Prof. Sujata Sharma
- Last Updated On :
Prof. Sujata Sharma
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| Designation | Professor | |||||
| sujatasharma.aiims@gmail.com | ||||||
| Contact Number | +91-11-26594608 ; +91-11-26593201 | |||||
| Research Interests | Protein Structure Determination ; Rational Structure based Drug Design ; Multidrug Resistant Bacterial Therapeutics | |||||
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| Recent Significant Publications
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Sharma, S., Kaushik, S., Sinha, M., Singh, A., Sikarwar, J., Chaudhary, A., Gupta, A., Kaur, P. & Singh, T.P. (2014). Structural and functional insights into Peptidyl-tRNA Hydrolase. Biochem. Biophys. Acta.1844 : 1279-1288 | |||||
| Rastogi, N., Singh, A., Pandey, S.N., Sinha, M., Bhushan, A., Kaur, P., Sharma, S. & Singh, T.P. (2014). Structure of the iron-free true C-terminal half of bovine lactoferrin produced by tryptic digestion and its functional significance in the gut. FEBS J. 281 : 2871-2882. | ||||||
| Rastogi, R., Nagpal, N., Alam, N., Pandey, S., Gautam, L., Sinha, M., Shin, K., Manzoor, N., Virdi, J.S., Kaur, P., Sharma, S. & Singh, T.P. (2014) Preparation and Antimicrobial Action of Three Tryptic Digested Functional Molecules of Bovine Lactoferrin. Plos One (2014) 9 : e90011. | ||||||
| Sharma, S., Sinha, M., Kaushik, S., Kaur, P. & Singh, T.P. (2014). C-lobe of lactoferrin : The whole story of a half molecule. Biochem. Res. Int. (2013) Vol. 2013 : e271641. | ||||||
| Sharma, S., Singh, A.K., Kaushik, S., Sinha, M., Singh, R.P., Sharma, P., Sirohi, H., Kaur, P. & Singh, T.P. (2013) Lactoperoxidase : Stuctural Insights into Function, Ligand Binding and Inhibition. Int. J. Biochem. Mol. Biol. 4, 108-128. | ||||||
| Kaushik, S., Singh, N., Yamini, S., Singh, A., Sinha, M., Arora, A., Kaur, P., Sharma, S. & Singh, T.P. (2013). The Mode of Inhibitor Binding to Peptidyl-tRNA Hydrolase: Binding Studies and Structure Determination of Unbound and Bound Peptidyl-tRNA Hydrolase from Acinetobacter baumannii. PLoS One. 8 : e67547. | ||||||
| Mir, R., Singh, N., Vikram, G., Kumar, R.P., Sinha, M., Bhushan, A., Kaur, P., Srinivasan, A., Sharma, S. & Singh, T.P. (2009)). Structural basis of the prevention NSAID-induced d amage of the gastrointestinal tract by C-terminal half (C-lobe) of bovine colostrums protein lactoferrin: Binding andstructural studies of the C-lobe complexes with indomethacin, diclofenac, aspirin and ibuprofen. Biophys. J. 97, 3178-3186 | ||||||
| Mir, R., Singh, N., Vikram, G., Sinha, M., Bhushan, A., Kaur, P., Srinivasan, A., Sharma, S. & Singh, T.P. (2010). Structural and binding studies of C-terminal half (C-lobe) of lactoferrin protein with COX-2-specific non-steroidal anti-inflammatory Drugs (NSAIDs). Arch. Biochem. Biophy. 500, 196-202 | ||||||
| Sharma, S., Jasti, J., Kumar. J., Mohanty, A.K. & Singh, T.P. (2003). Crystal structure of a proteolytically generated functional monoferric C-lobe of bovine lactoferrin at 1.9Å resolution. J. Mol. Biol. 321, 1286-1296. | ||||||
