Dr. Jyoti
Scientist-I
Department of Pharmacology
A.I.I.M.S, New Delhi-110029
डॉ. ज्योति
वैज्ञानिक-I
भेषजगुण विज्ञान विभाग,
अ. भ. आ. सं., नई दिल्ली-110029
Contact Details: 4th Floor, Department of Pharmacology, Teaching Block, All India Institute of Medical Sciences (AIIMS), New Delhi 110029
Telephone: 011-26593677
Email ID: This email address is being protected from spambots. You need JavaScript enabled to view it.
Education:
B.Sc. from Lucknow University, Lucknow
M.Sc (Biotechnology) from Babasaheb Bhimrao Ambedkar University, Lucknow
Ph.D in Life Sciences from Central Drug Research Institute, Lucknow
Research Interest/ area:
Endocrinology, Neurosciences
Past Position:
Research associate (THSTI), Haryana, India (June 2021 – Oct 2023)
Research associate (CDFD), Hyderabad, India (November 2019 – June 2020)
Postdoctoral research associate (University of Georgia), Georgia, USA (May 2017 – July 2019)
Postdoctoral research associate (University of Minnesota), Minnesota, USA (December 2015-April 2017)
Selected Publications:
Gautam J, Kumari D, Aggarwal H, Gupta SK, Kasarla SS, Sarkar S, Priya MRK, Kamboj P, Kumar Y, Dikshit M. Characterization of lipid signatures in the plasma and insulin-sensitive tissues of the C57BL/6J mice fed on obesogenic diets. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Jun 5;1868(9):159348.
Gautam J, Xu L, Nirwane A, Nguyen B, Yao Y. Loss of mural cell-derived laminin aggravates hemorrhagic brain injury. J Neuroinflammation. 2020 Apr 6;17(1)
Gautam J.,Cao Y. & Yao Y. Pericytic Laminin Maintains Blood-Brain Barrier Integrity in an Age-Dependent Manner. Transl. Stroke Res. (2019), Jun 18.
Gautam J, Miner JH, Yao Y. Loss of Endothelial Laminin α5 Exacerbates Hemorrhagic Brain Injury. Transl Stroke Res. 2019 Jan 29.
5. Gautam J, Nirwane A, Yao Y. Roles of Pericytes in Stroke Pathogenesis. Cell Transplant. 2018 Dec;27(12):1798-1808.
Gautam J, Khedgikar V, Kushwaha P, Choudhary D, Nagar GK, Dev K, Dixit P, Singh D, Maurya R, Trivedi R. Formononetin, an isoflavone, activates AMP-activated protein kinase/β-catenin signalling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss. Br J Nutr. 2017 Mar;117(5):645-661.
Gautam J, Nirwane A, Yao Y.Laminin differentially regulates the stemness of type I and type II pericytes. Stem Cell Res Ther. 2017 Feb 7;8(1):28
Gautam J, Zhang X, Yao Y. The role of pericytic laminin in blood brain barrier integrity maintenance. Sci Rep. 2016 Nov 3;6:36450.
Gautam J, Kumar P,Kushwaha P, Khedgikar V, Choudhary D, Singh D, Maurya R, Trivedi R. (2015) Neoflavonoid dalbergiphenol from heartwood of Dalbergia sissoo acts as bone savior in an estrogen withdrawal model for osteoporosis. Menopause.;22(11):1246-55.
Gautam J, Choudhary D, Khedgikar V, Kushwaha P, Singh RS, Singh D, Tiwari S, Trivedi R. (2014) Micro-architectural changes in cancellous bone differ in female and male C57BL/6 mice with high-fat diet-induced low bone mineral density.Br J Nutr. 111(10):1811-21
Dr. Ajay Godwin Potnuri
Scientist -I
Department of Pharmacology
A.I.I.M.S, New Delhi-110029
डॉ. अजयगॉडविनपोटनुरी
वैज्ञानिक-I
भेषजगुणविज्ञानविभाग,
अ. भ. आ. सं., नईदिल्ली-110029
Contact Details: 4th Floor, Department of Pharmacology, Teaching Block, All India Institute of Medical Sciences (AIIMS), New Delhi 110029
Telephone: 011-26593677
Email ID: This email address is being protected from spambots. You need JavaScript enabled to view it.
Education:
Research Interest/ area:
Cardiovascular Pharmacology and toxicology with a special emphasis on hypertensive heart disease and vascular biology
Past Position:
Ongoing Projects:
Completed Projects:
Selected Publications:
1. Targeting histamine-2 receptor for prevention of cardiac remodeling in chronic pressure overload AG Potnuri, L Allakonda, A Appavoo, S Saheera, RR Nair Int J Card, 2016 202, 831833.
2. Histamine 2 receptor antagonism elicits protection against doxorubicin induced cardiotoxicity in rodent model, SK Kondru, AG Potnuri, L Allakonda, P Konduri, Molecular and Cellular Biochemistry, 1-12 , 2018
3. Syk–GTP RAC-1 mediated immune-stimulatory effect of Cuscuta epithymum, Ipomoea batata and Euphorbia hirta plant extracts VS Sudam, AG Potnuri, NJP Subhashini, Biomedicine & Pharmacotherapy 96, 742-749, 2018
4. Modulation of cardiac stem cell characteristics by metoprolol in hypertensive heart disease, S Saheera, AG Potnuri, RR Nair, Hypertension Research, Nature Publishing Group 2018 Feb 15. doi: 10.1038/s41440-018-0015-7.
5. Histamine-2 receptor antagonist Famotidine Modulates Cardiac Stem Cell characteristics in hypertensive heart disease, S Saheera, AG Potnuri, RR Nair, PeerJ. 2017 Oct 9;5:e3882. doi: 10.7717/peerj.3882. eCollection 2017.
6. Crocin attenuates cyclophosphamide induced testicular toxicity by preserving glutathione redox system, AG Potnuri, L Allakonda, M Lahkar, Biomedicine & Pharmacotherapy 2018 101, 174180
7. Association of histamine with hypertension induced cardiac remodelling and reduction of hypertrophy with Histamine 2-receptor antagonist famotidine in comparison with beta blocker metoprolol, AG Potnuri, L Allakonda, A Appavoo, S Saheera, RR Nair 2018. Hypertension Research, Nature Publishing Group
8. Protective effect of antioxidant Tempol on cardiac stem cells in chronic pressure overload hypertrophy, S Saheera, AG Potnuri, RR Nair, life sciences 2019, 222, 88-93
9. Involvement of Histamine 2 receptor in Alpha 1 adrenoceptor mediated cardiac hypertrophy and oxidative stress in H9c2 cardio myoblasts, AG Potnuri, L Allakonda, S Saheera, J Cardiovasc Transl Res. 2021 Feb;14(1):184-194.
10. Beta 1 adrenoceptor blockade promotes angiogenesis in hypertrophied myocardium of TAC Rat, L Allakonda, A. Kakaraparthi, AG Potnuri. Clinical and Experimental Pharmacology and Physiology 48 (1), 121-128.
ON-GOING PROJECTS
AWARENESS/ OUTREACH
Project Title: “Assessment of awareness, perception and KAP (Knowledge, Attitude & Practices) related to common poisons and development of scientific communication modules for lifestyle modulation & year-round strategy for public awareness towards prevention of poisoning”.
Supported by- DST
PI- DR. SWATI SHARMA
National Poisons Information Centre (NPIC) in Department of Pharmacology, AIIMS, New Delhi initiated an outreach project with a theme BE CAUTIOUS, BE POISON SAFE. This theme aims to increase awareness towards poisons and poisoning among general public including Children, Parents and Occupational Workers. It also intends to increase knowledge regarding poisons and poisonous substances and disseminate knowledge of poison prevention measures that can be practiced to reduce the risk of accidental poisonings. It also advocates to adopt safe practices and enforce effective poison control measures.
Awareness activities organized in the past by National Poisons Information Centre (NPIC), AIIMS, New Delhi
Name: Dr. Devendra Singh
Designation: Scientist
Department: Pharmacology, AIIMS, New Delhi
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Educational Qualification:
M. Pharm (Pharmacology Toxicology and Therapeutics), from BVCOP, Navi Mumbai, University of Mumbai.
Ph.D. (Pharmacology) from All India Institute of Medical Sciences, New Delhi.
Awards:
Qualified GATE 2009
Qualified GPAT 2010, 2012 and 2013
Area of Interest:
Neuropharmacology, Ischemic Stroke, Alzheimer’s Disease, Preclinical research
List of Publications:
All India Institute of Medical Sciences
Ansari Nagar, New Delhi - 110029
Board Number : +91-11-26588500 / 26588700
Fax : +91-11-26588663 / 26588641