial |
Arvind Kumar Kairo |
CCRUM |
2 |
2023-24 |
35 Lakhs |
6 |
Phased pilot study to assess the baseline of serum level of Prestin in healthy individuals and in patients of definite Meniere’s Disease as a biomarker of cochlear outer hair cell functional status |
Dr Prem Sagar |
AIIMS |
|
|
5 Lakhs |
7 |
To evaluate nasal eosinophilic miRNAs as potentially diagnostic, prognostic and predictive biomarkers in allergic rhinitis |
Dr Shuchita Singh |
AIIMS |
2 |
2022-24 |
5 Lakhs |
8 |
Transorbital approach to infratemporal Fossa - A cadaveric exploratory Study |
Dr Anup Singh |
AIIMS |
1 year |
Jan 2024 |
5 Lakhs |
9 |
Exome sequencing and molecular characterization in juvenile nasopharyngeal angiofibroma (COLLOBRATIVE PROJECT) |
HITESH VERMA/ DR BHUPINDER VERMA |
AIIMS |
2 |
2021-23 |
20 Lakhs |
10 |
Development of single-cell derived clonal spheroids as a tool for drug discovery in cancer research with focus on Head and Neck Cancer |
DR R.P.SINGH/ DR HITESH VERMA |
DST |
4 |
2019-23 |
3 Crores |
11 |
Prospective study to evaluate the role of Systemic Bevacizumab therapy in patients with aggressive and complex laryngotracheal and pulmonary recurrent respiratory papillomatosis. |
Dr Rajeev Kumar |
AIIMS Intramural Collaborative Research Project
|
2 |
2021-23 |
20 Lakhs |
12 |
Study to determine the role of mTOR pathway in the pathogenesis of juvenile nasopharyngeal angiofibroma |
Dr Rajeev Kumar |
AIIMS Intramural Research Project |
1 |
2021-23 |
5 Lakhs |
13 |
Phased pilot study to assess baseline serum level of Prestin in healthy individuals and in patients of definite Meniere’s disease and ototoxicity as a biomarker of cochlear outer hair cell functional status |
Dr Prem Sagar |
AIIMS, New Delhi Intramural project, A-832 |
3 |
2020-23 |
4.5 Lakhs |
14 |
Device fabrication and clinical validation of a novel mechanical handheld suction device for tracheostomy tube cleaning: a pilot study |
Dr Prem Sagar (chief guide), Dr Ritu Dudi (PG thesis candidate) |
AIIMS, New Delhi |
2 |
2023-25 |
2 Lakhs |
15 |
Clinical validation of the effectiveness of automated speech therapy for stuttering delivered by digital means |
Shuchita Singh Pachaury |
BIRAC |
2 years 3 months |
2020-22 |
10 Lakhs |
16 |
To determine the efficacy of outpatient antimicrobial therapy (OPAT) with Liposomal amphotericin B in invasive sinonasal mucurmycosis, a randomised controlled trial |
Dr. Poonam Sagar |
Research section, AIIMS, Delhi |
Two years |
2024-2026 |
10 Lakhs |
Completed :
S. No. |
Title of the project |
Name of Principal Investigator |
Funded by (Name of funding agency) |
Duration (years) |
Start year –End year |
Total funds sanctioned (Rs) |
|
Evaluation of factors impacting outcomes of cochlear implants in pediatric population |
Kapil Sikka |
ICMR |
3.5 Years |
2029-2023 |
35.3 Lakhs |
2 |
Sound4All: Re-Engineering High end audiometric devices for robust and affordable audiological testing phase II |
Kapil Sikka |
IGSTC (Indo German Science and Technology Center) |
4 |
2019-2023 |
36 Lakhs |
3 |
An evaluation of HLA, phagocytic function and trace elements in cases of sinusitis, invasive fungal sinusitis and non-invasive fungal sinusitis |
Hitesh Verma |
AIIMS |
4 |
2019-23 |
10 Lakhs |
4 |
ACE-2 receptor expression in sino-nasal mucosa in patients with COVID 19 associated mucormycosis |
Hitesh Verma |
AIIMS |
2 |
2021-23 |
3.7 Lakhs |
Departmental projects (including thesis/dissertations) :
Ongoing
S. No. |
Title of the project |
1 |
A pilot study to assess the effect of intraductal N acetyl cysteine on swallowing and voice outcomes of patients with oropharyngeal cancer undergoing radiotherapy |
2 |
To compare different Cochlear Implantation outcome scores with auditory cortical activity seen on functional near infrared spectroscopy in prelingual profound SNHL patients after Cochlear Implantation |
3 |
Analysis of voice outcomes after radiation or chemo radiation in carcinoma larynx and the effect of N acetyl cysteine on voice parameters |
4 |
Evaluation of respiratory and voice outcomes in patients with unilateral vocal cord palsy post injection laryngoplasty |
5 |
Exome sequencing and molecular characterization in juvenile nasopharyngeal angiofibroma |
6 |
A prospective study to measure the objective, subjective and aesthetic Outcomes in patients undergoing Septorhinoplasty |
7 |
A comparative study to evaluate functional outcomes following tongue reconstruction with radial artery forearm free flap and infrahyoid myocutaneous flap |
8 |
A single institutional prospective audit of type-1 tympanoplasty and evaluation of factors affecting the outcome. |
9 |
to compare post cochlear implant outcome in candidates with and without residual hearing (RH) |
10 |
Descriptive study of the anatomical variations of the superficial temporal artery and the posterior auricular artery in the patients with unilateral microtia and its implications on the surgical outcomes in auricular reconstruction surgery |
11 |
To evaluate prospective auditory cortical activity changes on functional near infrared spectroscopy in prelingual profound snhl patients undergoing cochlear implantation |
12 |
Serum prestin and otolin-1 as markers of cisplatin-induced ototoxicity in cervical cancer patientsThesis |
13 |
Role of Adjuvant Therapy in Early-Stage Oral Cavity Squamous Cell Carcinoma: An Ambispective Analysis |
14 |
Ambispective study to assess Universal Newborn Hearing Screening Program |
15 |
Comparative evaluation of CAD- CAM planning versus traditional free fibula planning in surgical outcomes in mandibular reconstruction-A prospective study |
16 |
Correlation of Depth Of Invasion with Lymph node Metastasis in Laryngeal and Hypopharyngeal carcinoma |
17 |
A prospective study to evaluate role of various frailty screening instruments in predicting surgical complications in geriatric head neck cancer patients. |
18 |
Comparative study evaluating Ex-Vivo US aided deep margin assessment with fresh frozen section analysis in T1-T3 tongue carcinoma: Feasibility study |
19 |
Ambispective study to assess various primary tumour and ipsilateral nodal factors associated with contralateral nodal metastasis in patients with OCSCC |
20 |
Study evaluating the effectiveness of Barbed suture versus Vicryl suture for pharyngeal closure after total laryngectomy in PCF reduction |
21 |
Prospective analysis of predictive factors for tracheal stomal stenosis after total laryngectomy for laryngeal and hypopharyngeal malignancies(2021 -2023, Non funded study) |
22 |
Role of ultrasound in predicting the depth of tumour invasion and lymph node metastasis in early tongue carcinoma.(2017-till date, Non-Funded Study) |
23 |
Evaluation of short term and long-term effects of cochlear implantation on vestibular function |
24 |
A prospective cohort study to evaluate the feasibility and accuracy of fetal vibroacoustic stimulation as a prenatal hearing screening tool |
25 |
Device fabrication and clinical validation of a novel mechanical handheld suction device for tracheostomy tube cleaning: a pilot study |
26 |
Short & Long term effects on vestibular apparatus of cochlear implant |
27 |
A Prospective study to measure the objective, subjective and aesthetic outcomes in patient undergoing Septorhinoplasty |
27 |
Prospective study to correlate rhinomanometry in DNS patients with endoscopy, NOSE score and NCCT PNS study |
28 |
A Randomized Control Trial to compare the outcomes of endoscopic and microscopic stapes surgery |
29 |
Prospective study to evaluate the efficacy of PNN as treatment modality in patient with PAR along with medical management |
30 |
To evaluate poor prognosis factors in laryngotracheal stenosis: An ambispective study |
31 |
Impact of NACT on surgical decision and perioperative outcome in patient with very advanced buccal cancer |
32 |
A randomised control trial on the effectiveness of anti fungal and stetoid nasal douching in allergic fungal rhinosinusitis: a clinical, radiological and biochemical corelation |
33 |
Descriptive study of the anatomical variations of the superficial temporal artery and the posterior auricular artery in the patients with unilateral microtia and its implications on the surgical outcomes in auricular reconstruction surgery |
34 |
Prospective audit of tympanoplasty and evaluation of factors affecting the outcome |
35 |
To assess the outcomes of lateral skull base lesions who have been surgically operated with special reference to quality of life |
36 |
Prospective assessment of auditory and cognitive performance in children undergoing ear surgeries: A comparative study |
37 |
Comparative analysis of qPCR, mRNA ISH and p16 IHC for detection of high risk HPV on fine needle aspirates and core needle biopsies in patients with metastatic squamous cell carcinoma in cervical lymph nodes |
38 |
Role of preoperative nutritional intervention in improving surgical outcome of patients with oral squamous cell carcinoma |
39 |
Effect of intranasal corticosteroids and antihistaminics v/s omalizumab on adenoid hypertrophy |
40 |
Effect of Palatal Morphology on Eustachian Tube Function in Children with Adenoid Hypertrophy: an Observation Study |
41 |
Assessment of pre-cervical (perimarginal and lingual) lymph nodes as first echelon for squamous cell carcinoma of oral cavity |
42 |
Adversity and QOL Post Treatment of Laryngeal and Hypopharyngeal Cancer and Impact of Novel AIMS-IIT-TEP in its Mitigation. |
43 |
Evaluating the effectiveness of Barbed suture versus Vicryl for pharyngeal closure after total laryngectomy in PCF reduction: A Randomised controlled study |
44 |
A Study analysing "Back to Normalcy" in Oral Cavity Cancer Survivors |
45 |
A prospective study to evaluate the role of various frailty screening instruments in predicting surgical complications in geriatric head neck cancer patients. |
46 |
Sentinel lymph node detection in oral squamous cell carcinoma with negative neck: comparison between [99mTc] Sulphur colloid AND [99mTc] DTPA ANTICytokeratin- Collagenous Nanoparticle (DC-Col NP) |
Completed :
S.No. |
Title of the project |
1 |
A Prospective Study to evaluate the impact of Oral Sub mucous Fibrosis (OSMF) on occult and overt lymph nodal metastases in Gingivo-buccal complex carcinomas (GBCC) (T1-T4a) of Oral cavity |
2 |
A prospective study to determine early predictive factors of hypocalcemia in patients undergoing total or completion thyroidectomy |
3 |
Prospective pilot study to assess the effectiveness of novel Forehead Knuckle Tapping method in localisation of better or worse hearing ear as compared to conventional tuning fork testing |
4 |
A prospective pilot study to evaluate the effect of Supraglottoplasty on Tracheomalacia in pediatric patients with Congenital Laryngotracheomalacia |
5 |
An ambispective cohort control study to evaluate the incidence of SARS CoV-2 infection in post Adenoidectomy/Adenotonsillectomy patients |
6 |
Comparison Of Suction Verses Microdissection Method For Harvesting Supporting Cell From Inner Ear |
7 |
Observational study to correlate site of obstruction in OSA with eustachian tube dysfunction and reflux disorders |
8 |
Ambispective study to evaluate the utility of Supraclavicular artery island flap [SCAIF] reconstruction in Head and Neck Cancers |
9 |
A cohort study on determining the effect of preoperative residual hearing on post cochlear implant outcome |
Collaborative projects :
Ongoing
S. No. |
Title of the project |
Collaborating department/institution |
1 |
To evaluate the role of Kit-based Loop-Mediated Isothermal Amplification (TB-LAMP) assay in the diagnosis of Extra-pulmonary tuberculosis (EPTB) |
Medicine Department |
2 |
Analysis of circulating DNA for BRAF (T 1799A) mutation as a futuristic non-invasive tool for diagnosis, prognostication, targeted therapy and folloW-up of papillary thyroid cancer |
Pathology |
3 |
Phase IIb/III Study to determine efficacy of curcumin and Metformin to reduce the incidence of Second Primary tumors of Aero-digestive tract in patients with history of head and neck squamous cell carcinoma |
National Cancer Grid |
4 |
Clinical validation of the effectiveness of automated speech therapy for stuttering delivered by digital means |
BIRAC |
5 |
Effect of Cochlear implantation on middle ear and saccular function |
Collabrative project with AIISH, Mysuru |
6 |
Molecular characterization of olfactory neuroblastomas for classification into prognostically and therapeutically relevant subgroups. |
Dr. Aanchal Kakkar ( Pathology- PI). |
7 |
Evaluation of Machine Learning Techniques including Deep Learning for the Identification of Malignancy in Tissue Samples. |
AIIMS- IIT Delhi Joint Collaborative Funding 019-2021, Dr. Aanchal Kakkar ( Pathology - PI). |
8 |
Inter- institutional program for maternal neonatal and infant science : A translational approach- interdisciplinary group for advanced research on birth outcome |
DBT India initiative ( GARBH- Ini-Phase II) |
9 |
A study on the effect of genetic manipulation on mammalian inner ear cells |
Dept of Biochemistry |
10 |
Exome sequencing and molecular characterization in juvenile nasopharyngeal angiofibroma |
Biotechnology/ AIIMS |
11 |
Evaluation of specific molecular alterations and tumor immune microenvironment for detection of clinically actionable targets in high grade salivary gland carcinomas |
ICMR Funded, Department of Pathology |
12 |
The SWOAR trial: A phase III trial evaluating dysphagia-aspiration related structures & submandibular gland sparing Intensity modulated radiotherapy (SWOAR-IMRT) versus standard IMRT in Head and neck squamous cell carcinoma |
Department of Radiotherapy |
13 |
The tumour immune microenvironment of follicular cell -derived thyroid carcinomas across different grades utilizing gene expression and spatial proteomic profiling |
Department of Pathology |
14 |
Role of celecoxib in reducing cognitive impairment in patients receiving definitive chemoradiation for head and neck carcinoma: A phase II randomized placebo controlled trial |
Department of Medical Oncology |
15 |
Potentially malignant lesion atlas project: Validating the efficacy of a novel, Point-of -care diagnostics and developing an integrated multidimensional, prognostic nomogram |
ICMR funded, Department of Preventive Oncology, NCI AIIMS |
16 |
Comparative analysis of qPCR, mRNA ISH and p16 IHC for detection of high risk HPV on fine needle aspirates and core needle biopsies in patients with metastatic squamous cell carcinoma in cervical lymph nodes |
Collaborative Intramural, AIIMS |
17 |
A Phase III , Randomized Controlled Study of Utility of Pectoralis Major Myofascial Flap in Reducing Pharyngocutaneous Fistula Rates After Salvage Total Laryngectomy. |
TMH |
18 |
A randomised, sham controlled, double blind study to evaluate the efficacy of and safety of intra-thecal OAV101 in patients with later onset type-2 spinal muscular atrophy who are ≥ 2 to < 18 years of age, treatment naive, sitting, and never ambulatory. |
A phase 3 Clinical trial (STEER) by Novartis Pharmaceuticals. ClinicalTrials.gov Identifier: NCT05089656. |
19 |
Prevalence and pattern of traumatic dental injury in children and adolescents with severe to profound hearing impairment reporting to a tertiary care centre in North India |
Pediatric Dentistry, CDER, AIIMS, New Delhi |
20 |
Comparison of pulsed radio-frequency versus conventional radio-frequency in secondary glossopharyngeal neuralgia: a randomised controlled trial |
Department of Anaesthesiology, AIIMS, New Delhi |
21 |
Perioperative anaesthetic management of paediatric congenital laryngomalacia- A retrospective study |
Department of Anaesthesiology, AIIMS, New Delhi |
22 |
A Phase II trial of Pentoxiphylline and alpha tocopherol (PAT) in prevention of radiation induced dysphagia in head and neck squamous cell carcinoma |
Radio-therapy |
23 |
A Phase III prospective randomised trial comparing dysphagia-aspiration related structures & submandibular gland sparing Intensity modulated radiotherapy (SWOAR-IMRT) versus standard IMRT (s-IMRT) paring in locally advanced oropharyngeal and laryngeal carcinomas |
Radio-therapy |
24 |
Ultrasonographic assessment of tonsillar volume in children undergoing tonsillectomy : a predictor of post operative morbidity |
Anaesthesiology |
Complete
S. No. |
Title of the project |
Collaborating department/institution |
|
To Understand the Biochemical and Molecular Basis of Mucormycosis in COVID-19 Patients |
Dept of Biotechnology |
2 |
Evaluation of genetic profile of olfactory neuroblastoma |
Department of Pathology |
3 |
Comparison between kit based and in-house preparation of Tc -99m Ubiquicidin |
Department of Nuclear Medicine |
4 |
Utility of 99m Tc- Ubiquicidin scintigraphy in diagnosis of sinonasal mucormycosis |
Department of Nuclear Medicine |
5 |
Utility of Ga - 68 - NOTA- UBI in infectious and non- infectious lesions |
Department of Nuclear Medicine |
6 |
A phase II study of EMF (Erlotinib+ Methotrexate+ Celecoxib) in platinum refractory recurrent /metastatic head neck squamous cell carcinoma |
Department of Medical Oncology |
7 |
Assessment of Oral Microbiome and its significance in upper aerodigestive tract cancers |
Department of Medical Oncology |
8 |
A cohort study to assess the feasibility of WHO ICOPE approach in tertiary health centres |
Department of Geriatrics, AIIMS, New Delhi |
9 |
A longitudinal Survey to assess Patient Satisfaction for Nurse Initiated Follow Up Tele-Consultation among patients discharged from a selected tertiary care hospital |
Nursing department |
10 |
An OMR sheet based feed-back survey on in-patient satisfaction regarding various hospital services in a selected tertiary care hospital |
Nursing department |