Research
- Last Updated On :
Funded Research Projects :-
|
S. No. |
Title of the project |
Name of Principal Investigator |
Funded by (Name of funding agency) |
Duration (years) |
Start year |
End year |
Total funds sanctioned (Rs) |
| 1 |
A study on frailty, cognitive dysfunction and associated comorbidities with Hearing loss in Geriatric population |
Kapil Sikka
|
ICMR |
3 |
2024 |
2027 |
30,90,000 |
| 2 |
To conduct the pre compliance and clinical validation of implantable and diagnostic devices (Otorhinolaryngology, Opthalmics, and Orthopedic) |
Kapil Sikka |
ICMR |
5 |
2024 |
2029 |
14,95,00,000 |
| 3 |
Community based model for early detection speech and language training of hearing impaired children in four regions in India Mixed methods Implementation study |
Chirom Amit Singh |
ICMR |
3 |
2025 |
2028 |
7,78,75,869 |
| 4 |
Comparative analysis of qPCR, mRNA ISH and p16 IHC for detection of high risk HPV on fine needle aspirates and core needle biopsies in patients with metastatic squamous cell carcinoma in cervical lymph nodes |
Chirom Amit Singh |
AIIMS Intramural project |
2 |
2024 |
2026 |
2,00,000 |
| 5 |
A Pilot Study of Speech Therapy Software to Teach Speech to Children with Severe and Profound Congenital Sensorineural Hearing Loss |
Arvind Kumar Kairo |
ICMR |
1 |
2025 |
2026 |
30,00,000 |
| 6 |
Local application of specific Unani drug for medical management of Oral submucous fibrosis (OSF): A randomized controlled clinical trial |
Arvind Kumar Kairo |
CCRUM, Ministry Of Ayush |
2 |
2026 |
2027 |
34,64,000 |
| 7 |
Device fabrication and clinical validation of a novel mechanical handheld suction device for tracheostomy tube cleaning: a pilot study |
Dr Prem Sagar (chief guide), Dr Ritu Dudi (PG thesis candidate) |
AIIMS Intramural project, A-832 |
2 |
2023 |
2025 |
2,00,000 |
| 8 |
A randomized controlled pilot study to evaluate the effect of systemic omalizumab as compared to that of nasal corticosteroid & antihistaminic on adenoid hypertrophy in symptomatic paediatric patients |
Dr Prem Sagar (chief guide), Dr Manpreet (PG thesis candidate) |
AIIMS Intramural project |
2 |
2024 |
2026 |
2,00,000 |
| 9 |
A Phase IIb/III study to determine efficacy of Curcumin and Metformin to reduce the incidence of second primary tumors of aero-digestive tract in patients with history of head and neck squamous cell carcinoma |
Dr Rajeev Kumar (Site PI) |
NCG |
6years |
2020 |
2026 |
4,20,00,000 |
| 10 |
Prospective study to evaluate the role of Systemic Bevacizumab therapy in patients with aggressive and complex laryngotracheal and pulmonary recurrent respiratory papillomatosis.
|
Dr Rajeev Kumar |
AIIMS Intramural Collaborative Research Project
|
3 |
2021 |
2026 |
20,00,000 |
| 11 |
Study to determine the role of mTOR pathway in the pathogenesis of juvenile nasopharyngeal angiofibroma
|
Dr Rajeev Kumar |
AIIMS Intramural Research Project
|
3 |
2021 |
2025 |
5,00,000 |
| 12 |
Intraglandular botulinum toxin for postoperative head and neck fistula healing : A pilot study (AC-1010) |
Dr. Smriti Panda |
AIIMS- Intramural |
2 |
2024 |
2026 |
5,85,000 |
| 13 |
Acute and Long-Term Impact of Head and Neck Cancer Treatment on Autonomic Function (IIRPSG-2024-01-02559) |
Dr. Smriti Panda |
ICMR- Extramural Small Grant |
3 |
2025 |
2028 |
84,45,837.60 |
| 14 |
Artificial intelligence (AI)-guided intraoperative identification of parathyroid glands during thyroid surgery (AIU-01) |
Dr. Smriti Panda |
AIIMS-IITD-UCL Trilateral Seed Grant |
2 |
2025 |
2027 |
57,06,560 |
| 15 |
Evaluation of Molecular Landscape of Loco-regionally Recurrent Head and Neck Squamous Cell Carcinoma: Preliminary Study to Guide Personalized Treatment (A-1109) |
Dr. Smriti Panda |
NCI-AIIMS Intramural funding |
2 |
2026 |
2028 |
10,00,000 |
| 16 |
To determine the efficacy of outpatient antimicrobial therapy (OPAT) with Liposomal amphotericin B in invasive sinonasal mucurmycosis, a randomised controlled trial |
Dr. Poonam Sagar |
AIIMS- Intramural |
2 |
2024 |
2026 |
10,00,000 |
| 17 |
Effect of Expiratory Muscle Strength Training (EMST) on Dysphagia and Aspiration Prevention in Post- Glossectomy Patients: A Randomized Controlled Trial |
Dr. Manish Verma
|
AIIMS- Intramural (A-1107) |
2 |
2025 |
2027 |
4,55,000 |
| 18 |
Study of the development of radioresistance mechanism in oral cancer via single-cell profiling of patient-derived tumor models. |
Dr Hitesh Verma (Site PI) |
ICMR |
2years |
2024 |
2026 |
52,36,565 |
| 19 |
Molecular Basis of Pathogenesis in HPV-driven Recurrent Respiratory Papillomatosis: Non-coding RNA Discovery, Validation, and Mechanistic Insights |
Dr Hitesh Verma |
AIIMS Intramural Collaborative Research Project
|
2 |
2026 |
2028 |
20,00,000 |
| 20 |
Molecular detection of human papilloma virus DNA in premalignant lesions of oral cavity and Oropharynx in Northern population of India |
Dr. Manaswita Roy |
AIIMS, Delhi |
2 years |
2026 |
2028 |
10,00,000 |
| 21 |
Investigating Pathophysiologic Mechanisms and Biomarkers in Meniere’s Disease: A Multi-Objective Study |
Dr Riyaz Mir Ahmad, Dr Anup Singh |
AIIMS Interdisciplinary Collaborative Intramural Research Project |
2 Years |
2024 |
2026 |
20,00,000 |
Completed Projects
|
S. No. |
Title of the project |
Name of Principal Investigator |
Funded by (Name of funding agency) |
Duration (years) |
Start year |
End year |
Total funds sanctioned (Rs) |
| 1 |
Transorbital approach to infratemporal Fossa - A cadaveric exploratory Study |
Anup Singh |
AIIMS Delhi-Intramural |
2 years |
2024 |
2026 |
4,43,500 |
Departmental projects (including thesis/dissertations)
Ongoing
|
S. No |
Title of the project |
| 1 |
A Phase 2 Open-label Randomised Controlled Trial Comparing Modified TPF with Docetaxel-Platinum Regimen as Neoadjuvant Chemotherapy in Locally Advanced Resectable Oral Cavity Cancer (NeoORAL study). |
| 2 |
A prospective study to evaluate role of various frailty screening instruments in predicting surgical complications in geriatric head neck cancer patients. |
| 3 |
A quasi-experimental clinical study to evaluate the role of oral sirolimus in volume and stage reduction of nasopharyngeal angiofibroma |
| 4 |
A Randomised Controlled Pilot Study to evaluate the effect of systemic Omalizumab as compared to that of Nasal Corticosteroids & Antihistamines on Adenoid Hypertrophy in Symptomatic Paediatric Patients |
| 5 |
A Randomized Control Trial to compare the outcomes of endoscopic and microscopic stapes surgery |
| 6 |
Acute and long term impact of head and neck cancer treatment on autonomic function |
| 7 |
Adjuvant Methotrexate for poor chemo-responders in localized resectable Oral Cavity Carcinoma- a Double Blind Placebo Controlled phase 3 Randomised Controlled Trial (Post-ORAL trial). |
| 8 |
Aggressiveness of Head and Neck Paragangliomas and mitochondrial superoxide production : An observational prospective study |
| 9 |
An RCT to compare the recurrence in patients receiving intra Hg nasal steroids versus intranasal and oral steroids in CRSwNP patients after FESS |
| 10 |
Analysis of the effect of Intra Operative Switch On (IOSO) of cochlear implant as compared to Delayed Switch On of cochlear implant on electrical impedance measurement and auditory skills development in paediatric patients with congenital profound idiopathic non-syndromic sensorineural hearing loss |
| 11 |
Assessing quality of life and surgical outcomes : A comparison of robotic and open thyroidectomy in patients undergoing thyroidectomy |
| 12 |
Clinical and pathological predictors of occult metastasis in early to intermediate stage gingivobuccal squamous cell carcinoma (T1,T2 and T3) of Oral Cavity: A PROSPECTIVE STUDY |
| 13 |
Comparative Analysis of qPCR, mRNA ISH, p16 IHC for detection of high risk HPV on FNA and Core Needle Biopsies in patients with Metastatic SCC in Cervical Lymph Nodes |
| 14 |
Comparative evaluation of CAD-CAM planning versus free fibula planning in surgical outcomes in mandibular reconstruction - A prospective study |
| 15 |
Comparative study evaluating Ex-Vivo US aided deep margin assessment with fresh frozen section analysis in T1-T3 tongue carcinoma: Feasibility study |
| 16 |
Comparing Ex-Vivo Ultrasound aided and Frozen section analysis of deep margins with Final Histopathology in T1-T4 Carcinoma Tongue: A Prospective Study |
| 17 |
Comparison of post operative complication with calibre of Superficial Temporal Artery in patients with unilateral microtia |
| 18 |
Correlation of MRI predicted resection volume with actual volume and percentage tongue volume loss and its impact on speech and swallowing after compartmental glossectomy for T2/T3 oral tongue carcinoma reconstructed with nasolabial flap |
| 19 |
Defining management protocol of Osteoradionecrosis -An Ambispective Analysis. |
| 20 |
Device fabrication and clinical validation of a novel mechanical handheld suction device for tracheostomy tube cleaning: a pilot study |
| 21 |
Effect of embolization on endoscopic excision of early stage JNA: randomized control study |
| 22 |
Effect of Gastric reflux on hearing status in Obstructive Sleep Apnea |
| 23 |
Effect of Levatinib in reducing the size of Thyroid Cancers which are invading surrounding vital structures |
| 24 |
Effect of Maxillary Morphology on Eustachian Tube Function in children with Adenoid Hypertrophy : An Observation Study |
| 25 |
Impact of NACT on surgical decision and perioperative outcomes in patients with very advanced buccal cancer |
| 26 |
Impact of sarcopenia on oncological outcomes in oral cavity squamous cell carcinoma patients undergoing surgery - An Ambispectrive Study |
| 27 |
Impact of surgical manipulation of tumor on Circulating Tumor Cell (CTC) Kinetics in oral cavity squamous cell carcinoma |
| 28 |
Impact of Wendler’s Glottoplasty and Voice feminisation surgery in quality of life in transgender (Male to Female) women |
| 29 |
Longitudinal analysis of survival and quality of life in patients of sinonasal tumours |
| 30 |
Negative versus neutral drainage systems in patients following head and neck surgery- A randomized control study |
| 31 |
Outcomes of patients treated for Lateral Skull Base Tumors with special reference to quality of life |
| 32 |
Outcomes of Type 1 - Tympanoplasty and assessment of factors affecting the outcome |
| 33 |
Predictors of clinical outcomes in Adenoid Cystic Carcinoma in Head and Neck : An Ambispectrive analysis |
| 34 |
Prospective assessment of auditory and cognitive performances in children undergoing ear surgeries : A Prospective study |
| 35 |
Prospective Study on outcomes of cholesteatoma surgery in a tertiary care center |
| 36 |
Role of preoperative nutritional intervention in improving surgical outcomes in patients with Oral Squamous Cell Carcinoma : A randomised controlled Trial |
| 37 |
Sentinel Lymph Node Detection in Oral Squamous Cell Carcinoma with negative neck : comparison between [99mTc] Sulphur colloid and [99mTc] DTPA anti Cytokeratin Collagenous Nanoparticle (DC-Col NP) |
| 38 |
Surgical Outcomes in Compartmental Glossectomy and Standard wide margin excision in T2-T3 Oral Tongue Squamous cell Carcinoma - A Randomised Control Trial |
| 39 |
The impact of Single vs Dual Venous Anastomosis on Free-Flap Viability- an RCT. |
| 40 |
To assess the DOI in laryngeal & hypopharyngeal carcinoma and correlate results with nodal metastasis |
| 41 |
To evaluate the role of debridement vs medical management in chronic invasive fungal rhinosinusitis - a randomised control pilot study |
| 42 |
To study the efficacy of Posterior Nasal Neurectomy as treatment modality in patients with Persistent Moderate to Severe allergic rhinitis along with medical management. |
| 43 |
A prospective cohort study on incidence and characteristics of tinnitus in Patients with otosclerosis and the impact of surgical intervention |
Completed
|
S.No |
Title of the project |
| 1 |
Ambispective cohort study to evaluate the effect of Supraglottoplasty on Tracheomalacia in pediatric patients with Congenital Laryngotracheomalacia (CTRI/2023/06/054248) |
| 2 |
Study evaluating the effectiveness of Barbed suture versus Vicryl suture for pharyngeal closure after total laryngectomy in PCF reduction |
| 3 |
Ambispective study to assess various primary tumour and ipsilateral nodal factors associated with contralateral nodal metastasis in patients with OCSCC |
| 4 |
Ambispective study to evaluate the utility of Supraclavicular artery island flap [SCAIF] reconstruction in Head and Neck Cancers |
| 5 |
To evaluate poor prognostic factors in laryngotracheal stenosis: An Ambisective study |
| 6 |
Descriptive study of the anatomical variation of the suerficial temporal artery and posterior auricular artey in the patient wit unilateral microtia and its implication on the surgical outcomes in auricular reconstrion surgery. |
| 7 |
To evaluate prospective auditory cortical activity changes on functional near intrared spectroscope in prelingual profound SNHL patients undergoing cochlear implantation. |
| 8 |
Retrospective study- Long term outcomes of cochlear implantation in Inner Ear Malformation- surgical and auditory perspective. (Non- Funded) |
| 9 |
Measles virus in otosclerosis pathogenesis- prospective study |
| 10 |
A randomized control trial on the effectiveness of antifungal and steroid nasal douching in allergic fungal rhinosinusitis: a clinical, radiological and biochemical co-relation |
| 11 |
Role of Adjuvant Radiation Therapy in Early Stage oral cavity squamous cell carcinoma - an ambispectrive analysis |
| 12 |
A Study analysing “Back to Normalcy” in oral cavity cancer survivors |
| 13 |
DNS patients improvement with Septoplasty using Rhinomanometry |
| 14 |
Ambispective study to assess universal newborn hearing screening program |
| 15 |
A prospective cohort study to evaluate the feasibility and accuracy of fetal vibroacoustic stimulation as a prenatal hearing screening tool |
Collaborative projects
Ongoing
|
S. No |
Title of the project |
Collaborating department/institution |
| 1 |
Long-term follow up of patients with spinal muscular atrophy treated with OAV101 IT or OAV101 IV in clinical trials |
A phase 3 Clinical trial (STEER) by Novartis Pharmaceuticals. Department of Pediatrics |
| 2 |
Comparison of pulsed radio-frequency versus conventional radio-frequency in secondary glossopharyngeal neuralgia: a randomised controlled trial |
Department of Anaesthesiology, AIIMS, New Delhi |
| 3 |
Perioperative anaesthetic management of paediatric congenital laryngomalacia- A retrospective study |
Department of Anaesthesiology, AIIMS, New Delhi |
| 4 |
To assess the efficacy and safety of oral Sirolimus in vascular malformation: A prospective pilot assessor-blinded interventional study |
Department of Dermatology, AIIMS, New Delhi |
| 5 |
Genetic signatures of Cisplatin-induced hearing loss in pediatric cancer survivors |
Department of Pediatric Surgery, AIIMS, New Delhi |
| 6 |
Study to determine the role of mTOR pathway in the pathogenesis of juvenile nasopharyngeal angiofibroma |
Department of Pathology, AIIMS, New Delhi |
| 7 |
Intra-nasal steroids alone and in combination with Levocetirizine , and/or Montelukast for moderate to severe allergic rhinitis in children: a randomized controlled trial |
Department of Pediatrics, New Delhi |
| 8 |
Disease phenotypes in neonates with severe bronchopulmonary dysplasia: a descriptive cohort study |
Department of Pediatrics, Division of Neonatology, AIIMS, New Delhi |
| 9 |
Treatment strategies and clinical outcomes in adult patients with mucormycosis: an ambispective observational cohort study. |
Department of Medicine, AIIMS, New Delhi |
| 10 |
Prevalence and pattern of vestibular dysfunction in vestibular schwannoma patients undergoing resection at a tertiary care hospital |
Department of Physiology, AIIMS, New Delhi |
| 11 |
Serum Prestin as an Early Biomarker of Cisplatin-Induced Ototoxicity in Paediatric Solid Tumours |
Department of Pediatric Surgery, AIIMS, New Delhi |
| 12 |
Comparative evaluation of vestibular functions using subjective visual vertical in adult patients with chronic otitis media |
Govt Medical College, Jammu |
| 13 |
Evaluation of specific molecular alterations and tumor immune microenvironment for detection of clinically actionable targets in high grade salivary gland carcinomas |
ICMR Funded, Department of Pathology |
| 14 |
The tumour immune microenvironment of follicular cell -derived thyroid carcinomas across different grades utilizing gene expression and spatial proteomic profiling |
DST-SERB Funded, Department of Pathology |
| 15 |
Potentially malignant lesion atlas project: Validating the efficacy of a novel, Point-of -care diagnostics and developing an integrated multidimensional, prognostic nomogram |
ICMR funded, Department of Preventive Oncology, NCI AIIMS |
| 16 |
Assessment of PRKD and SS18 gene alterations in low grade salivary gland adenocarcinomas |
AIIMS Intramural Undergraduate Research grant (2024-2025) |
| 17 |
To evaluate the role of multiparametric MRI and shear wave elastography in evaluation of salivary gland neoplasms |
Department of Radiology |
| 18 |
The HYPCON Trial 2: A phase II randomized study evaluating hypo-fractionated versus conventional adjuvant concurrent chemoradiation therapy in head and neck malignancies |
Department of Radiotherapy |
| 19 |
R2TP expression and its significance in thyroid cancer |
Department of Biochemistry |
| 20 |
Assessment of the tumor immune microenvironment in salivary duct carcinoma |
Dept. of Pathology
|
| 21 |
A phase 2 open label randomized controlled trial comparing modified TPF with Docetaxel -Platinum regimen as neo-adjuvant chemotherapy in locally advanced resectable oral cavity cancer- NeoOral Study |
Dept. of Medical Oncology |
| 22 |
Adjuvant methotrexate for poor chemo-responders in localized resectable oral cavity carcinoma - a double-blind placebo-controlled phase 3 randomized trial (Post- ORAL study) |
Dept. of Medical Oncology
|
| 23 |
Study comparing hypofractionated radiotherapy versus conventional chemoradiation in Elderly patients with locally advanced head and neck squamous cell carcinoma (SHINE trial): A phase II open label randomized controlled trial |
Department of Radiation Oncology
|
| 24 |
Study of potential diagnostic and prognostic biomarkers for precursor lesions of oral squamous cell carcinoma |
Department of Pathology
|
| 25 |
Study of the development of radioresistance mechanism in oral cancer via single-cell profiling of patient-derived tumor models. |
SCSM, JNU |
| 26 |
Molecular Basis of Pathogenesis in HPV-driven Recurrent Respiratory Papillomatosis: Non-coding RNA Discovery, Validation, and Mechanistic Insights |
Biotechnology, AIIMS |
| 27 |
Investigating the Differential Gene Expression of Hsp70 Family Proteins Across Various Stages of Oral Squamous Cell Carcinoma |
Biochemistry, AIIMS |
| 28 |
GARBH-Ini, Inter-Institutional Program for Maternal,Neonatal and Infant sciences: A translational approach- interdisciplinary Group for Advanced Research on BirtH outcome- DBT India Initiative (GARBH-Ini- Phase II) |
Translational Health Science And Technology Institute |
| 29 |
National Centre for Assistive Health Technology, AIIMS, New Delhi, national centre for research, development, innovation, training, promotion and dissemination of Assistive |
Department of Cardiology, AIIMS, New Delhi |
| 30 |
Community-based Operational research on improving health and social care services in PWD (Vision and other disabilities) in Delhi. |
Community Ophthalmology at RPC Ophthalmic Sciences, AIIMS, New Delhi |
| 31 |
To investigate the potential of Atohl Knock in approach using CRISPR mediated adenovirus for hair cell regeneration in mouse cell line derived from the organ of corti. |
Department of Biochemistry, AIIMS, New Delhi |
| 32 |
Restoring Hearing Loss via CRISPR-based adenoviral Integration of SLC26A4 at a Genomic safe Harbor Locus |
Department of Biochemistry, AIIMS, New Delhi |
| 33 |
A study on the effect of genetic manipulation on mammalian inner ear cells |
Department of Biochemistry, AIIMS, New Delhi |
| 34 |
Strengthening Healthcare National Programs with AI and making healthcare accessible: Oral cancer screening |
in collaboration with Centre for Dental Education and Research, AIIMS
|
| 35 |
Histopathology based artificial intelligence enabled prediction of malignant transformation, lesion progression and patient survival in Oral potentially malignant disorders |
in collaboration with Centre for Dental Education and Research, AIIMS
|
| 36 |
Ultrasonographic assessment of tonsillar volume in children undergoing tonsillectomy: a predictor of post-operative morbidity |
Department of Anaesthesiology |
| 37 |
A Phase III prospective randomised trial comparing dysphagia-aspiration related structures & submandibular gland sparing Intensity modulated radiotherapy (SWOARIMRT) versus standard IMRT (s-IMRT) paring in locally advanced oropharyngeal and laryngeal carcinomas |
Department of Radiotherapy |
| 38 |
A Phase II trial of Pentoxiphylline and alpha tocopherol (PAT) in prevention of radiation induced dysphagia in head and neck squamous cell carcinoma |
Department of Radiotherapy
|
| 39 |
creation of educational activities and follow-up of HPV related malignancies |
Global partner in the collaborative effort of UCLA Global Health Seed Grant Program concerning HPV related cancers to assess physician, trainee, and medical student knowledge and attitudes regarding HPV and HPV vaccination |
| 40 |
To evaluate nasal mucosal miRNAs as potential diagnostic, prognostic and predictive bio-markers in vitamin D deficient allergic rhinitis |
Intra-mural project under ICMR |
Complete
|
S. No. |
Title of the project |
Collaborating department/institution |
| 1 |
To evaluate the role of Kit-based Loop-Mediated Isothermal Amplification (TB-LAMP) assay in the diagnosis of Extra-pulmonary tuberculosis (EPTB) |
AIIMS Medicine department |
| 2 |
Analysis of circulating DNA for BRAF (T 1799A) mutation as a futuristic non-invasive tool for diagnosis, prognostication, targeted therapy and follo-up of papillary thyroid cancer |
ICMR, AIIMS Pathology |
| 3 |
A randomised, sham controlled, double blind study to evaluate the efficacy of and safety of intra-thecal OAV101 in patients with later onset type-2 spinal muscular atrophy who are ≥ 2 to < 18 years of age, treatment naive, sitting, and never ambulatory. |
A phase 3 Clinical trial (STEER) by Novartis Pharmaceuticals. ClinicalTrials.gov Identifier: NCT05089656. |
| 4 |
Evaluation of genetic profile of olfactory neuroblastoma |
Department of Pathology |
| 5 |
Diagnostic Potential of Magnetic Nanoparticle Quantum dot coupled immunofluorescence assay (MNQDCINFA) in non-tobacco HPV induced head and neck cancer. |
Department of Anatomy |
| 6 |
Clinico-Epidemiological spectrum And factors affecting prognosis of Mucormycosis |
Department of Medicine |
| 7 |
Study of host tissue reactions in invasive fungal sinusitis |
Department of Pathology |
| 8 |
Molecular Basis of Mucormycosis infection |
Dept of Biotechnology |
