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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi
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PROF. M. IRSHAD

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Phone : 91-11-26594981 (O)

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PROF. M. IRSHAD
( Ph.D , MNAMS , MNYASc. (USA) , FIMSA )

HEAD

DEPARTMENT OF LABORATORY MEDICINE, AIIMS

Experience at AIIMS

Joined AIIMS in 1981 ;Recruited as a faculty member in 1991.

Researchspecialities

Clinical & Basic Biochemistry, Clinical Immunology, Molecular Biology with major contribution in liver diseases (Viral Hepatitis).

Professional Experience

Teaching (U.G./P.G. ), academic and research experience in medical science ( > 35 years ).

Awards / Fellows

(1)Dr. DharamvirDatta Memorial Oration Award( ICMR ) : 1990

(2) “RashtriyaGaurav Award” :2010

(3) “Best Citizen of India” :2010

(4) “Bharat Jyoti Award” :2013

(5) “Indira Gandhi Shiromani Award” :2014

(6) “Mahatma Gandhi EktaSamman” : 2015

(7) “Bharat Ratna Dr. APJ Abdul Kalam Excellence Award” : 2017

 

Medals / Prizes

(1) National Merit Scholarship for a distinct position in H.Sc. U.P. Board Examn. (1969-73)

(2) Gold-Medal for top rank in University (1975)

(3) Best-prize for running a chemical society in college, as president of thesociety (1975)

Thesis Guide / Co-guide

Ph.D. : 18

D.M./M.Ch. : 10

M.D. : 26

M.Sc. : 3

Publications

Res. Publications : 153

Chapters in Books : 4

Abstracts : 28

Project Investigator

Principal Investigator : 15

Co-Investigator : 10

Memberships of Academic & Scientific Societies

(1) New York Academy of Science : 1995

(2) National Academy of Medical Sciences (NAMS) : 1998

(3) Fellow of International Medical Sciences Academy ( FIMSA ): 1999

(4) Digestive Disease Foundation :1988

(5) American Association of Clinical Chemist : 2004

Member of Committees

1.WHO Surveillance Committee on Viral Hepatitis :1984-1988

2. Staff Selection Committee :1992-onwards

3. Project Review Committee :1995-onwards

4. Departmental Promotional Committee :2000-onwards

5. Board of Counseling of PG Examination :1994-2008

6. Member, Staff Selection Board (UPSC) :2002- onwards

7. Animal Ethics Committee,AIIMS :2007-2008

8. National Tobacco Control Program :2008-2009

9. Member, Store Purchase Committee, AIIMS :2013-onwards

 

Member of Review / Editorial Board

Several Indian & foreign journals including IJMR, IMJ, GUT, BMJ, JVM, VRT , BMC Mol.

Biol., Med. Sci. Monitor, IJBB, JIMSA, Virology, BMC Gastroenterology, JGH, IRI, WJG

Hepatitis Monthly, Cancer Letters, Gastro. Research, IJMMS, Viral Immunol., MJMS, HI,

Elsevier & Blackwell publications.

1. Nominated as the Member of Editorial Board for World Journal of Hepatology (WJH) since March, 2013.

2. A compliment of “EXCELLENT PAPER” submitted to Journal of Gastroenterology &Hepatology by its Editor in 2013.

3. Grading of review article published in “International Reviews of Immunology” to be one among 1% best paper of the world.

Responsibilities

(1) U.G. / P.G. teaching

(2) Academic& Research

(3) Management of patients’ investigations (a major responsibility)

(4) Several administrative and academic duties assigned periodically by AIIMS administration.

 

Contribution

Notable contributions in: Improvement & modernization of patients investigative area; commencement of U.G. / P.G. teaching and research in the department of Laboratory Medicine, AIIMS.

 

Personal biography included in

1. All post 1995 Editions of "Who's Who in the World", by Marqui's Who's Who, USA

2. All post 1998 Editions of “International Directory” of distinguished leadership (ABI, USA) {2007& 2008}

3. Outstanding scholars (IBC, Cambridge)

4. The Asia 500 leaders (Baron’s Who’s Who USA)

 

Conferences

Regularly invited to deliver guest lecture and chair the session in several national and international conferences.

LIST OF PUBLICATIONS

( Prof. M. IRSHAD, AIIMS )

HEPATITIS - A, B, NANB

  1. Irshad M. Nucleic acid hepatitis B virus (HBV) vaccine : current status.Hepatol. Res. (1998) ; 13 : 71 - 79.
  2. Irshad M,Acharya SK. Status of Hepatitis viral markers in patients with acute and chronic liver diseases in northern India. Intervirology. (1994) ; 37 : 369 - 372.
  3. Irshad M, Gandhi BM, Acharya SK, Joshi YK, Tandon BN. Significance of anti-Pre-S antibodies in patients with fulminant hepatic failure. Gastro. Japonica. (1990) ; 25 : 258 - 261.
  4. Irshad M, Gandhi BM, Acharya SK, Joshi YK, Tandon BN. Anti -Pre-S antibodies in different groups of patientswith hepatitis B virus (HBV) infection. J. Gastroenterol. &Hepatol. (1989) ; 4 : 25 - 32.
  5. Irshad M, Gandhi BM, Acharya SK, Joshi YK, Tandon BN. Anti -Pre-S antibodies in patients with fulminant hepatic failure. Hep. Sci. Memo. (1989) ; Memo-H- 2417.
  6. Irshad M, Gandhi BM, Acharya SK, Joshi YK, Tandon BN. An enzyme-linked immunosorbent assay (ELISA) for the detection of IgG and IgM anti-idiotypes directed against anti-HBs molecules. J. Immunol. Meth. (1987) 96 : 211 - 217.
  7. Irshad M, Gandhi BM, Acharya SK, Tandon BN. Relation between HBsAg binding with polymerized human serum albumin and HBV replication. Intervirology. (1987) ; 27 : 91 - 94.
  8. Irshad M, Gandhi BM, Chawla TC, Acharya SK, Joshi YK, Tandon BN. Studies on HBsAg binding with polymerised human serum albumin by ELISA. J. Virol. Meth. (1987) ; 16 : 75 - 85.
  9. Irshad M, Gandhi BM, Tandon BN. Further characterization of HBsAg binding with polymerized human serum albumin by ELISA technique. Hep. Sci. Mem. (1986) ; Memo-H 2263 : 24.
  10. Tandon BN, Gandhi BM, Joshi YK, Irshad M, Gupta H. Hepatitis virus non-A, non-B: the cause of a major public health problem of India. Bulletin of the World Health Organization. (1985) ; 63 : 931 - 934.
  11. Tandon BN, Joshi YK, Gandhi BM, Irshad M, Gupta H, Gupta ML. Epidemiology of HBsAg carriers in India. A holistic approach to control of hepatitis-B-reservoir. J. Gastroenterol&Hepatol. (1986) ; 1: 39 – 43.
  12. Tandon BN, Gupta H, Irshad M, Joshi YK, Chawla TC. Associated infection with non-A, non-B virus as possible cause of liver failure in Indian HBV-carriers. The Lancet. (1984) ;2 : 750 - 751.
  13. Irshad M, Peter S. Spectrum of viral hepatitis in thallassemic children receiving multiple blood transfusions. Ind. J. Gastroenterol. (2002) ; 21 : 183 - 184.
  14. Irshad M, Joshi YK, Gupta H, Acharya SK, Singh YN, Tandon BN. HBV transmission in healthy persons at high risk in India. The Nat. Med. J. India. (1992) ; 4 : 40.
  15. Irshad M,Acharya SK. An update on viral hepatitis. Trop. Gastroenterol. (1992) ; 13 : 11 - 20.
  16. Irshad M, Singh YN, Acharya SK. HBV-status in professional blood donors in north India. Trop. Gastroenterol. (1992) ; 13 : 112 - 114.
  17. Irshad M, Singh YN. Prevalence of HBV markers in hemophiliacs and Eunuchs in India. Ind. J. Gastroenterol. (1991) ; 10 : 154 - 155.
  18. Irshad M, Joshi YK, Acharya SK, Tandon BN. Prevalence of hepatitis B virus infection in healthy persons in north India. The Nat. Med. J. India. (1994) ; 7 : 210 - 212.
  19. Dasarathy S, Misra SC, Acharya SK, Irshad M, Joshi YK, Venugopal P, Tandon BN. Prospective controlled study of post transfusion hepatitis after cardiac surgery in a large referal hospital in India. Liver. (1992 ) ; 12 : 116 - 120.
  20. Agarwal SK,Irshad M, Dash SC. Comparison of two schedules of hepatitis B vaccination in patients with mild, moderate and severe renal failure. J. Assoc. Phys. India(JAPI). (1999) ; 47 : 183 - 185.
  21. Arora NK, Ganguly S, Agadi SN, Irshad M, Kohli R, Deo M, Paul VK, Deorari AK. Hepatitis B immunization in low birth weight infants : do they need an additional dose? Acta. Paediatr. (2002) ; 91 : 995 - 1001.
  22. Tandon BN, Gandhi BM, Joshi YK, Gupta H, Irshad M. Subclinical hepatitis A in north Indian children. The Lancet. (1984); 323 : 335 - 336.
  23. Moudgil KD, Irshad M. Global overview of the prevalence of hepatitis B virus markers (HBsAg and anti-HBs) in leprosy patients. Trop. Gastroenterol. (1988); 9: 184 - 190.
  24. Kumar A, Acharya SK, Joshi YK, Gandhi BM, Irshad M,Tandon BN. Role of immune serum globulin in post-transfusion virus B infection. Ind. J. Med. Res. (1989) ; 89 : 12 - 15.
  25. Gandhi BM, Irshad M,Tandon BN. A low budget Disc-ELISA for Hepatitis-B surface Antigen (HBsAg).Trop.Gastroenterol. (1989); 10 : 111 - 116.
  26. Gandhi BM, Irshad M,Tandon BN. A low cost micro-ELISA test for detection of antibodies to hepatitis - B - surface antigen. Trop. Gastroenterol. (1985) ; 6 : 148 - 154.
  27. Gandhi BM, Gupta H, Irshad M, Joshi YK, Tandon BN. Significance of circulating HBsAg/IgM complexes in viral hepatitis type B. Ind. J. Med. Res. (1986) ; 84 : 27 - 31.
  28. Patwari SI, Irshad M, Gandhi BM, Joshi YK, Nundy S, Tandon BN. Increasing HBV reservoir by post transfusion HBV infection in India. Ind. J. Med. Res. (1986) ; 84 : 227 - 229.
  29. Patwari SI, Irshad M, Gandhi BM, Joshi YK, Nundy S, Tandon BN. Post-transfusion hepatitis-A prospective study. Ind. J. Med. Res. (1986) ; 84 : 508 - 510.
  30. Gandhi BM, Irshad M,Acharya SK, Joshi YK, Tandon BN. Hepatitis B virus replication in patients with chronic liver diseases. Gastro. Japonica. (1990) ; 25 : 258 - 264.
  31. Singh YN, Irshad M, Gandhi BM, Khare SK, Malaviya AN. Delhi prostitutes pose no additional threat of HBV transmission. The J. Assoc. Phys. India. (1991) ; 39 : 228.
  32. Tandon BN. Irshad M,ManikyaRaju, Mathur GP, Rao MN. Prevalence of HBsAg and Anti-HBs in children and strategy suggested for immunisation in India. Ind. J. Med. Res. (1991) ; 93 : 337 - 339.
  33. Moudgil KD, Irshad M, Gandhi BM, Mishra R. Serological pattern of hepatitis B virus markers (HBsAg, Anti-HBs, IgM Anti-HBc and HBV specific DNA polymerase) in leprosy patients. Ind. J. Lepr. (1989) ; 61 : 54 - 60.
  34. Tandon BN, Gandhi BM, Irshad M,Acharya SK, Joshi YK. Prevalence of amoebic antibody in population affected by epidemic Non-A, Non-B hepatitis. The Lancet. (1987) ; 329 : 455 - 456.
  35. Tandon BN, Gandhi BM, Joshi YK, Irshad M, Gupta H. NANB waterborne hepatitis in India.Gastroenterology. (1985) ; 88 : 1698.
  36. Gandhi BM, Irshad M,Acharya SK, Joshi YK, Tandon BN. Virus B multiplication in fulminant hepatitis. HepSci Memo. (1987) ; Memo-H- 2312.
  37. Acharya SK, Irshad M, Gandhi BM, Joshi YK. Pre-S proteins-A new marker for the hepatitis B virus. Trop. Gastroenterol. (1987) ; 8 : 91 - 98.
  38. Gandhi BM, Irshad M,Acharya SK, Joshi YK, Tandon BN. Evidence of ongoing virus multiplication in type B fulminant hepatitis. J. Gastroenterol. &Hepatol. (1988) ; 3 : 139 - 142.
  39. Irshad M, Singh Shiwani, Ansari MA, Joshi YK. Viral Hepatitis in India : A report from Delhi. Glob. J. Health Sci. (2010) ; Vol. II (2) : 96 – 103.
  40. Irshad M. Interpretation of serological markers of hepatitis viruses. Trop. Gastroentrol. (1995) ; 16 : 4 - 10.

HEPATITIS - C and D

  1. Irshad M, Ansari MA, Singh A, Nag P, L Raghavendra, Singh Shiwani, S Sukhbir. HCV-genotypes: A review on their origin, global status, assay system, pathogenecity and response to treatment. Hepatogastroenterology. (2010) ; 57 : 1529 – 1538.
  2. Irshad M,Khushboo I.Hepatitis C virus (HCV) genotypes : An overview. Intl. J. Med. Sci. & Tech.(2008) ; 1 : 1 – 12.
  3. Irshad M, I Khushboo, Singh Shiwani, S Sukhbir. Hepatitis C Virus (HCV): Review of Immunological Aspects. Intl. Rev. Immunol. (2008) ; 27 : 497 - 517.
  4. Irshad M, Dhar I, Gupta S, Khushboo, Joshi YK. Correlation of hepatitis C virus (HCV) core protein expression with blood level of lipid and antioxidants in various forms of liver diseases. Hepatogastroenterology. (2007) ; 54 : 898 – 902.
  5. Irshad M, Dhar I, Khushboo, Shiwani Singh, S. Kapoor. Comparison of serological and nucleic acid based assays used to diagnose Hepatitis C virus (HCV) infection in acute and chronic liver diseases. Intl. J. Health Sci. (2007) ; 1 : 3 – 10.
  6. Irshad M, Dhar I. Hepatitis C virus (HCV) core protein : An update on its molecular biology, cellular functionsand clinical implications. Med. Prin. &3Prac. (2006) ; 15 : 405 – 416.
  7. Irshad M, Dhar I, Joshi YK. Significance of hepatitis C virus (HCV) core protein in the diagnosis of HCV infection in different liver diseases. J. Invest. Med. (2006) ; 54 : 478 – 483.
  8. Irshad M, Agarwal SK, Peter S. Occurrence of viral hepatitis during hemodialysis and renal transplantin CRF patients in Delhi. Intl. Med. J. (1999) ; 6 : 307 - 308.
  9. Irshad M,Agarwal SK. HCV infection in Delhi, India.Hepatol. Res. (1998) ; 11 : 129 - 132.
  10. Irshad M, Acharya SK. Hepatitis D virus (HDV) infection in severe forms of liver diseases in north India.Europ. J. Gastroenterol. Hepatol. (1996) ; 8 : 995 - 998.
  11. Irshad M, Gupta H. Hepatitis C virus. The Nat. Med. J. India. (1991) ; 4 : 20 - 23.
  12. Irshad M,Acharya SK, Joshi YK. Prevalence of hepatitis C virus antibodies in the general population and in selected groups of patients in Delhi. Ind. J Med. Res. (1995) ; 102 : 162 - 164.
  13. Irshad M, Kawatra M. Evolutionary changes in diagnosis of hepatitis C : A brief review of laboratory diagnosis. Ind. J. Pract. Doc. (2009) ; Vol. V : 62 – 66.
  14. Tandon BN, Gandhi BM, Irshad M,Acharya SK, Joshi YK, Anand AC. Delta Agent (virus-D) is present in India.Hep. Sci. Memo. Memo-H- 2336.
  15. Anand AC, Gandhi BM, Acharya SK, Irshad M, Joshi YK, Tandon BN. Hepatitis Delta Virus infection in India. J. Gastroenterol&Hepatol. (1988) ; 3 : 425 - 429.
  16. Gupta H, Irshad M, Joshi YK, Acharya SK, Tandon BN. Hepatitis C virus antibody in acute and chronic liver disease in India. Scand. J. Infect. Dis. (1990) ; 22 : 627.
  17. Tandon BN, Irshad M,Acharya SK, Joshi YK. Hepatitis C virus infection is the major cause of severe liver disease in India. Gastro. Japonica. (1991) ; 26 : 1460 - 1463.
  18. Agarwal SK, Irshad M, Dash SC. HCV infection during renal replacement therapy. Should we dialyse all HCV-positive patients on dedicated machines? Nephron. (1998) ; 79 : 479 - 480.
  19. Irshad M. DNA vaccines against hepatitis B and C viral infections : A brief overview. Trop. Gastroenterol. (1999) ; 20 : 64 - 67.
  20. Agarwal SK, Dash SC,Irshad M. Hepatitis C virus infection during haemodialysis in India. J. Assoc. Phys. of India (JAPI) (1999); 47 : 1139 - 1143.
  21. Aggarwal SK, Dash SC,Irshad M, Dinda A. Anti-HCV antibodies in primary glomerular diseases in India. Nephron. (2000) ; 84 : 290.
  22. Agarwal SK, Dash SC,Irshad M, Gupta S , Bhowmic D , Tiwari SC, Gularia S, Mehta SN. Impact of HCV infection on renal transplantation outcome in India- A single centre study. J. Assoc. Phys. of India (JAPI). (2000) ; 48 : 1155 - 1159.

HEPATITIS - E and G

 

  1. Irshad M , Peter S, Agarwal SK. Transmission of hepatitis E virus (HEV) infection via parenteral routes in Delhi. J. Int. Med. Sci. Acad. (2002) ; 15 : 75 - 78.
  2. Irshad M. Hepatitis G virus (HGV) infection : A brief overview. Intl. Med. J. (2000) ; 7 : 133 - 137.
  3. Irshad M. Hepatitis E Virus : An update on its molecular, clinical and epidemiological characteristics. Intervirology. (1999) ; 42 : 252 - 262.
  4. MathurP ,Arora NK, Panda SK, Kapoor SK, Jailkhani BL, Irshad M. Seroepidemiology of hepatitis E virus (HEV) in urban and rural children of north India. Ind. Pediat. (2001) ; 38 : 461- 475.
  5. Agarwal SK,Irshad M, Dash SC. Prevalence of antibodies against hepatitis E virus in hemodialysis patients in India. Nephron. (1999) ; 81 : 448.
  6. Irshad M. Hepatitis E virus : A global view of its seroepidemiology and transmission pattern. Trop. Gastroenterol. (1997) ; 18 : 45 - 49.

TORQUE TENO VIRUS (TTV)

  1. Irshad M,Mandal K, Singh Shiwani, Agarwal SK. Torque teno virus (TTV) infection in hemodialysis patients in North India. Intl. Urol. &Nephrol. (2010) ; 42 : 1077 – 1083.
  2. Irshad M,Shiwani Singh, Khushboo, Agarwal SK, Joshi YK. Torque Teno Virus (TTV) : its prevalence and isotypes in North India. World J. of Gastroenterol. (2008) ; 14 : 6044 – 6051.
  3. Irshad M, Joshi YK, Sharma Y, Dhar I. Transfusion transmitted virus (TTV) : A review on its molecular characteristics and role in medicine. World J. Gastroenterol. (2006) ; 12 : 5122 – 5134.
  4. Irshad M, Sharma Y, Dhar I, Singh J, Joshi YK. Transfusion-transmitted virus (TTV) in association with hepatitis A-E viral infections in various forms of liver diseases in India. World J. Gastroenterol. (2006); 12 : 2432 - 2436.

LIVER DISEASES

  1. Irshad M, Dubey R, Joshi YK. Impact of viral hepatitis on apo- and lipoprotein status in blood. Med. Prin. &Pract. (2007) ; 16 : 310 – 314.
  2. Irshad M, Choudhary PS, Joshi YK. Superoxide dismutase and total anti-oxidant levels invarious forms of liver diseases. Hepatol. Res. (2002) ; 23 : 178 - 184.
  3. Irshad M, Choudhary PS, Joshi YK, Etiological spectrum of viral hepatitis in various forms of liver diseases in Delhi, India. Intl. Med. J. (2001) ; 8 : 97 - 100.
  4. Irshad M, Peter S, Agarwal SK, Choudhary PS. Viral hepatitis in multiple blood transfused patients treated at a referral hospital of Delhi, India. Int. Med. J. (2001) ; 9 : 57 - 60.
  5. Irshad M,Acharya SK, Joshi YK, Tandon BN Role of fibronectin and complement in immuno-pathogenesis of acute and subacute hepatic failure. J. Gastroenterol. &Hepatol. (1994) ; 9 : 355 - 360.
  6. Acharya SK, Dasarathy S, Irshad M. Prospective study of plasma fibronectin in fulminant hepatitis : association with infection and mortality. J. Hepatol. (1995) ; 23 : 8 - 13.
  7. Acharya SK, Dasarathy S, Kumar TL, Irshad M et al. Fulminant hepatitis in a tropical population : Clinical course, Cause and early predictors of outcome. Hepatology. (1996) ; 23 : 1448 – 145.
  8. Irshad M. Oxidative stress in liver diseases. Trop. Gastroenterol. (2002) ; 23 : 6 - 8.
  9. Irshad M. Serum lipoprotein (a) levels in liver diseases caused by hepatitis. Ind. J. Med. Res. (2004) ; 120 : 542 - 546.
  10. Kar P, Gandhi BM, Irshad M, Gupta H, Tandon BN. Alpha-2 macroglobulin: An additional marker for diagnosis of hepatocellular carcinoma. J. Assoc. Phys. of India. (1987) ; 35 : 288 – 289.
  11. Anand AC, Irshad M,Acharya SK, Gandhi BM, Joshi YK, Tandon BN. Fibronectin in acute and subacute hepatic failure. J. Clin. Gastroenterol. (1989) ; 11 : 314 - 319.
  12. Acharya SK, Panda SK, Duphare H, Dasarathy S, Ramesh R, Jameel S, Nijhwan S, Irshad M, Tandon BN. Chronic hepatitis in a large Indian hospital. The Nat. Med. J. India. (1993) ; 6 : 202 - 206.
  13. Agarwal SK, Dash SC, Irshad M, Raju S, Singh
  14. R, Pandey RM. Prevalence of chronic renal failure in adults in India. Nephrol. Dialy. Transplant. (NDT). (2005) ; 20 : 1638 – 1642.
  15. Anand AC, Acharya SK, Irshad M, Gandhi BM, Joshi YK, Tandon BN. The significance of fibronectin in fulminant hepatic failure and implications of its replenishment. Med. J. Armed Forces. (1991) ; 47 : 89 - 95.

MEDICINE

  1. Irshad M, Sharma MP, Acharya SK. Plasma concentrations of fibronectin and C3d in patients with amoebic liver abscess. (ALA). J. Infect. (1992) ; 24 : 7 - 11.
  2. Gandhi BM, Gupta H, Irshad M, Chawla TC, Tandon BN. Cell -mediated immunity in amoebic liver abscess. Jap. J. Gastroenterol. (1984) ; 81.
  3. Thukral A, Lodha R, Irshad M, Arora NK. Performance of Pediatric Risk of Mortality (PRISM), Pediatric Index of Mortality (PIM), and PIM2 in a pediatric intensive care unit in a developing country. Pediatr. Crit. Care. Med. (2006) ; 7 : 356 – 361.
  4. S Sukhbir, Irshad M, Badhal S, Yadav K. Acute on chronic pancreatitis masking falciparum malaria : A Case Report. Global J. Health Sci. (2009) ; Vol. I : 123 – 125.
  5. Aggarwal P, Sharad S, Handa R, Dwiwedi SN, Irshad M. Comparison of nebulised magnesium sulphate and salbutamol combined with salbutamol alone in the treatment of acute bronchial asthma : a randomized study. Emerg. Med. J. (2006) ; 23 : 358 – 362.

IMMUNOLOGY

  1. Irshad M, Gandhi BM, Chaudhuri G, Tandon BN. Detection of Entamoebahistolytica in the pus of amoebic liver abscess by immunofluorescent technique. Ind. J. Med. Res. (1985) ; 81 : 575 - 579.
  2. Gandhi BM, Gupta H, Irshad M,Chawla TC, Tandon BN. Cell -mediated immunity in amoebic liver abscess. J. Trop. Med. &Hyg. (1986) ; 89 : 163 - 166.
  3. Gandhi BM, Bhargava DK, Irshad M,Chawla TC, Dubey A, Tandon BN. Enzyme-linked protein A: An ELISA for detection of IgG antibodies against Mycobacterium tuberculosis in intestinal tuberculosis. Intl. Symp. (1986) ; 105.
  4. Gandhi BM, Irshad M, Chawla TC, Tandon BN. Eznyme-linked protein-A: An ELISA for detection of amoebic antibody. Trans. Royal Soc. Trop. Med. &Hyg. (1987) ; 81 : 183 - 185.
  5. Chawla TC, Irshad M, Gandhi BM, Tandon BN. Immunological characterization of axenic Entamoebahistolytica related antigens. Ind. J. Med. Res. (1987) ; 86 : 457 - 461.
  6. Gandhi BM, Irshad M,Acharya SK, Tandon BN. The immunofluorescent detection of E. histolytica in pus using avidin-biotin system. J. Microbiol. Meth. (1987) ; 7 : 169 - 177.
  7. Gandhi BM, Irshad M,Acharya SK, Gupta BB, Tandon BN. Serological studies of Mycobacterium tuberculosis infection in north Indian population. J. Assoc. Phys. of India. (1987) ; 35 : 766 - 768.
  8. Gandhi BM, Irshad M,Acharya SK, Tandon BN. Amebic liver Abscess and circulating immune complexes of Entamoebahistolytica proteins. Am. J. Trop. Med. Hyg. (1988) ; 39 : 440 - 444.
  9. Acharya SK, Buch P, Irshad M, Joshi YK, Tandon BN. Outbreak of Dengue fever in Delhi. The Lancet. (1988) ; 332 (8626) : 1485 – 1486.
  10. Gandhi BM, Irshad M,Acharya SK, Tandon BN. A simple spot-test for circulating Entamoebahistolytica antigen-antibody complexes in patients with amoebic liver abscess. Ind. J. Med. Res. (1989) ; 89 : 177 - 183.
  11. Gandhi BM, Irshad M,Acharya SK, Samantray JC, Tandon BN. Use of affinity purified heterologous antibodies in an ELISA for the detection of EntamoebaHistolytica in feacal specimens. The Nat. Med. J. India. (1989) ; 2 : 223 - 227.
  12. Gandhi BM, Buch P, Sharma MP, Irshad M,Samantray JC. ELISA for anti-giardia IgM. The Lancet. (1989) ; 16 : 685.
  13. Rasool S, Behari M, Irshad M, Goyal V and Jailkhani BL. Antibodies against postsynaptic acetylcholine receptor and presynaptic membrane receptor in Myasthenia Gravis. Trends Med. Res. (2008) ; 3 : 64 – 71.
  14. Irshad M, Gandhi BM, Tandon BN. An improved ELISA technique to detect amoebic antibody in blood. Ann. Natl. Acad. Med. Sci. (India). (1986) ; 22 : 18 - 25.
  15. Gandhi BM, Bhargava DK, Irshad M,Chawla TC, Dube A, Tandon BN. Enzyme-linked protein-A: An ELISA for detection of IgG antibodies against Mycobacterium tuberculosis in intestinal tuberculosis. Tubercle. (1986) ; 67 : 219 - 224.

BIOCHEMISTRY

 

  1. Irshad M, Dubey R. Clinical Implications of apolipoproteins in different liver diseases. Int. Med. J. (2005); 4 : 161 - 167.
  2. Irshad M. Nitric Oxide:A unique molecule in clinical science. Int. Med. J. (2000); 8: 19 – 24.
  3. Irshad M, Sharma CB. Purification and properties of an alpha-amylase protein-inhibitor from Arachishypogaea seeds. Biochimica. etBiophysica. Acta. (1981) ; 659 : 326 - 333.
  4. Irshad M, Sharma CB. Sensitivity of plant alpha-amylases to calcium ions in vitro. Phytochemistry. (1981) ; 20 : 1205 -1209.
  5. Irshad M,Goel M, Sharma CB. Effect of Zn2+ on plant alpha -amylases in vitro. Phytochemistry. (1981) ; 20 : 2123- 2126.
  6. Irshad M, Khan MY, Salahuddin A. Salting-out behaviour of buffalo Immunoglobulin-G. Ind. J. Biochem. & Biophysics. (1981) ;18 : 264-268.
  7. Irshad M, Sharma CB. Aminoacid composition of alpha amylase protein inhibitor from Arachishypogaea seeds. Ind. J. Biochem. & Biophysics. (1985) ; 22 : 371 - 372.
  8. Irshad M, Sharma CB. Determination of Beta-Amylase in presence of alpha-amylase. Ind. J. Biochem. & Biophysics. (1986) ; 23 : 288 - 290.
  9. Irshad M, Chaudhuri PS. Oxidant-antioxidant system : Role and significance in human body. Ind. J. Exp. Biol. (2002); 40 : 1233 - 1239.
  10. Irshad M, Dubey R. Apolipoproteins and their role in different clinical conditions : An overview. Ind. J. Biochem. &Biophy. (2005);42:73– 80.
  11. Sharma CB, Goel M, Irshad M,Myoinositolhexaphosphate as a potential inhibitor of alpha-amylases.Phytochemistry. (1978);17:201-204.
  12. Salahuddin A, Irshad M,Qasim MA. Buffalo Immunoglobulin–G Effect of Lyotropic salts on its solubility. Ind. J. Biochem. & Biophysics. (1981) ; 18 : 317 - 321.
  13. Thomas S, Menon PSN, Khurana A, Irshad M, Khan MA. Mucopolysaccharidosis VI (Maroteaux-Lamy Syndrome). Ind. Pediat. (1983) ; 20 : 378 - 380.
  14. Gandhi BM, Irshad M, Manocha S, Tandon BN. Lipids and lipoproteins in amoebic liver abscess. Ind. J. Med. Res. (1986);83:594-599.
  15. Gandhi BM, Irshad M,Acharya SK, Tandon BN. NitroblueTetrazolium Test in the diagnosis of amoebic liver abscess. J. Assoc. Phys. of India. (1986) ; 34 : 711 - 713.
  16. Chawla YK, Irshad M,Chawla TC, Nundy S, Tandon BN. Urinary uropepsinogen in patients with dyspepsia. J. Assoc. Phys. of India. (1986) ; 34 : 851 - 852.
  17. Gandhi BM, Acharya SK, Irshad M, Gupta H, Chawla TC, Tandon BN. EntamoebaHistolytica: elevated Nitrobluetetrazolium reduction activity in polymorphs during amoebic liver abscess. Trans. Roy. Soc. Trop. Med. &Hyg. (1987) ; 81 : 283 - 285.
  18. Sharma MP, Irshad M,Verma SK. Alfa-Fetoprotein (AFP) in amoebic liver abscess. Ind. J. Med. Res. (1989) ; 90 : 127 - 130.
  19. Saraya A, Irshad M, Gandhi BM, Tandon RK. Plasma lipid profile in gall stone patients from north India. Trop. Gastroenterol. (1995) ; 16 : 16 - 21.
  20. Sharma Y, Bashir S,Irshad M, Gupta SD, Dogra TD. Effects of acute dimethoateadministration on antioxidant status of liver and brain of experimental rats. Toxicology. (2005) ;206 : 49 - 57.
  21. Sharma Y, Bashir S, Irshad M, Nag TC, Dogra TD. Dimethoate-induced effects on antioxidant status of liver and brain of rats following subchronic exposure. Toxicology. (2005) ; 215 : 173 - 181.
  22. Bashir S, Sharma Y,Irshad M, Gupta SD, Dogra TD. Arsenic induced apoptosis in rat liver following repeated exposure for 60 days. Toxicology. (2006) ; 217 : 63 – 70.
  23. Bashir S, Sharma Y, Irshad M, Gupta SD, Dogra TD. Arsenic induced cell death in liver & brain of experimental rats. Bas. &Clin. Pharmacol. &Toxicol. (2006) ; 98 : 38 – 43.
  24. Rasool S, Jailkhani BL, Behari M, Suhail S, Shabirul H and Irshad M. Purification of Beta Bungarotoxin (b-Bgtx) Binding Protein from Human Cadaver Skeletal Muscle. J. Med. Sci. (2007) ; 7 : 195 – 202.
  25. Rasool S, Jailkhani BL, Irshad M,Behari M, Goel V. Alpha-bungarotoxin (a-Bgtx) and beta-bungarotoxin (b-Bgtx) binding activities in human cadaver brain. Arch. Med. Sci. (2007) ; 3 : 93 – 101.
  26. Qurashi R, Lakshmy R, Prabhakaran D, Irshad M,Mukhopadhyay AK, Jailkhani B. Effect of storage temperature on cholesterol measurement from dried blood. Ind. J. Med. Res. (2007) ; 126 : 228 – 229.

 

RECENT PUBLICATIONS

  1. Irshad M, Khushboo, Prashant Nag. Insulin resistance (IR) in liver diseases.Macedonian Journal of Medical Sciences (2011) ; 4 (2) : 201 - 209.
  2. Irshad M, Ansari MA, SinghShiwani, Joshi YK. Hepatitis C virus (HCV)-core expression : Role of serum core-protein in diagnosis of HCV infection and its relation with oxidative stress & liver steatosis. ELIXIR Virus Research (2011) ; 35 : 2802 – 2808.
  3. Irshad M, Ansari MA, Singh Shiwani, Nag P. Hepatic cell injury during HCV infection : A review on the role of various host factors. ELIXIR Virus Research (2011) ; 37 : 3864 – 3870.
  4. Ansari MA, Raghavendra L, Irshad M. HCV-core region : Its significance in HCV-genotyping and type dependent genomic expression. Macedonian Journal of Medical Sciences (2012) ;5(1):30-39.999
  6. Irshad M, AsifIqbal, M.A. Ansari, Raghavendra L. Relation of insulin resistance (IR) with viral etiology and blood level of cytokines in patients with liver diseases. Global Advanced Research Journal of Medicine & Medical Sciences (2013) ; 2 : 075 – 083.
  7. Rasool S, Behari M, Goyal V, Irshad M and Jailkhani BL. Presynaptic membrane receptor in human brain. Indian J. Clinical Biochemistry (2013) ; 28 : 124 – 135.
  8. Ansari MA, Irshad M. Expression of the full-length HCV core subgenome from HCV gentoype-1a and genotype-3a and evaluation of the antigenicity of translational products. European Journal of Gastroenterology &Hepatology(2013) ;25 : 806 – 813.
  9. Singh S, Singh A, Mankotia DS, Luthra K, Irshad M. Expression of TTV-ORF2 protein for detection of anti- TTV IgG antibodies in human sera. Advances in Infectious Diseases (2013) ; 3 : 223 – 229.
  11. Irshad M, M.A. Ansari, Khushboo I, Raghavendra L. A novel single step multiplex real time PCR assay for simultaneous quantification of hepatitis virus A,B, C & -E in serum. Journal of Gastroenterology & Hepatology (2013) ;28 : 1869 – 1876.
  12. Irshad M, Mankotia DS, Khushboo I. An insight into the diagnosis and pathogenesis of hepatitis C virus infection. World J. Gastroenterology (2013) ; 19(44): 7896-7909.
  13. Mankotia DS, Irshad M. Cloning and expression of N22 region of TTV genome and use of peptide in developing immunoassay for TTV antibodies. Virology Journal (2014) ; 11 : 96.
  14. Rasool S, Goyal V, Irshad M and Jailkhani BL. Alpha and beta bungarotoxin binding proteins in human cadaver muscle. Journal of Musculoskeletal Research (2014) ; 17 : 1450005.
  15. Sethuraman G, Sreenivas V, Yenamandra VK, Gupta N, Sharma VK, Marwaha RK, Bhari N, Irshad M, Kabra M and Thulkar S. Threshold levels of 25-hydroxyvitamin D and parathyroid hormone for impaired bone health in children with congenital ichthyosis and type IV and V skin. British Journal of Dermatology (2014) ; 172: 208–214.
  16. Irshad M, Gupta P, Mankotia DS, Ansari MA. Multiplex qPCR for serodetection and serotyping of hepatitis viruses: A brief review. World J. Gastroenterology (2016); 28(20): 4824-4834.
  17. Singh A, Mankotia DS, Irshad M. A single-step multiplex quantitative real time polymerase chain reaction assay for hepatitis C virus genotypes.J Translation Internal Med (2017); 5: 34-42.
  18. Yoganathan S, Bagga A, Gulati S, Toteja GS, Hari P, Sinha A, Pandey RM, Irshad M. Prevalence and predictors of peripheral neuropathy in non-diabetic children with chronic kidney disease. Muscle Nerve. 2017 Nov 29. doi: 10.1002/mus.26027. PMID: 29193154
  19. Irshad M, Gupta P, Khushboo I. Molecular Basis of Hepatocellular Carcinoma induced by HCV Infection. World J Hepatol 2017 December 28; 9(36): 1305-1314
  20. Bhatia V, Dhawan A, Arora NK, Mathur P, Das MK, Irshad M. Urinary potassium loss in children with acute liver failure and acute viral hepatitis. J PediatrGastroenterolNutr. 2013 Jul;57(1):102-8. doi: 10.1097/MPG.0b013e31828fc8ea. PMID: 23471182150.
  21. Mankotia DS, Irshad M. Development of an immunoassay for detection of Torque teno virus (TTV) antibodies using the N22 expression product from TTV genotype 2. Intervirology (2018); 60: 207 – 216. DOI: 10.1159/000487481
  22. Irshad M, Mankotia DS, Khushboo I, and Gupta P. Viral hepatitis in India: Current Status. Gastroenterol HepatolEndosc2018; 3(1): 1-5.DOI: 10.15761/GHE.1000153
  23. Irshad M, Gupta P, Khushboo I. Molecular targeting of antiviral drugs used against HCV infection.Hepatoma Res 2018;4:23. DOI: 10.20517/2394-5079.2018.25

COMMUNICATION

 

  1. Irshad M, Gupta P, Khushboo I. Immunopathogenesis of Liver Injury during HCV Infection. Microbial Pathogenesis (2018).
  2. Gupta P, Khushboo I,Irshad M. Molecular Basis of Transformation of a Normal Cell to the Malignant Cell. Tumor & Microenvironment (2018).

CHAPTER IN BOOKS

 

  1. Irshad M. Laboratory diagnosis of viral hepatitis. Proceedings of ‘Hepatitis and Renal Medicine’ 1999 ; 1 : 9 – 15.
  2. Book on Gen. Surgery (Edition-1): Chapter on laboratory parameters by Irshad M.
  3. Book on Gen. Surgery (Edition-2): Chapter ofrn laboratory parameters by Irshad M.
  4. Irshad M, Mankotia DS, Khushboo I (2014). “An insight into the diagnosis and pathogenesis of hepatitis C virus infection” In (First Edition), World Clinical Gastroenterology (2549 - 2562). Pleasanton, CA: Baishideng Publishing Group.

 

CITATIONS

  1. Many of my research publications on ‘Seroepidemiology of viral Hepatitis’ have been cited as references in important reference books on Hepatitis . Notable books are :
  2. “ Viral Hepatitis “ edited by AJ Zuckerman ; 1998 , 2nd Edition : Churchil Livingstone.
  3. “ Hepatitis B in India : Problem and Prevention “ edited by SK Sarin and AK Singal 1996 ; CBS Publications.
  4. Blackwell publishers:Nominated as the reviewer for the articles of Blackwell Publishers & Elsevier Publishers.
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