Research
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Research Work
The list of ongoing funded research projects with the departmental faculty as principal investigators (PI)/ Co-PI are given below:
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Development of a Multiplexed Nanostring Based Locus Copy Number and mRNA Expression Evaluation Assay for Classification of Wilms Tumor for Diagnosis, Prognosis and Treatment Planning (Dr. Venkateshwaran K Iyer, ICMR)
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Molecular characterization of Endometrial Cancer and its correlation with Clinicopathological Features (Dr. Sandeep Mathur, AIIMS Research Section)
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To investigate metabolic perturbations in Endometrial Cancer by targeted transcriptomics approach in an Indian cohort (Dr. Sandeep Mathur, ICMR)
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Immunohistochemical characterization of four common viruses in a clinically suspected cases of viral myocarditis (Dr. Ruma Ray and Dr. Sudheer Arava, AIIMS Research Section)
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Clinicopathological correlation and amyloid subtyping in cases of cardiac amyloidosis: AN observational study (Dr. Ruma Ray and Dr. Sudheer Arava, DBT-ICMR)
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Sudden cardiac death in young: An autopsy and molecular study to identify the cause Dr. Ruma Ray and Dr. Sudheer Arava, ICMR)
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To evaluate the genetic association in undiagnosed idiopathic cardiomyopathy patients (Dr. Ruma Ray and Dr. Sudheer Arava, ICMR)
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Comparison of various diagnostic modalities for identification of refractory celiac disease in a cohort of patients with celiac disease unresponsive to gluten -free diet (Dr. Prasenjit Das, ICMR)
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Explainable Deep Learning for Automated Evaluation & Grading of Duodenal Biopsies (Dr. Prasenjit Das, AIIMS-IIT)
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A multi-centre study on determination of prevalence of incidental gall bladder carcinoma in India (Dr. Prasenjit Das, NCDIR-ICMR)
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Correlation of Immunologic Milieu and PD-L1 in Non-Small Cell Lung Carcinoma (Dr. Deepali Jain, AIIMS Research Section)
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Study of HPV association in Sino-nasal epithelial tumors (Dr. Deepali Jain, AIIMS Research Section)
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Immunomodulators in small cell lung cancer: basis for implementation of cancer immunotherapy (Dr. Deepali Jain, DST-SERB)
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Dissecting the molecular pathogenetic mechanisms of covid-19 by RNA-sequencing of lung tissue from deceased patients (Dr. Deepali Jain, AIIMS Research Section)
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Molecular sub-typing of small cell lung carcinoma (SCLC) to unravel the biological heterogeneity in clinical settings (Dr. Deepali Jain, ICMR)
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Tumor mutation burden in advanced non-small cell lung carcinomas: Implications for planning treatment strategies (Dr. Deepali Jain, DST-SERB)
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PDL1 Immunohistochemistry in Lung Carcinoma (Dr. Deepali Jain, AIIMS Research Section)
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Study of Urinary Exosome as a Predictive biomarker for podocytic injury in childhood idiopathic nephrotic syndrome (Dr. Geetika Singh, DBT)
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The Genetic Landscape of Alport Syndrome in India with Phenotypic Correlation (Dr. Geetika Singh, ICMR)
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Development of Labyrinth based mechanical and fast isolation technique for identifying circulating tumor cells of colorectal carcinomas for metastasis evaluation (Dr. Asit Ranjan Mridha, DHR-ICMR)
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Utility of Artificial Intelligence in differentiating Non-invasive Follicular Thyroid Neoplasm with Papillary like Nuclear Features from other follicular-patterned thyroid benign and malignant lesions (Dr Shipra Agarwal, DBT)
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Normal superior and inferior parathyroid glands: Molecularly similar or dissimilar? (Dr Shipra Agarwal, AIIMS Research Section)
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Analysis of circulating DNA for BRAF(T1799A) mutation as a futuristic non-invasive tool for diagnosis of papillary thyroid cancer (Dr Shipra Agarwal, ICMR)
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Identification of novel molecular subtypes of prostate cancer as potential therapeutic targets for immunotherapy (Dr. Seema Kaushal, ICMR)
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To evaluate the role of R2TP Complex as a novel regulator of PI3K/Akt/mTOR and AR signalling pathway in prostate cancer (Dr. Seema Kaushal, DHR-ICMR)
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Evaluation of microsatellite instability (MSI) and PDL1 expression in molecular subtypes of upper and lower tract urothelial carcinoma (Dr. Seema Kaushal, AIIMS Research Section)
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Evaluation of Artificial Intelligence as a Diagnostic Tool for Automated Detection and Grading of Colorectal Cancer (Dr Rajni Yadav, AIIMS-IIT)
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Histopathological and Molecular Classification of Gastrointestinal Stromal Tumors (Dr Rajni Yadav, AIIMS Research Section)
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Clinical, Pathological and Genetic Characterization of Neonatal Cholestasis (Dr Rajni Yadav, DHR-ICMR)
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To Evaluate The Role Of Cmyc, Bcl2, Bcl6 And Epstein Barr Virus On Survival In Patients With Refractory/Relapsed Primary Diffuse Large B Cell Lymphoma: An Ambispective Study (Dr Saumyaranjan Mallick, DST)
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To Evaluate The Role Of Microenvironment Clonality Assay And 9p24 Alteration In Diagnosis And Prognostication Of Refractory Hodgkin’s Lymphoma (Dr. Saumyaranjan Mallick, DST)
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To Evaluate The Molecular Subtypes Of Peripheral T Cell Lymphomas (Dr. Saumyaranjan Mallick, AIIMS Research Section)
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MUC1 Pulsed DC-derived exosomes for cancer immunotherapy (Dr. Adarsh Barwad, DBT)
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Molecular analysis of Giant Cell Tumour of Bone and its correlation with response to Zoledronic acid treatment (Dr. Adarsh Barwad, AIIMS Research Section)
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Nanotechnological intervention in dental and bone implants: Tailoring smart, multifunctional interface towards improved osseointegrative and anti-bacterial properties (Dr. Adarsh Barwad, DBT)
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Development Of Novel Nanocarrier Based Oral Formulation of AmB as A Therapeutic Alternative (Dr. AK Dinda and Dr Adarsh Barwad, DBT)
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Affordable, Effective Personalised Point-Of-Use Wound Care Patches at Patient Bedside for Large Asymmetric Burn Wound (Dr. AK Dinda and Dr. Adarsh Barwad, DST-SERB)
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Development Of Minimal Invasive Novel Injectable Hydrogel and Nano-Carrier-Hybrid System for Localised Targeted Cancer Therapy (Dr. AK Dinda and Dr. Adarsh Barwad, DHR-ICMR)
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NIRMANN 3D Novel Minimally Invasive Implants for Reconstructive Surgery Using Material Providing Mechanical Instruction and Prepared By 3D Printing (Dr. AK Dinda and Dr. Adarsh Barwad, DBT)
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Evaluation of EGFR mutations, HPV status and PD-L1 expression in pathogenesis of sinonasal squamous neoplasms (Dr. Aanchal Kakkar, AIIMS Research Section)
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Molecular characterization of olfactory neuroblastomas for classification into prognostically and therapeutically relevant subgroups (Dr. Aanchal Kakkar, DST-SERB)
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Molecular characterization of salivary gland carcinomas: A comparative study between AIIMS and North-East regions of India (Dr. Aanchal Kakkar, DBT)
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Evaluation of ALK, ATRX and MYC immunoexpression in Neuroblastoma and their correlation with prognostic parameters (Dr. Aanchal Kakkar, AIIMS Research Section)
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Study of Inherited Mismatch Repair deficiency and its correlation with tumor mutations burden and immune microenvironment in pediatric and adult gliomas (Dr. Kavneet Kaur, ICMR)
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Relook at adult low grade glioneuronal tumors of central nervous system beyond 2016 WHO classification (Dr. Kavneet Kaur, AIIMS Research Section)
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Comparative analysis of host immune and tissue reaction to mucormycosis between SARS-CoV-2 positive and negative patients on surgical specimens (Dr. Kavneet Kaur, AIIMS Research Section)
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Comparative analysis of the activation of EGFR/MAPK/SHH/NFKB pathways and mutation status of USP8/USP48/BRAF genes in clinically functioning and silent corticotroph pituitary adenomas to identify pharmacological targets for medical management of Cushing’s disease (Dr. Aruna Nambirajan, ICMR)
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Assessment of hypoxia inducible factor- 1 alpha pathway activation and its correlation with tumor immune microenvironment and markers of tumor invasiveness in myxopapillary ependymomas (Dr. Aruna Nambirajan, AIIMS Research Section)
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Molecular mechanisms of resistance to EGFR tyrosine kinase inhibitors in EGFR mutant non-small cell lung carcinoma (Dr. Aruna Nambirajan, AIIMS Research Section)
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Novel Molecular Subtypes of Uterine sarcoma (Dr Ruchi Rathore, AIIMS Research Section)
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The prevalence of BRCAness related somatic mutation in uterine leiomyosarcoma (Dr. Ruchi Rathore, AIIMS Research Section)
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Podocytouria in children with nephrotic syndrome: Can urine podocyte level and its growth characteristics predict steroid resistance (Dr. Lavleen Singh, DST)