Dr. Subhradip Karmakar’s Laboratory for Placenta Biology and Molecular Oncology

Designation: Additional Professor

Address: Room No. 3020, Department of Biochemistry, Third Floor, Teaching Block, AIIMS, New Delhi

Official phone: +91-11-2659 4027

Email ID: This email address is being protected from spambots. You need JavaScript enabled to view it.

ACADEMIC PROFILES:

LinkedIn 

ResearchGate 

Google scholar

ORCID

PROFESSIONAL CAREER: 

ACADEMIC PROFILE: 

NOTABLE AWARDS:

• Best Poster Award, WCC 2018, Jaipur, India
• Best Poster presentation award, Drug Discovery and Development India 2015
• Second best poster award, Globin Switching meeting Asilomar CA 2008
  • Indian National Science Academy (INSA) young scientist award (2005) (Highest level national award for young scientist)
  • Best Postgraduate in Clinical research award in PhD, 2004
  • Best Oral presentation award, Indian Immunology Society meeting (2001)
  • Honour of Merit for University 1st Rank in Masters (MSc)
  • Endowment Award in MSc for best overall performance
  • Best Postgraduate Alumni Award (1995-1998) in Dept of Biochemistry, JIPMER, India
  • Qualified (1998,1999) {CSIR National Level Merit Exam for PhD fellowship}
  • Qualified for the state level lectureship examination for universities
  • Journal of Biomedical Sciences
  • Journal of Single Cell Biology (Omics publication group)
  • Annals of Clinical and Laboratory Research
  • BMC Bioinformatics
  • Journal of Clinical Pathology
  • Journal of Molecular Cell Biology
  • Chinese J of Cancer Research
  • Journal of Cancer Research and Therapeutics
  • Willey Science Advisor
  • Asian K Medical Science
  • Oncology Letters
  • J Med Archives
  • 1JMMD
  • PLoS One
  • World J of Surgical Oncology
  • Asian J of Reproductive Medicine
  • F1000

EDITORIAL ASSIGNMENTS:

RESEARCH PRESENTATIONS:

• ENCODE consortium, Bethesda, Maryland 2010, 2011, 2012
• American Urological Association, Annual Meeting; May 14-19, 2011, Washington
• Globin Switching meeting, Asilomar, CA 2008
• The American Society of Hematology meeting, 2006, 2007
• Congress on Reproductive Immunology, Rhodes Island, Greece 2003
• International Congress on Reproductive Immunology, Opatija, Croatia, 2001
• American Society of Hematology meeting, 2007, Atlanta

RESEARCH DOMAINS OF THE LABORATORY:

Molecular Oncology:

The laboratory employs classic molecular biology tools assisted with in silico tools to elucidate pathogenesis of various cancer including Breast Cancer, Gall Bladder Cancer, AML etc. The breast cancer project studies the cellular and molecular events pertaining to the Androgen Receptor-mediated events in Breast Cancer cell lines and validating the same in tumor obtained post-surgery. In GBC, we are exploring the role of Nuclear Receptors in the pathophysiology of gallbladder cancer and its implication in the severity of the disease. We are also investigating tumor infiltrating lymphocytes in the same. In vitro study on gallbladder cancer cell lines alteration of different phenotypic properties like migration, invasion, proliferation, apoptosis etc following treatment with different drugs targeting nuclear receptors.

Placental Biology:

Placenta is a highly specialised multifaceted organ that supports the life of growing fetus throughout the pregnancy and also serves as a source of nutrient, gaseous and waste products exchange between the mother and the fetal circulation. During the course of gestation, the placenta undergoes multiple changes which are crucial for establishing a healthy pregnancy. Placental research is aimed to identify and analyse the effect of toxic pollutants such as Sulphur dioxide and Particulate matter on the trophoblast cells and thus pregnancy. A part of my research work also warrants to identify the transgenerational effect of these pollutants on the fetal health and growth which would be achieved by performing in-silico analysis and animal experiments.

LABORATORY PERSONNEL: 

Tryambak Pratap Srivastava

 Tryambak is a final-year PhD scholar in Dr. Karmakar’s laboratory. He is working on elucidating the role of the Androgen Receptor in the pathogenesis of Breast Cancer. This prospective study is carried out simultaneously in cell lines and the subjects with breast cancer undergoing surgical interventions at AIIMS, New Delhi. His doctoral research is assisted by a group of basic scientists, pathologists, surgeons; medical, surgical, and laboratory oncologists. He remains grateful to the generous funding support from the ICMR, DHR, and SERB for laboratory funding and CSIR-UGC in terms of senior research fellowship.

Tryambak obtained his B.Sc. B.Ed. dual degrees from the Regional Institute of Education, Bhubaneswar, a constituent unit of NCERT, New Delhi. Following his graduation, he joined South Asian University (SAU), New Delhi for an M.Sc. in Biotechnology. In his masters’ dissertation, he checked the efficacy of a Pfizer drug against the HIV-1 subtype C.

Tryambak advocates open access to knowledge and information. An amateur linguist, he communicates his science, blogs, and thoughts on his website and Twitter. His profile, contact information, and other relevant details can be fetched from his website.

Sunil Kumar

 Mr. Sunil Singh has completed his Bachelor’s in 2015 from Deshbandhu College, University of Delhi, New Delhi. After B.Sc. he joined All India Institute of Medical Sciences (AIIMS), New Delhi as master’s Student and completed it in 2017. During M.Sc. he did his thesis under the mentorship of Dr. Subhradip Karmakar on the “Role of Peroxisome Proliferator Activated Receptor alpha (PPAR-α) in Human Trophoblast Invasion”. In 2018 he joined Dr. Subhradip Karmakar, Asst. Professor, Dept. of Biochemistry, AIIMS, New Delhi as PhD student and has started his work on understanding the role of toxic pollutants such as Sulphur dioxide and Particulate matter on the trophoblast cells and thus pregnancy and placentation. A part of his research work also warrants to identify the

transgenerational effect of these pollutants on the fetal health and growth which would be achieved by performing RNA-Seq and ChIP-Seq followed by depth in-silico analysis and animal experiments. 

Dr Sajib Kumar Sarkar

Dr Sajib Kumar Sarkar (MBBS, MD, DNB) is a 4th year PhD scholar with Dr Karmakar. He did his MD in Biochemistry from MAMC, New Delhi. As a part of MD thesis he worked on in vitro and animal models of insulin resistance and observed the ameliorating effect of extract of Jamun (Syzigium cumini) seed. He completed 3 years of Senior Residency from department of Biochemistry, AIIMS, New Delhi. Presently he is exploring the molecular pathogenesis of gallbladder cancer with special focus on nuclear receptors.

Neha Kashyap 

Ms. Neha Kashyap, first year Ph.D. Scholar has completed her Bachelors in Zoology Honours from “Ravenshaw University” Cuttack, Odisha. She has done her Masters in Life Sciences (Specialization in Biochemistry) from Central University of Punjab, Bhatinda. Her M.Sc. dissertation work was on the topic "miRNA mediated pathway modulation by phytochemicals: An In-silico approach" under the guidance of Dr. Shashank Kumar, Assistant Professor in the Department of Biochemistry. She got selected for the Indian Academy of Sciences “Summer Research Fellowship” project sponsored by the Indian Academy of Sciences, Bengaluru, during her graduation where she worked on the project "Analysis of Phytochemical constituents and amino acids present in green

seaweeds from South East Coast of India” under Dr.George Seghal Kiran,Assistant Professor in Pondicherry University. Later, she worked as a Junior Research Fellow (JRF) in Structural Parasitology lab, International Centre for Genetic Engineering and Biotechnology (I.C.G.E.B), New Delhi under eminent Principal Scientist Dr. Amit Sharma, Director of ICMR-NIMR in the Project "Development and validation of Hyponozite biomarkers for detecting Plasmodium vivax infection" .She also worked there on “Malarial culture and parasite proteins crystallography” .She qualified for ICMR-JRF 2020. Currently, she is working as a Ph.D. Scholar, under Dr. Subhradip Karmakar, Additional Professor in the Department of Biochemistry in All India Institute of Medical Sciences (AIIMS), New Delhi. She is working with the placenta group. Her tentative thesis is " Molecular insights into the chromatin dynamics and epigenetic changes during trophoblast fusion.”.

Lavanya Gupta

 Ms Lavanya Gupta has completed her Bachelors from Sri Venkateswara College, University of Delhi in the year 2018-2021. She has done a summer internship project on “Applications of Bioinformatics in Cardiovascular Disorders for Novel Therapeutics Design under ”SRI VENKATESWARA INTERNSHIP PROGRAM FOR RESEARCH IN

ACADEMICS(SRI-VIPRA 2020) “ which included: Identification of target receptors implicated in cardiovascular diseases , compilation of ligand libraries ,Study of ADMET properties for drug-likeness and Virtual screening by docking followed by evaluation of docking energy to find best hit. She has done ADD ON COURSE -

1)  “The Science of Stem cells “

2)   "Fundamentals of Immunology: Innate Immunity and B-Cell Function"

3)   "Understanding the Brain: The Neurobiology of Everyday Life An online course authorized by American Museum.

She was also involved in drug and development project (VISTAAR) , a science Popularisation Event organised by SVC .

Also, she was a part of mindspar ideathon event organised in Sri Venkateswara college, where she was awarded with the best presentation.

Currently, she is working as a Msc student, under Dr. Subhradip Karmakar, Additional Professor in the Department of Biochemistry in All India Institute of Medical Sciences (AIIMS), New Delhi. She is working with the placenta group. Her tentative thesis is "To study the role of estrogen regulated miRNA involved in the process of Human Trophoblast Invasion ”.

Dr. Arnab Nayek

Dr. Arnab is working as a Research Associate (Bioinformatician), in the department of Biochemistry, All India Institute of Medical Sciences, New Delhi, under the guidance of Dr. Subhradip Karmakar, Additional Professor, Department of Biochemistry. He is associated with the transcriptomics (RNA-seq) data analysis from RNA sequencing data generated from the lab as well as publicly available data from the The Cancer Genome Atlas (TCGA) database, development of integrated pipelines for NGS data analysis etc. His research credentials supported with 13 publications in referred journals and his research interest includes Next generation sequencing (NGS) data analysis from human samples to improve the disease diagnosis for clinicians, development of integrated pipelines for

NGS data analysis, protein structure modelling, protein engineering, Molecular dynamics simulations.

Dr. Joyeeta Talukdar 

Dr. Rashmi

Works on Cancer Research Related to Understand the Altruistic Mechanism and Metastasis. My focus is to understand the mechanism of cancer recurrence, and the complex biological systems that underlie its development. Further, if possible to identify new ways of treating the disease by taking a close-up look at the fundamental mechanisms at work within cells.

Dr. Rashmi Minocha has completed her Ph.D. in Biochemistry from the Ludwig Maximilian University of Munich (LMU), Germany. During the course of her Ph.D., she carried out her research work at the Gene Center, LMU Munich and at the Institute of Biochemistry, University of Gießen (Germany). The overall aim of her doctoral work was to understand how gene expression is regulated by the cross communication between its single steps using yeast as a model organism. Specifically, she worked on the biochemical and functional characterization of splicing proteins Mud2 and Prp19 complex (Prp19C).

After her Ph.D., she moved back to India and joined All India Institute

of Medical Sciences (AIIMS) in the Department of Biochemistry to pursue her interests in medical and health-based research. She is presently working as a Young Scientist Awardee (a fellowship and research grant funded by Department of Health Research). Her major research interests are:

• Establishment of three-dimensional spheroid and organoid culture systems as in vitro disease models.
• Using these pivotal model systems for understanding cancer pathogenesis, screening for potential drugs and investigating new strategies in the field of personalized medicine.
• Applying an interdisciplinary approach by using a combination of techniques from cancer biology, molecular biology, biochemistry and bioinformatics.

Her on-going focus is to apply these 3D culture systems to investigate into the molecular mechanisms which drive gallbladder carcinogenesis.

Indrani Mukherjee

 Ms. Indrani Mukherjee completed her Bachelor’s degree from Bethune College, Kolkata, the oldest women’s college in Asia with first division in Zoology. She pursued her Master’s degree in Zoology with first class from Asutosh College, University of Calcutta. Ms. Indrani completed her research training during M.Sc on the “Role of nanocapsulated flavonoidal antioxidants in combating age related cerebral ischemia-reperfusion (CIR) induced oxidative injury in rat brain” under the guidance of Dr. Nirmalendu Das, Emeritus Scientist, CSIR-Indian Institute of Chemical Biology, Kolkata. She formulated nano-encapsulated antioxidants and applied them orally to Sprague Dawley rats as a pre-treatment prior to CIR insult. She studied the rat brains for histological examinations and

expression of cellular apoptotic factors. Later, she worked under the guidance of Dr. Parasuraman Jaisankar, Senior Principal Scientist, CSIR-Indian Institute of Chemical Biology, Kolkata, in two projects. One project was entitled “A molecular docking approach to study the possible interactions between Yeast 1,4-α glucosidase and some synthetic inhibitors” where she used molecular docking to analyse the interactions between various proteins and their ligands. The second project was entitled “Isolation of enzymes from natural resources” where she used column chromatography, thin layer chromatography and HPLC for the extraction and chemical purification of phosphatases from natural resources. Ms. Indrani then worked as a Project Fellow under the guidance of Dr. Shantanu Chowdhury, Senior Principal Scientist, Functional Genomics, CSIR-Institute of Genomics and Integrative Biology, New Delhi. She focussed on learning the basic molecular biology techniques. She was involved in the amplification of pGL3 basic vector in Stbl2 strain of E.coli and its transient transfection and analysis of protein expression profile in HT 1080 cells. Currently, she is working as a PhD student under the guidance of Dr. Subhradip Karmakar, Additional Professor, Department of Biochemistry, All India Institute of Medical Sciences, New Delhi. She is a registered Ph.D scholar of Amity University, Noida, Uttar Pradesh. Her tentative thesis is entitled as “To Investigate the Role of Reactive Oxygen Species in Development of Pre-eclampsia”. Pre- eclampsia is a leading cause of maternal and neonatal mortality and morbidity and is usually diagnosed during the last trimester of pregnancy (after 20 weeks of gestation). During Pre-eclampsia, trophoblast cell migration and invasion into the maternal decidua, and vessels are typically incomplete, and thus angiogenesis and trophoblast cell proliferation are impaired. The shallow trophoblastic invasion induces placental ischemic reperfusion injury due to irregular uterine blood flow which results in the generation of reactive oxygen species (ROS). Therefore, her hypothesis is that excessive ROS generation along with an alteration of cytokine and hormonal levels in the uterine microenvironment, might contribute to the pathogenesis of Pre-eclampsia. Ms. Indrani was also awarded with CSIR-Senior Research Fellowship in the year 2019 and served as the Cultural Secretary of Society of Young Scientists (SYS), AIIMS, New Delhi, for the year 2020-2021.

Abhibroto Karmakar

 Systemic Lupus Erythematosus is a chronic, autoimmune disease with wide clinical presentation. Lupus widely affects many organs and system with no cure. The main area of our study is understanding the genomic stratification and drug responds between the patients with lupus. We keen to explore the molecular aspect of patients during lupus flare and remission. We are also looking at single nucleotide polymorphism in SLE patients focusing on Indian population. Apart from my PhD we are looking at the role of nuclear receptor in pathogenesis of gall bladder cancer.

Apart from science I love teaching dance, recitation and writing poems. I love to do solo travelling and cooking give me zeal to life. I believe education is important for all in this regard I made an YouTube channel

creating medical awareness and do career counselling in field of life sciences.

Swati Ajmeriya

Aman Saifi

Swati Ajmeriya is working as Senior Research fellow at Department of Biochemistry, AIIMS under Dr. Subhradip Karmakar. She did her masters in Biotechnology. She does research in the area of genomics using bioinformatic tools and techniques. She has worked on high-throughput exome, transcriptome and metagenomics data. She has good command over linux scripting, R and python programming. She also develops pipelines for rapid processing of genomics data. Swati's research work is primarily involved in transcriptomics and statistical genomics with applications to the identification of differentially expressed genes and genetic variants conferring susceptibility to diseases by discovering variants, genes and pathways from high-throughput data.  

Mr Aman Saifi is working as a Junior Research Fellow on a project called "Molecular Analysis to explore resistance against receptor tyrosine kinase inhibitors (RTKI) in Renal Cell Carcinoma (RCC) and the prognostic role of circulating tumour cells in patients with metastatic RCC (mRCC). He has completed his Bachelor's and Master's Integrated Degree in Biotechnology from Amity University, Uttar Pradesh. He qualified GATE exam in 2021 as well as in 2022. His university awarded him a merit scholarship during his coursework. He was selected for the summer internship program at Jawaharlal Nehru University. He worked on the project "standardizing the IR64 rice seeds tissue culture protocol for the plant transformation with Agrobacterium tumefaciens harbouring  pCAMBIA1304 vector". Later, for his master's thesis, he worked on the project "standardization of differentiation of bone cell precursors (macrophages and mesenchymal stem cells) into mature bone cells (osteoclast and osteoblast cells)" in the department of Biotechnology, AIIMS

ALUMNI: 

PUBLICATIONS:

·         Dhar, Ruby; Talukdar, Joyeeta; Nayek, Arnab; Ajmeriya, Swati; Kumar, Arun; Karmakar, Subhradip; 2022Unveiling the omicron B. 1.1. 529: the variant of concern that is rattling the globe Asian Journal of MedicalSciences13(1),pp.166-168

·         Pethusamy, Karthikeyan; Dhar, Ruby; Kumar, Arun; Karmakar, Subhradip; 2022 Cell to cell hijacking: RoleofmembranenanotubesAsianJournalof MedicalSciences13(1),pp.44593

·         Dhar, Ruby; Kumar, Arun; Karmakar, Subhradip; 2022 How COVID pandemic may end: Co-existence isthekeyAsianJournal ofMedicalSciences13(2),pp.44593

·         Ajmeriya, Swati; Kumar, Amit; Karmakar, Subhradip; Rana, Shweta; Singh, Harpreet;2022 Neutralizing Antibodies and Antibody-Dependent Enhancement in COVID-19: A Perspective Journal of the IndianInstituteofScience(),pp.42736 ·         Dhar, Ruby; Talukdar, Joyeeta; Kumar, Arun; Karmakar, Subhradip; 2022 The problem with APC and openaccess:HurdlesinpublishingpracticeAsianJournalofMedicalSciences13(3),pp.44593

·         Dhar, Ruby; Kumar, Arun; Karmakar, Subhradip; 2022 The innocence of Omicron: Taking the right decisionAsian JournalofMedicalSciences 13(3),pp.170-171

·         Guha, Samudra; Talukdar, Joyeeta; Karmakar, Abhibrato; Goswami, Sandeep; Kumar, Arun; Dhar, Ruby;Karmakar, Subhradip;2022 Synthetic biology: The new era Asian Journal of Medical Sciences 13(4),pp.200-203 ·         Bharat, SS; Makkar, N; Karmakar, S; Singh, AK; 2022 A novel technique to widen the 1st web space byusing'spareparts'ofthumbpolydactylySriLanka JournalofSurgery40(1),pp.

·         Talukdar, Joyeeta; Srivastava, Tryambak Pratap; Gogoi, Gayatri; Rai, Avdhesh; Dhar, Ruby; Karmakar,Subhradip;2022Oncometaboliteprofilingidentifyingestrogen-responsivegenesinbreastcancer.(),pp.

·         Singh, Sunil; Dhar, Ruby; Karmakar, Subhradip;2022 Fenofibrate mediated activation of PPARα negativelyregulatestrophoblastinvasionPlacenta 126(),pp.140-149

·         Srivastava, Tryambak Pratap; Dhar, Ruby; Srivastava, Anurag; Deo, SVS; Parshad, Rajinder; Karmakar,Subhradip;2022 Functional characterization of Androgen Receptor splice variants in breast cancerinvasionandmetastasisCancerResearch82(12_Supplement), pp.6398-6398

·         Dhar, Ruby; Rana, Shweta; Srivastava, Tryambak Pratap; Nayek, Arnab; Sharma, Jai Bhagwan; Kaur,Digjeet;Kalari,KrishnaR;Singh,Harpreet;Karmakar,Subhradip;2022India’sOpportunitiesand Challenges in Establishing a Twin Registry: An Unexplored Human Resource for the World’s Second-MostPopulousNationTwinResearchandHumanGenetics(),pp.44805

·         Talukdar, D; Haldar, AK; Dastidar, R; Kumar, S; Lodha, M; Banerjee, A; Karmakar, S; Sikder, K;2022Inflammation-related Biomarkers Are Associated With Severity Of Idiopathic Dilated Cardiomyopathy (IDCM): ABrief Report On Patients Of West Bengal, India Journal of Cardiovascular Disease Research (),pp.1693-1701

·         Sahoo, Om Saswat; Pethusamy, Karthikeyan; Pratap Srivastava, Tryambak; Talukdar, Dr; Alqahtan,Mohammed S; Abbas, Mohamed; Dhar, Ruby; Karmakar, Subhradip;2022 The metabolic addiction ofcancerstemcells FrontiersinOncology (),pp.3655 ·         Mukherjee, Indrani; Singh, Sunil; Biswas, Subhrajit; Talukdar, Joyeeta; Alqahtani, Mohammed S; Abbas,Mohamed; Nag, Tapas Chandra; Mridha, Asit; Gupta, Surabhi; Sharma, Jai Bhagwan;2022 Monosodiumglutamate (MSG) perturbs trophoblast differentiation and invasion program through a ROS mediatedpathway(),pp.

·         Jalandra, Rekha; Dhar, Ruby; Pethusamy, Karthikeyan; Sharma, Minakshi; Karmakar, Subhradip;2022Dysbiosis:Gut feeling F1000Research11(),pp.911

·         Talukdar, Joyeeta; Srivastava, Tryambak; Karmakar, Abhibrato; Purkaystha, Kakali; Goswami, Sandeep;Kumar, Arun; Dhar, Ruby; Karmakar, Subhradip; 2022 Malaria vaccine: The tale of terror, triumph, tyranny,andtrustAsianJournalofMedical Sciences 13(9),pp.252-257 ·         Pethusamy, Karthikeyan; Seethy, Ashikh; Dhar, Ruby; Karmakar, Abhibroto; Chaudhary, Shilpi; Bakhshi,Sameer; Chopra, Anita; Chauhan, Shyam S; Karmakar, Subhradip;2022 Loss of TET2 with reducedgenomic 5-hmC isassociatedwithadverse-riskAMLLeukemia &Lymphoma(),pp.44743·         Seethy, Ashikh A; Singh, Sunil; Mukherjee, Indrani; Pethusamy, Karthikeyan; Purkayastha, Kakali; Sharma, Jai Bhagwan; Sharma, Radhey S; Dhar, Ruby; Karmakar, Subhradip;2021 Potential SARS-CoV-2 interactionswithproteinsinvolvedintrophoblastfunctions–anin-silicostudyPlacenta103(),pp.141-151

·         Nayak, Brusabhanu; Panaiyadiyan, Sridhar; Singh, Prabhjot; Karmakar,Subhradip;Kaushal,Seema;Seth,Amlesh;2021 Role of circulating tumor cells in patients with metastatic clear-cell renal cell carcinoma UrologicOncology: SeminarsandOriginalInvestigations39(2),pp.135. e9-135.e15

·         Pethusamy,Karthikeyan;Seethy,AshikhA;Kulandhasamy,Maheshwari;Garg,Pinki;Chowdhury,Debashish;Agarwal,Sarita;Kumar,Arun;Dhar,Ruby;Karmakar,Subhradip;2021Effectsof469E/K

polymorphismofICAM1geneinischemicstrokeanditsassociationwithstrokeseverityandoutcomeAsianJournalofMedical Sciences 12(1), pp.44744

·         Chattopadhyay, Indranil; Dhar, Ruby; Pethusamy, Karthikeyan; Seethy, Ashikh; Srivastava, Tryambak; Sah, Ramkishor;Sharma,Jyoti;Karmakar,Subhradip;2021ExploringtheroleofgutmicrobiomeincoloncancerAppliedbiochemistry and biotechnology 193(6),pp.1780-1799

·         Dhar, Ruby; Jee, Babban; Karmakar, Subhradip; 2021 Balancing Healthcare and Economy Amidst theCOVID-19Pandemic:AnIndianExperienceRiskManagementandHealthcare Policy14(),pp.827

·         Seethy, Ashikh; Pethusamy, Karthikeyan; Chattopadhyay, Indranil; Sah, Ramkishor; Chopra, Anita; Dhar,Ruby; Karmakar, Subhradip;2021 TETology: epigenetic mastermind in action Applied Biochemistry andBiotechnology193(6),pp.1701-1726

·         Jee, Babban; Dhar, Ruby; Singh, Sunil; Karmakar, Subhradip;2021 Heat shock proteins and their role inpregnancy: Redefining the function of “Old Rum in a New Bottle” Frontiers in Cell and DevelopmentalBiology9(),pp.648463 ·         Panaiyadiyan, Sridhar; Nayak, Brusabhanu; Singh, Prabhjot;Kaushal,Seema;Karmakar,Subhradip;Seth,Amlesh;2021 Prognostic and predictive role of intra-tumoral CXCR1 expression in patients receivingtyrosine kinase inhibitors for metastatic clear-cell renal cell carcinoma Journal of Clinical Urology (),pp.20514158211012200

·         Talukdar, Joyeeta; Karmakar, Abhibroto; Dhar, Ruby; Kumar, Arun; Karmakar, Subhradip;2021 Non GovernmentOrganizations(NGO)-ThegapfillersduringCOVID-19lockdowninAssam,IndiaAsianJournalofMedical Sciences12(6), pp.115-121

·         Dhar, Ruby; Pethusamy, Karthikeyan; Talukdar, Joyeeta; Karmakar, Abhibrato; Kumar, Arun; Karmakar,Subhradip;2021 The curious case of COVID-19: Its murky origin, negligence and a botched internationalattemptforacover-upAsianJournalof Medical Sciences12(7),pp.146-148

·         Dhar, Ruby; Seethy, Ashikh; Singh, Sunil; Pethusamy, Karthikeyan; Srivastava, Tryambak; Talukdar,Joyeeta; Rath, Goura Kishor; Karmakar, Subhradip; 2021 Cancer immunotherapy: Recent advances andchallengesJournalofCancerResearchandTherapeutics17(4),pp.834 ·         Dhar, Ruby; Kumar, Arun; Karmakar, Subhradip; 2021 Menopause and COVID19 severity: The missinglinkAsianJournalofMedical Sciences 12(9),pp.44621

·         Mukherjee, Indrani; Dhar, Ruby; Singh, Sunil; Sharma, Jai Bhagwan; Nag, Tapas Chandra; Mridha, AsitRanjan;Jaiswal,Parul;Biswas,Subhrajit;Karmakar,Subhradip;2021Oxidativestress-inducedimpairment of trophoblast function causes preeclampsia through the unfolded protein response pathwayScientificreports11(1),pp.43831

·         Dhar, Ruby; Pethusamy, Karthikeyan; Jee, Babban; Karmakar, Subhradip;2021 Fault Lines in India’s COVID-19Management:LessonsLearnedandFutureRecommendationsRiskManagementandHealthcare Policy 14(),pp.4379 ·         Dhar, Ruby; Kumar, Arun; Karmakar, Subhradip; 2021 Spatial transcriptomics: Gene expression in space,time andnumbersAsianJournal of Medical Sciences12(11),pp.44593

·         Saluja, Sumedha; Singh, Jay; Jain, Ayushi; Chaudhary, Shilpi; Pethusamy, Karthikeyan; Chattopadhyay,Parthaprasad; Bakhshi, Sameer; Chopra, Anita; Singh, Archna; Karmakar, Subhradip;2021 Delineatingthe Role of Interplay between m6A Machinery Genes and IGF2BP Group of RNA-Binding Proteins in B-CellAcuteLymphoblasticLeukemia(B-ALL)Blood138(),pp.4472

·         Dhar, Ruby; Kumar, Arun; Karmakar, Subhradip; 2021 The science of “smell” and the noble for “hugs:”making“sense?”AsianJournalofMedicalSciences 12(12),pp.44593

·         Bagri, Narendra Kumar; Karmakar, Subhradip; Haldar, Partha; Lodha, Rakesh; Kabra, SK;2021 Role ofserum MRP8/14 in predicting response to methotrexate in children with juvenile idiopathic arthritis JCR: JournalofClinicalRheumatology27(8),pp.e336-e341 ·         Deka, Kamalika Bhandari; Sarma, Pallavi; Sarma, Anupam; Das, Gaurav; Karmakar, Subhradip; Rath,Goura Kishore; Rai, Avdhesh Kumar;2021 Prevalence of Epstein–Barr virus in North-East Indian breastcancerpatients'bloodAnnalsofOncologyResearchandTherapy 1(2),pp.111

·         Sil, Suparba; Dhar, Ruby; Karmakar, Subhradip; 2021 The Perils ofthePandemicandIndia'sChildVictimsofCovid-19InternationalJournalofChildHealthand Nutrition10(4),pp.148-153

·         Seethy, Ashikh A; Singh, Sunil; Mukherjee, Indrani; Pethusamy, Karthikeyan; Purkayastha, Kakali; Sharma, Jai Bhagwan; Dhar, Ruby; Karmakar, Subhradip;2020 An In Silico Analysis of Potential SARS-CoV-2Interactionswith Proteins InvolvedinPlacentalFunctions(),pp.

 ·         Dhar, Ruby; Sinha, Akhauri Yash; Seethy, Ashikh; Matta, Sri Anusha; Pethusamy, Karthikeyan; Srivastava, Trymbak; Singh,Sunil;Mukherjee,Indrani;Sarkar,Sajib;Minocha,Rashmi;2020GenotypicandantigenicstudyofSARS-CoV-2from anIndianisolatebioRxiv(),pp.

·         Karmakar, Subhradip; Dhar, Ruby; Jee, Babban;2020 Covid-19: research methods must be flexible in acrisisbmj 370(),pp.

·         Karmakar, Subhradip; Dhar, R; Purkayastha, K; Seth, R; Karmakar, S; 2020 To investigate the role of BRAF V600Eco-occurringmutationsinLangerhanscellhistiocytosis(LCH)CancerResearch80(16_Supplement), pp.3127-3127

·         Dhar,Ruby;Singh,Sunil;Mukherjee,Indrani;Pethusamy,Karthikeyan;Purkayastha,Kakali;Das,Prasenjit; Sharma, Jai Bhagwan; Sharma, Radhey Shyam; Karmakar, Subhradip;2020 MTiness inpseudo-malignant behavior of trophoblasts during embryo implantation Frontiers in Bioscience-Landmark26(4),pp.717-743

·         Dhar, Ruby; Jee, Babban; Pethusamy, Karthikeyan; Seethy, Ashikh; Kumar, Arun; Karmakar, Subhradip;2020ThescarsofCOVID19:PreparingforthecollateraldamagesAsianJournalofMedicalSciences11(6),pp.142-147

·         Sathe, Gajanan;George,Irene A;Deb,Barnali;Jain, AnkitP;Patel,Krishna;Nayak,Brusabhanu;Karmakar, Subhradip; Seth, Amlesh; Pandey, Akhilesh; Kumar, Prashant;2020 Urinary glycoproteomic profiling of non-muscle invasive and muscle invasive bladder carcinoma patients reveals distinct N- glycosylationpatternof CD44,MGAM, andGINM1Oncotarget11(34), pp.3244

·         Dhar,Ruby;Jee,Babban; Talwar,GursaranPran;Karmakar,Subhradip;2020Repurposinganti-tuberculosis and anti-leprosy vaccine against COVID-19 disease: an Indian experience Current Science119(7),pp.1078         Dhar, Ruby; Mukherjee, Indrani; Singh, Sunil; Goswami, Sandeep; Karmakar, S;2019 Role of Carbon MonoxideSignalingDuringtrophoblastInvasioninHumansOpenAccessJournalofReprouctiveSystemsand SexualDisorders 2(2),pp.186-191·         Dhar, Ruby; Seethy, Ashikh; Pethusamy, Karthikeyan; Singh, Sunil; Rohil, Vishwajeet; Purkayastha, Kakali; Mukherjee, Indrani;Goswami,Sandeep;Singh,Rakesh;Raj,Ankita;2019DenovoassemblyoftheIndianblue peacock (Pavo cristatus) genome using Oxford Nanopore technology and Illumina sequencingGigaScience8(5),pp.giz038

·         Dhar, Ruby; Rath, Goura Kishor; Karmakar, Subhradip;2019 FBXO4 as a novel ubiquitin ligase that targetsCyclinDin thepathogenesisofbreastcancer.(),pp.

·         Dhar, Ruby; Pethusamy, Karthikeyan; Singh, Sunil; Mukherjee, Indrani; Seethy, Ashikh; Sengupta, Bharoti;Srivastava, Tryambak; Sarkar, Sajib; Mandal, Vikramjit; Karmakar, Madhumita;2019 Draft genome ofOmpokbimaculatus(Pabdafish)BMC ResearchNotes12(1),pp.44621

·         Zhou,Ying;Unno,Kenji;Hyjek,Elizabeth;Liu,Hui;Zimmerman,Todd;Karmakar,Subhradip;Putt,KarsonS;Shen,Jiayin;Low,PhilipS;Wickrema,Amittha;2018Expressionoffunctionalfolatereceptorsinmultiplemyeloma Leukemia& lymphoma 59(12), pp.2982-2989

·         Kathuria, S; Karmakar, S; Singh, A; Singh, SP;2017 Squamous cell carcinoma arising from hypertrophiclichenplanus IndianDermatology Online Journal8(4),pp.288

·         Dhar, R; Karmakar, S;2016 Role of a novel ubiquitin ligase FBXO4 in pathogenesis of breast cancerEUROPEANJOURNALOFCANCER54(),pp.S14-S14

·         Karmakar,S;2016ReducedDOCK4expressionleadstoerythroiddysplasiain-7/del(7q)myelodysplasticsyndromesEUROPEANJOURNALOF CANCER 54(),pp.S46-S47

·         Sundaravel, Sriram; Duggan, Ryan; Bhagat, Tushar; Ebenezer, David L; Liu, Hui; Yu, Yiting; Bartenstein,Matthias; Unnikrishnan, Madhu; Karmakar, Subhradip; Liu, Ting-Chun; 2015 Reduced DOCK4 expressionleads to erythroid dysplasia in myelodysplastic syndromes Proceedings of the National Academy ofSciences112(46),pp.E6359-E6368

·         Li, Guoqiang; Ci, Weimin; Karmakar, Subhradip; Chen, Ke; Dhar, Ruby; Fan, Zhixiang; Guo, Zhongqiang;Zhang,Jing;Ke,Yuwen;Wang,Lu;2014SPOPpromotestumorigenesisbyactingasakeyregulatoryhubinkidney cancerCancercell 25(4),pp.455-468

·         Karmakar, S;2014 Cell Based Immunotherapy: As a Promising Futuristic Solution for Effective CancerTherapyOmics International 3(1),pp.105

·         McNerney, Megan E; Brown, Christopher D; Wang, Xiaoyue; Bartom, Elizabeth T; Karmakar, Subhradip;Bandlamudi, Chaitanya; Yu, Shan; Ko, Jinkyung; Sandall, Barry P; Stricker, Thomas;2013 CUX1 is ahaploinsufficienttumorsuppressorgeneonchromosome7frequentlyinactivatedinacutemyeloidleukemiaBlood,TheJournal oftheAmericanSocietyofHematology 121(6),pp.975-983

·         Liu, Li; Karmakar, Subhradip; Dhar, Ruby; Mahajan, Milind; Choudhury, Alina; Weissman, Sherman; Pace,Betty S;2013 Regulation of Gγ-globin gene by ATF2 and its associated proteins through the cAMP- responseelementPloSone8(11),pp.e78253

·         Prasad, Sandip;Karmakar,Subhradip;Cai,Yi;VanderGriend,Donald;White,Kevin;Eggener,Scott;2012

145 SPECKLE-TYPE POZ PROTEIN CYTOPLASMIC MISLOCALIZATION AND OVEREXPRESSIONPROMOTE TUMOR GROWTH IN AN ORTHOTOPIC MURINE RENAL CELL CANCER MODEL TheJournalofUrology 187(4S),pp.e60-e60