Ongoing Research

Research

Funded Research Projects (Ongoing)

1. Comparison of Alpha Emitting 225Ac-DOTATATE Versus Beta Emitting 177Lu-DOTATATE Therapy in Advanced End-stage Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET) Patients, Chandrasekhar Bal, ICMR-ICRC, 5 years, 2019-24, Rs 49,00,000/- per year.

2. A Prospective, Randomized, Controlled, Open-label, Multicenter Trial to Evaluate Efficacy, Safety and Patient reported Outcomes of Peptide Receptor Radionuclide Therapy (PRRT) with Lutetium (177Lu) Edotreotide compared to Best Standard of Care in Patients with Well-differentiated Aggressive Grade 2 and Grade 3, Somatostatin Receptor-positive (SSTR+), Neuroendocrine Tumors of Gastro-Enteric or Pancreatic Origin (COMPOSE), Chandrasekhar Bal, ITM, 5 years, December 2021 to Ongoing, Rs 30,00,000/- per year.

3. A randomized, double-blinded, placebo-controlled phase III study to evaluate the efficacy and safety of dabrafenib plus trametinib in previously treated patients with locally advanced or metastatic, radioactive iodine refractory BRAFV600E mutation-positive differentiated thyroid cancer, Chandrasekhar Bal, NOVARTIS, 5 years, 2022 to ongoing, Rs 25,00,000/- per year.

4. Efficacy of low dose lenvatinib as adjuvant therapy to radioiodine in advanced metastatic differentiated thyroid cancer: A randomized control trial, Chandrasekhar Bal, Intramural (AIIMS), 1 + 1 year, 2022 to ongoing, Rs 10,00,000.

5. Diagnostic Accuracy of 68GaPSMA-11 PET/CT and Conventional Imaging for Initial Staging of Intermediate and High-risk Prostate Cancer Patients (the PROCA Study), Dr Rakesh Kumar funded by the International Atomic Energy Agency (IAEA), Vienna, Austria, 4 years, 2022-2025, 6000 Euros per year.

6. International study on imaging in Cardio-Oncology Study (iCOS), Dr Chetan D Patel, International Atomic Energy Agency (IAEA), 5 years, September 2019 -ongoing, 25,000 Euros.

7. Utility of Radiolabelled Antibiotics as Imaging Agents in Establishment of a Decision Support Algorithm in Patients with Pyrexia of Unknown Origin (PUO) Caused by Infection and its Impact on Short Term and Long Term Clinical Outcomes, Dr Nishikant A Damle, ICMR, 2019-2023, 4 years, Rs 33 lakhs.

8. Role of 177Lu-PSMA therapy in patients with Adenoid Cystic Carcinoma, Dr Shamim A. Shamim, Intramural Funding, 1+1 years, 2021-2023, Rs 10,00,000.

9. Comparison of Re-188-HDD Lipiodol Transarterial Radionuclide Therapy (TART) with Re-188-DEDC Lipiodol TART in the Management of advanced Hepatocellular Carcinoma: A Randomized control trial, Dr Shamim A Shamim, ICMR, 3 years, 2019-2023, Rs 47,56,910.

10. IAEA Transthyretin Amyloid Cardiomyopathy Study (iTAC study), Dr Khangembam Bangkim Chandra, International Atomic Energy Agency (IAEA), Vienna, Austria, 4 years, 2022-2025, 20,000 Euros

Funded Research Projects (Completed)

1. Mutation spectrum of BRAF gene among patients with Papillary Thyroid Carcinoma: A patho-genetic study in Indian population, Dr Chandrasekhar Bal, ICMR, 4 years, 2018-22, Rs 35,00,000 per year.

2. Prospective Single Arm Post Marketing Phase IV Study to Assess the Safety and Efficacy of Lenvatinib in Subjects with Locally Recurrent or Metastatic, Progressive, Radioiodine Refractory Differentiated Thyroid Cancer”. PHASE IV FDA TRIAL, Dr Chandrasekhar Bal, CLIANTHA RESEARCH LTD, until all patient attain an event, 2018- 22, No funds for manpower Funds directly to patients.

3. Use of PET-CT with Gallium-68 Labeled Prostrate Specific Membrane Antigen in the Diagnosis and Follow-up of Patients with Prostate Cancer”, Dr Rakesh Kumar, International Atomic Energy Agency (IAEA), Vienna, Austria, 5 years, 2017-2022, 5000 Euros per year.

4. Gastric Emptying Scintigraphy using a Standard Vegetarian Meal: Establishment of Reference Values in Post-Sleeve Gastrectomy Patients on Mid-Term Follow-Up, Dr Khangembamn Bangkim Chandra, AIIMS, New Delhi, 2 years, 2021-2023, Rs 2.0 lakhs.

Details of prior research projects are available in the annual reports available on the institute’s website. Please visit the AIIMS website and go to “About Us  Annual Reports”.

Research Publications

Details of prior research publications are available in the annual reports available on the institute’s website. Please visit the AIIMS website and go to “About Us  Annual Reports”.