DR. SACHIN KUMAR
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SACHIN KUMAR
Personal Details
Date of Birth 2nd May, 1982
Address Room No. 401, 4th Floor, Dept. of Medical Oncology, Dr. BRA Institute Rotary Cancer Hospital, AIIMS, New Delhi-110029
Tel. No. +91-11-29575401 (Office)
E-mail यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए. ; यह ईमेल पता spambots से संरक्षित किया जा रहा है. आप जावास्क्रिप्ट यह देखने के सक्षम होना चाहिए.
Educational Qualifications
Degree |
Institute/University/College |
Specialization / Subject |
Year(s) |
PhD |
Dept. of Medicine, All India Institute of Medical Sciences, New Delhi, India |
Title: Clinical Implications of Circulating DNA and Protein Markers in Lung Cancer
Chief Guide: Prof. (Dr.) Randeep Guleria |
July 2005 - June 2010 |
MSc |
Maharshi Dayanand University, Rohtak, Haryana, India |
Biotechnology |
2002-2004 |
BSc |
Vaish PG College, Bhiwani, Haryana, India |
Zoology, Botany, Chemistry |
1999-2002 |
Academic / Research Experience
Designation |
Institute/University |
Duration |
Role |
Scientist II |
Dept. of Medical Oncology, Dr. BRA IRCH, All India Institute of Medical Sciences, New Delhi, India |
16th Sept. 2016 - till date |
Research and patient care services |
Assistant Professor |
Amity Institute of Biotechnology & Amity Institute of Molecular Medicine & Stem Cell Research, Amity University Uttar Pradesh (Noida), India |
12th March 2012 - 15th Sept. 2016 |
Research and teaching |
Postdoctoral Fellow |
Dept. of Human & Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia, USA |
19th Oct. 2010 – 28th Jan. 2012 |
Research |
Senior Research Fellow |
National Institute of Cancer Prevention & Research (Formerly ICPO), Noida, Uttar Pradesh, India |
5th May 2010 - 11th Oct. 2010 |
Research |
Research Projects: Ongoing
Sr. No. |
Project |
Funding agency |
Grant amount |
Duration (From – To) |
Role |
1 |
Elucidating the role of circular RNA circLIFR in the pathogenesis of small cell lung cancer |
SERB, DST, New Delhi |
~ 41 lakhs |
21/01/2022 – 20/01/2025 |
PI (Collaborator: Dr. Ishaan Gupta, IIT-Delhi) |
2 |
Elucidation of the role of long non-coding RNA-Ginir as a biomarker in lung tumorigenesis |
DBT, New Delhi |
~89 lakhs |
19/08/2021 – 18/08/2024 |
PI (Collaborator: Dr. Manas Santra, NCCS, Pune) |
3 |
Global profiling of circular RNAs in small cell lung cancer: a pilot study |
AIIMS, New Delhi |
10 lakhs |
29/10/2020 – 28/10/2022 |
PI |
Completed
Sr. No. |
Project |
Funding agency |
Grant amount |
Duration (From – To) |
Role |
1 |
Identification of a dysregulated circulating miRNA signature in non-small cell lung cancer |
SERB, New Delhi |
~23 lakhs |
09/09/2014 – 08/12/2017 |
PI (Young Scientist Scheme) |
2 |
Investigating the efficacy of microRNAs as molecular marker in cytogenetically normal pediatric acute myeloid leukemia |
DBT, New Delhi |
~65 lakhs |
06/02/2015 –05/08/2018 |
Project coordinator and PI (Co-PI: Dr. Sameer Bakhshi) |
3 |
Elucidating the mechanism of regulation of PD-L1 expression in lung cancer – role of epigenetics and copy number alterations |
AIIMS, New Delhi |
10 lakhs |
18/09/2017 –17/09/2019 |
PI |
4 |
The clinical significance of HOTAIR and HOTAIRM1 long non-coding RNAs in pediatric acute myeloid leukemia |
AIIMS, New Delhi |
10 lakhs |
30/08/2017 –29/08/2019 |
Co-investigator |
5 |
Liquid Biopsy: An exploratory study on exosomes based diagnostics for lung cancer |
AIIMS-IIT Delhi |
20 lakhs |
11/2018 –11/2020 |
Co-investigator |
6 |
Clinical significance of cell-free DNA in intraoperative pleural lavage fluid and plasma in patients undergoing pulmonary metastasectomy |
AIIMS, New Delhi |
10 lakhs |
09/2018 –09/2020 |
Co-investigator |
7 |
Evaluation of regulation of programmed death-ligand 1 (PD-L1) expression by microRNA in lung cancer |
ICMR, New Delhi |
~47 lakhs |
16/08/2019 – 15/08/2022 |
PI |
8 |
The clinical significance of UCA1 long non-coding RNA in pediatric acute myeloid leukemia |
AIIMS, New Delhi |
10 lakhs |
29/10/2020 – 28/10/2022 |
Co-investigator |
Publications[Total Citations: 1315; h-index: 16 (Stats from Google Scholar)]
- Singh S, Pathak A, Kumar S, Malik PS, Elangovan R. Rapid immunomagnetic co-capture assay for quantification of lung Cancer associated exosomes. Journal of Immunological Methods 2022; 508: 13324. IF: 2.287. https://doi.org/10.1016/j.jim.2022.113324
- Tyagi A, Singh S, Pandey V, Kumar S, Malik PS, Elangovan R. SNC-TIRS: Label-free single nanoparticle characterization system based on total internal reflection scattering signal. Particle & Particle Systems Characterization 2022 (In Press). IF: 3.467. https://doi.org/10.1002/ppsc.202200130
- Budhraja A, Basu A, Gheware A, Abhilash D, Rajagopala S, Pakala S, Sumit M, Ray A, Arulselvi S, Mathur P, Nambirajan A, Kumar S, Gupta R, Wig N, Trikha A, Guleria R, Sarkar C, Gupta I, Jain D. Molecular signature of postmortem lung tissue from COVID-19 patients suggests distinct trajectories driving mortality. Dis Model Mech. 2022; 15(5):dmm049572. Citation: 1; IF: 5.732. doi: 10.1242/dmm.049572
- Kumar S*, Saikia J, Sharawat SK, Malik PS, Kumar S, Mohan A. Analysis of miR-375-3p, miR-197-3p, and miR-15a-5p expression and their clinical relevance as biomarkers in lung cancer. Technol Cancer Res Treat. 2022; 21:1-11. Citation: 1; IF: 2.876. https://doi.org/10.1177%2F15330338221080981
- Kumar S*, Pandey M, Mir IA, Mukhopadhyay A, Sharawat SK, Jain D, Saikia J, Malik PS, Kumar S, Mohan A. Evaluation of the programmed death-ligand 1 mRNA expression and immunopositivity and their correlation with survival outcomes in Indian lung cancer patients. Human Cell 2022; 35(1):286-298. IF: 4.374. https://doi.org/10.1007/s13577-021-00647-4
- Pandey M, Mukhopadhyay A, Sharawat SK, Kumar S*. Role of microRNAs in regulating cell proliferation, metastasis and chemoresistance and their applications as cancer biomarkers in small cell lung cancer. Biochim Biophys Acta Rev Cancer 2021; 1876(1):188552. Citation: 15; IF: 11.414. https://doi.org/10.1016/j.bbcan.2021.188552.
- Aftab M, Poojary SS, Seshan V, Kumar S, Agarwal P, Tandon S, Zutschi V, Das BC. Urine miRNA signature as a potential non-invasive diagnostic and prognostic biomarker in cervical cancer. Sci Rep 2021; 11:10323. Citation: 22; IF: 4.996. https://doi.org/10.1038/s41598-021-89388-w.
- Kumari S, Arora M, Singh J, Chauhan SS, Kumar S, Chopra A. L-Selectin expression is associated with inflammatory microenvironment and favourable prognosis in breast cancer. 3Biotech 2021; 11:38. Citation: 4; IF: 2.893. https://doi.org/10.1007/s13205-020-02549-y.
- Kumar S*, Pandey M, Sharawat SK. Biological functions of long noncoding RNAs and circular RNAs in small-cell lung cancer. Epigenomics 2020; 12(19):1751-1763. Citation: 4; IF: 4.357. https://doi.org/10.2217/epi-2020-0214.
- Gaur V, Chaudhary S, Agarwal S, Sharawat SK, Bakhshi S, Sharma P, Kumar S*. miR-4772-5p and miR-196b as potential prognostic biomarker in pediatric core binding factor acute myeloid leukemia. Int J Med Res Health Sci 2020; 9(12):104-115. IF: 0.11
- Kumar S*, Sharawat SK, Ali A, Gaur V, Malik PS, Pandey M, Kumar S, Mohan A, Guleria R. Differential expression of circulating serum miR-1249-3p, miR-3195 and miR-3692-3p in non-small cell lung cancer. Human Cell 2020; 33:839-849. Citation: 11; IF: 4.374. 10.1007/s13577-020-00351-9.
- Kumar S*, Sharawat SK, Ali A, Gaur V, Malik PS, Kumar S, Mohan A, Guleria R. Identification of differentially expressed circulating serum microRNA for the diagnosis and prognosis of Indian non-small cell lung cancer patients. Curr Probl Cancer 2020; 44(4): 100540. Citation: 35; IF: 2.367. https://doi.org/10.1016/j.currproblcancer.2020.100540
- Gaur V, Chaudhary S, Tyagi A, Agarwal S, Sharawat SK, Sarkar S, Singh H, Bakhshi S, Sharma P, Kumar S*. Dysregulation of miRNA expression and their prognostic significance in pediatric cytogenetically normal acute myeloid leukemia. British J of Hematology 2020; 188(6): e90-e94. Citation: 4; IF: 8.615. https://doi.org/10.1111/bjh.16375
- Bhat AA, Younes SM, Raza SS, Zarif L, Nisar S, Ahmed I, Mir R, Kumar S, Sharawat SK, Hashem S, Elfaki I, Kulinski M, KuttiKrishnan, S, Prabhu KS, Khan AQ, Yadav SK, El-Rifai W, Zargar MA, Zayed H, Haris M, Uddin S. Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance. Mol Cancer 2020; 19(1): 57. Citation: 55; IF: 41.444. https://doi.org/10.1186/s12943-020-01175-9
- Mann M, Kumar S, Sharma A, Chauhan SS, Bhatla N, Kumar S, Bakhshi S, Gupta R, Kumar L. PARP-1 inhibitor modulate β-catenin signaling to enhance cisplatin sensitivity in cancer cervix. Oncotarget 2019; 10(42): 4262-4275. Citation: 16; IF: 5.168. https://doi.org/10.18632/oncotarget.27008
- Khurana S, Kumar S, Guleria R, Choudhury S, Gaur V, Saha B, Bose S. Molecular signatures of microRNA in obesity associated obstructive sleep apnea in middle-aged adults. Int J Med Res Health Sci 2019; 8(11): 57-66. IF: 0.11
- Khurana S, Sharda S, Saha B, Kumar S, Guleria R, Bose S. Canvassing the etiology, prognosis and molecular signatures of obstructive sleep apnea. Biomarkers 2019; 24:1-16. Citation: 8; IF: 2.663. https://doi.org/10.1080/1354750X.2018.1514655
- Kumar S*, Sharawat SK. Epigenetic regulators of programmed death-ligand 1 expression in human cancers. Translational Research 2018; 202:129-145. Citation: 30; IF: 10.171. https://doi.org/10.1016/j.trsl.2018.05.011.
- Kumar S*, Gaur V, Khurana S, Bose S, Kiran M, Sharawat SK. Proteomics – An update on recent tools and techniques. EC Proteomics and Bioinformatics 2018 February 8; 2(2):57-73.
- Ali A, Kumar S, Kakaria VK, Mohan A, Luthra K, Upadhyay AD, Guleria R. Detection of promoter DNA methylation of APC, DAPK, and GSTP1 genes in tissue biopsy and matched serum of advanced stage lung cancer patients. Cancer Invest 2017; 35(6):423-430. Citation: 6; IF: 2.368. https://doi.org/10.1080/07357907.2017.1309547
- Kumar S*, Bakhshi S. The diagnostic and prognostic role of microRNAs in pediatric acute myeloid leukemia – a review. Indian Journal of Medical Research 2016; 144(6):807-814.Citation: 2; IF: 5.274. 10.4103/ijmr.IJMR_220_15
- Singh DK, Bose S, Kumar S*. Role of microRNA in regulating cell signaling pathways, cell cycle, and apoptosis in non-small cell lung cancer. Curr Mol Med 2016; 16(5): 474-486. Citation: 14; IF: 2.616. 10.2174/1566524016666160429120702
- Singh DK, Bose S, Kumar S*. Regulation of expression of microRNAs by DNA methylation in lung cancer. Biomarkers 2016; 21(7):589-599. Citation: 15; IF: 2.663. https://doi.org/10.3109/1354750X.2016.1171906
- Bose S, Ganguly S, Kumar S, Bookckfer FR. A Pit-1 binding site adjacent to E-Box 133 in the rat PRL promoter is necessary for pulsatile gene expression activity. Neurochem Res 2016; 41(6):1390-1400.Citation: 4; IF: 4.414. https://doi.org/10.1007/s11064-016-1843-y
- Tilak AR, Kumar S, Pant MC, Mathur N, Kumar A. Polymorphism Arg72Pro of p53 confers susceptibility to squamous cell carcinoma of lungs in a north Indian population. DNA Cell Biol 2013; 32(2):66-72.Citation: 9; IF: 3.55. https://doi.org/10.1089/dna.2012.1792
- Quinn BA, Dash R, Azab B, Sarkar, S, Das SK, Kumar S, Oyesanya RA, Dasgupta S, Dent P, Grant S, Rahmani M, Curiel DT, Dmitriev I, Hedvat M, Wei J, Wu B, Stebbins JL, Reed JC, Pellecchia M, Sarkar D, Fisher PB. Targeting Mcl-1 for the therapy of cancer. Expert Opin Investig Drugs 2011; 20(10):1397-1411. Citation: 229; IF: 6.498. https://doi.org/10.1517/13543784.2011.609167
- Tilak AR, Kumar S, Jain M, Pant MC, Das BC, Guleria R, Mittal B, Mathur R, Kumar A. Association of functionally important polymorphism of microsomal epoxide hydrolase gene (EPHX1) with lung cancer susceptibility. Cancer Invest 2011; 29(6):411-418. Citation: 29; IF: 2.368. https://doi.org/10.3109/07357907.2011.587070
- Kumar S, Guleria R, Singh V, Bharti AC, Mohan A, Das BC. Efficacy of plasma TGF-β1 level in predicting therapeutic efficacy and prognosis in patients with advanced non-small cell lung cancer. Cancer Invest 2011; 29(3):202-207. Citation: 29; IF: 2.368. https://doi.org/10.3109/07357907.2010.543208
- Kumar S, Guleria R, Singh V, Bharti AC, Mohan A, Das BC. Efficacy of circulating plasmaDNA as a diagnostic tool for advanced non-small cell lung cancer and its predictive utility for survival and response to chemotherapy. Lung Cancer 2010; 70(2):211-217. Citation: 55; IF: 6.081. https://doi.org/10.1016/j.lungcan.2010.01.021
- Kumar S, Guleria R, Singh V, Bharti AC, Mohan A, Das BC. Plasma DNA level inpredicting therapeutic efficacy in advanced non-small cell lung cancer. Eur Respir J 2010; 36(4):885-892. Citation: 49; IF: 33.795. https://doi.org/10.1183/09031936.00187909
- Kumar S, Guleria R, Singh V, Mohan A, Bharti AC, Das BC. Lack of utility of plasmaTNF-alpha level in predicting therapeutic efficacy in patients with advanced non-small cell lung cancer. Cytokine 2010; 51(3):245-248. Citation: 4; IF: 3.926. https://doi.org/10.1016/j.cyto.2010.05.007
- Kumar S, Guleria R, Mohan A, Singh V, Ali A, Bharti AC, Das BC. Utility of plasmatumour necrosis factor-alpha and transforming growth factor-beta1 as predictors of survival and treatment outcome in advanced non-small cell lung carcinoma. Biomarkers 2010; 15 (5):446-453. Citation: 10; IF: 2.663. https://doi.org/10.3109/1354750X.2010.485699
- Kumar S, Guleria R, Singh V, Bharti AC, Mohan A, Das BC. Plasma nucleosome levelsmight predict response to therapy in patients with advanced non-small cell lung cancer. Clin Lung Cancer 2010; 11(1):36-44.Citation: 30; IF: 4.84.https://doi.org/10.3816/CLC.2010.n.006
- Kumar S, Guleria R, Singh V, Bharti AC, Mohan A, Das BC. Efficacy of plasma vascularendothelial growth factor in monitoring first-line chemotherapy in patients with advanced non-small cell lung cancer. BMC Cancer 2009; 9(1):421.Citation: 19; IF: 4.638. https://doi.org/10.1186/1471-2407-9-421
- Singh VK, Chandra S, Kumar S, Pangtey G, Mohan A, Guleria R. A common medical error: lung cancer misdiagnosed as sputum negative tuberculosis. Asian Pac J Cancer Prev 2009; 10(3):335-338. Citation: 75; IF: 1.23; PMID: 19640168
- Kumar S, Mohan A, Guleria R. Prognostic implications of circulating anti-p53 antibodies inlung cancer-a review. Eur J Cancer Care 2009; 18(3):248-254. Citation: 41; IF: 2.328. https://doi.org/10.1111/j.1365-2354.2008.01019.x
- Mohan A, Singh P, Kumar S, Mohan C, Pathak AK, Pandey RM, Guleria R. Effect of change in symptoms, respiratory status, nutritional profile and quality of life on response to treatment for advanced non-small cell lung cancer. Asian Pac J Cancer Prev 2008; 9(4):557-562. Citation: 66; IF: 1.23; PMID: 19256738
- Pathak AK, Bhutani M, Kumar S, Mohan A, Guleria R. Circulating cell-free DNA in plasma/serum of lung cancer patients as a potential screening and prognostic tool. Clin Chem 2006; 52(10):1833-1842. Citation: 274; IF: 12.167. https://doi.org/10.1373/clinchem.2005.062893
- Kumar S, Mohan A, Guleria R. Biomarkers in cancer screening, research and detection:present and future: a review. Biomarkers 2006; 11(5):385-405. Citation: 152; IF: 2.663.
https://doi.org/10.1080/13547500600775011
- Kumar S, Singh V, Chandra S, e. Serum vascular endothelial growth factor is related to systemic oxidative stress in patients with lung cancer. Lung Cancer 2009; 65(2):254. IF: 6.081 (Letter to Editor).
(* denotes articles published as a corresponding author)
Abstracts
- Chitikela SD, Malik PS, Khurana S, Kumar S, Pushpam D, Mohan A, Jain D. Familial aggregation in non-small cell lung cancer - an observational study (EP03.01-006). J Thor Oncol 2022; 17(9):S239.
- Saikia J, Malik PS, Kumar S, Jain D, Madam K, Bharati SJ, Deo S, Kumar S. Can cell-free DNA in pleural lavage serve as a predictive and prognostic biomarker among surgically treated non-small cell cancers of the lung (NSCLC): a pilot study. Lung Cancer 2022; 165 (S1): S2.
- Saikia J, Malik PS, Kumar S, Jain D, Madam K, Bharati SJ, Deo S, Kumar S. Predictive and prognostic value of cell-free DNA in plasma and pleural lavage among surgically treated adenocarcinomas of the lung (ADCL). Annals of Oncology 2021; 32 (S6): S1348.
- Kumar S, Sharawat SK, Ali A, Malik PS, Mohan A, Guleria R. Diagnostic and prognostic utility of differentially expressed circulating microRNAs in Indian NSCLC patients (EP1.03-20). J Thor Oncol 2019; 14 (10S): S960-S961.
- Malik PS, Yadav A, Jain D, Pathy S, Mohan A, Khurana S, Kumar S. Pemetrexed-carboplatin versus paclitaxel (weekly)-carboplatin as first line chemotherapy in advanced non-squamous NSCLC (P1.01-02). J Thor Oncol 2019; 14 (10S): S354-355.
- Verma S, Malik PS, Yadav A, Jain D, Khurana S, Kumar S. Thymidylate synthase and folate receptor alpha expression as potential biomarkers for efficacy of pemetrexed in NSCLC (EP1.01-71). J Thor Oncol 2019; 14 (10S): S939.
- Gaur V, Chaudhary S, Tyagi A, Bakhshi S, Sharma P, Kumar S. Differential expression of various miRNAs in pediatric cytogenetically normal acute myeloid leukemia (CN-AML). Annals of Oncology 2019; 30 (Supplement 5): v50-v51.
- Gaur V, Chaudhary S, Tyagi A, Bakhshi S, Sharma P, Kumar S. Dysregulated microRNA expression in pediatric cytogenetically normal acute myeloid leukemia patients (#1798). Proceedings of the American Association for Cancer Research 2019; 60:460-461.
- Kumar S, Ali A, Guleria R. Identification of differentially expressed circulating miRNAs in the serum of NSCLC patients using next generation sequencing (P2.01-011). J Thor Oncol 2017; 12 (1S): S789-S790.
- Ali A, Kumar S, Kakaria V, Mohan A, Luthra K, Upadhyay A, Guleria R. Detection of promoter DNA methylation of APC, DAPK, and GSTP1 genes in tissue biopsy and matched serum of advanced stage lung cancer patients (P2.01-007). J Thor Oncol 2017; 12 (1S): S787.
- Guleria R, Mohan A, Kumar S, Ali A, Kumar A. Survival outcomes in advance non-small cell lung cancer – a developing country scenario (P4421). Eur Respir J 2011; 38 (Suppl. 55): 815S.
- Das BC, Bharti AC, Mohan A, Guleria R, Kumar R, Kumar S. Vascular endothelial growth factor (VEGF) as a marker of response to therapy in lung cancer. Indian J Cancer 2008; 45 (suppl): S22.
- Mohan A, Guleria R, Pathak AK, Kumar S, Pandey RM, Mohan C. Impact of symptoms, respiratory status, nutritional profile, and quality of life on response to chemotherapy in patients with advanced non small cell lung cancer. Chest 2007: 132 (4); S589A.
Awards / Honors
- Second Prize for Oral Paper Presentation (Differential expression of miR-197-3p and miR-375-3p and their correlation with survival outcomes and response to therapy in lung cancer) in NALCCON 2021: 12th Annual Conference of Indian Society for Study of Lung Cancer (ISSLC) organized on the virtual platform by JIPMER, Puducherry on 26-27 Nov. and 3-4 Dec. 2021.
- First Prize for Oral Paper Presentation (Analysis of the expression of PD-L1 and PD-L1 regulatory microRNAs in lung cancer) in NALCCON 2020: 10th Annual Conference of Indian Society for Study of Lung Cancer (ISSLC) organized on the virtual platform by Max Institute of Cancer Care, Delhi/NCR on 26-27 Sept. and 3-4 Oct. 2020.
- Young Investigator Award for the best oral paper presentation (Evaluation of deregulated circulating microRNA expression in advanced stage NSCLC patients) in NALCCON 2019: 9th Annual Conference of Indian Society for Study of Lung Cancer (ISSLC) organized at KGMU, Lucknow on 14-15 Dec. 2019.
- First Prize for Oral Paper Presentation (Evaluation of the expression and regulation of programmed death ligand-1 (PD-L1) in lung cancer) in NALCCON 2018: 8th Annual Conference of Indian Society for Study of Lung Cancer (ISSLC) organized at AIIMS Patna on 6-7th October, 2018.
- Second Prize for the Poster Presentation in International Symposium on "Frontiers in Cancer Research: Prevention to Therapeutics" held during November 15-16, 2013 at Amity University Uttar Pradesh.
- Elected Finance Secretary of Society of Young Scientists (SYS), AIIMS (2009-10).
- Third Prize in the International Competition on Article Writing: 2009 (Proteomics) organized by Institute of Integrative Omics and Applied Biotechnology, Nonakuri, Purba Medinipur, West Bengal, India.
- The Best Poster Award in RGCON 2009: 8th International Conference on Lung and Esophageal Cancers held at Rajiv Gandhi Cancer Institute & Research Centre, Delhi.
- Special Appreciation Award in IACR (Indian Association for Cancer Research) essay competition 2009 on “Bioinformatics in Cancer Drug Design”.
- Citation Award in IACR (Indian Association for Cancer Research) essay competition 2007 for the best essay on “Cancer Stem Cells”.
- Qualified Junior Research Fellowship (JRF-NET) in life science, conducted by Council of Scientific and Industrial Research (CSIR) in June 2004.
- Qualified Junior Research Fellowship (JRF-NET) in life science, conducted by Council of Scientific and Industrial Research (CSIR) in December 2003.
- Qualified ICMR JRF examination conducted on July 11, 2004 as Junior Research Fellow in ICMR Funded Research Projects/Scheme.
- Merit certificate for standing second in the college in the university examination in B.Sc-3rd year from Vaish P.G. College, Bhiwani in April 2002.
- Merit certificate for standing first in the college in the university examination in B.Sc-2nd year from Vaish P.G. College, Bhiwani in April 2001.
- Distinction in matriculation examination conducted by Board of School Education Haryana in 1997.
Membership
- Life Member of the Indian Society for Study of Lung Cancer (ISSLC)
- Life Member of the Indian Association for Cancer Research (IACR)
- Member of the Research and Education Society of Medical Oncology, AIIMS, New Delhi
- Associate Member of the Cancer Epigenetics Society
Teaching Experience
Four and half years of teaching experience in subjects like Animal Biotechnology, Cancer Biology, Molecular
Cell Biology, Recombinant DNA Technology and Gene Therapy (at UG/PG/PhD level)
Editorial Board Member
- Associate Editor (Cancer Section) of BMC Pulmonary Medicine (Springer Nature)
Journals / Grant Reviewer (Ad-hoc):
3 Biotech
American J. of Clinical Oncology
Annals of Medicine
Bioengineered
Biomarkers in Medicine
BMC Cancer
BMC Pulmonary Medicine
Cancer Biomarkers
Cancer Biotherapy & Radiopharmaceuticals
Cancer Investigation
Cancer Management & Research
Carcinogenesis
Cell Biology International
Cell Cycle
Cellular Signaling
Computational Biology & Chemistry
Current Problems in Cancer
Endocrine Connections
Epigenomics
European Journal of Cancer Care
FEBS Open Bio
Frontiers in Oncology Nutrition and Cancer
Experimental Cell Research
Future Oncology
Gene
Genetic Testing & Molecular Biomarkers
Human Cell
Indian Journal of Cancer
Journal of Biochemical & Molecular Toxicology
Journal of Oncology
Laboratory Investigation
Lung Cancer: Targets & Therapy
Medical Science Monitor
Molecular Diagnosis & Therapy
Molecular Oncology
OncoTargets and Therapy
Oxidative Medicine & Cellular Longevity
Pathology-Research & Practice
Personalized Medicine
Scientific Reports
Sultan Qaboos University Medical Journal
Technology in Cancer Research & Treatment
Tissue & Cell
Translational Medicine Communications
Seminars in Cancer Biology Cancer Communications
- Reviewed extramural research proposals submitted to SERB-DST for funding
- Reviewed ICMR fellowship reports
Oral Talks / Invited Lectures / Guest Lectures
- Invited lecture on “Clinical relevance of the expression of programmed death-ligand 1 (PD-L1) and regulatory microRNAs in lung cancer” at the 41st Annual Conference of IACR 2022 on “Combating Cancer: Biology to Therapy to Drug Resistance” and an International Symposium on “Cancer & Stem Cells" organized by Amity University Uttar Pradesh, Noida from 2-5 March, 2022.
- Guest lecture on “Molecular targeted therapy for cancer” delivered (virtually) to M.Sc.-Biotechnology students of Amity Institute of Biotechnology, Amity University Uttar Pradesh (Noida) on 12th June 2021.
- Invited lecture on “Prognostic significance of dysregulated microRNA expression in pediatric cytogenetically normal acute myeloid leukemia” at IACR 2019: Integrating Cancer Research into Comprehensive Disease Management: Recent Breakthroughs organized by PGIMER, Chandigarh from 1-3 March, 2019.
- Expert talk on “Detection of epigenetic alterations in circulating DNA/RNA as biomarkers in lung cancer” at World Cancer Congress held at Science City, Kolkata, WB, India from 20-22 Sept, 2017.
Posters Presented in Conference/Symposium
- Kumar S, Sharawat SK, Ali A, Malik PS, Mohan A, Guleria R. Diagnostic and prognostic utility of differentially expressed circulating microRNAs in Indian NSCLC patients (EP1.03-20). E-poster presented in IASLC 2019 World Conference on Lung Cancer held at Barcelona, Spain from 7-10 Sept, 2019.
- Gaur V, Bakhshi S, Sharma P, Kumar S. Dysregulated microRNA expression in the bone marrow of pediatric cytogenetically normal acute myeloid leukemia patients. Poster presented in 38th IACR Convention 2019 organized at PGIMER and Hotel Mountview, Chandigarh from 1-3 March, 2019.
- Gaur V, Bakhshi S, Sharma P, Kumar S. Small RNA sequencing reveals deregulated microRNA expression in the bone marrow of pediatric cytogenetically normal acute myeloid leukemia patients. Poster presented in 37th IACR Convention 2018 organized at Bose Institute, Salt Lake, Kolkata from Feb 23-25, 2018.
- Kumar S, Fisher PB. Using a cancer terminator virus (Ad.5/3-CTV) to improve the efficiency of hepatocellular cancer gene therapy. International Symposium on "Frontiers in Cancer Research: Prevention to Therapeutics" held during November 15-16, 2013 at Amity University Uttar Pradesh.
- Kumar S, Guleria R, Mohan A, Bharti AC, Das BC. Plasmanucleosome levels may predict therapeutic efficacy in patients with advanced non-small cell lung cancer. 3rd International Symposium on Translational Cancer Research. Bhubaneswar, Orissa, India, December 2009.
- Kumar S, Guleria R, Singh VK, Chandra S, Bharti AC, Das BC. Vascular endothelial growth factor (VEGF) in correlation with various clinico-pathological parameters in lung cancer. RGCON 2009: 8th International Conference on Lung and Esophageal Cancers. Rajiv Gandhi Cancer Institute & Research Centre, Delhi, March 2009.
- Kumar S, Das BC, Bharti AC, Mohan A, Guleria R, Kumar R. Vascular endothelial growth factor (VEGF) as a marker of response to therapy in lung cancer. 3rd Asia Pacific Lung Cancer Conference (APLCC), Hyderabad, India (2008).
Symposium Organized
- Organized (as a Finance Secretary) one-day national symposium on “Translational Research in Health Sciences” at AIIMS, NewDelhi, India on 24th November 2009.
Current Team Member(s)
- Harshul Kapoor: PhD student & JRF in the DBT-funded project (Date of registration: 12th April 2022) - M.Sc. Biotechnology (2021) from School of Biotechnology, JNU, New Delhi, India.
- Abhirup Mukhopadhyay: PhD student & DBT-JRF (Date of registration: 15th Oct. 2020) - M.Sc. (2019) from North-Eastern Hill University, Shillong, Meghalaya, India.
- Ms. Vijaylaxmi Saxena (working as a Project Associate 1 in the SERB-funded project from 1st Sept. 2022 till date) - Integrated Master's in Life Sciences in Biological and Life Science, Ahmedabad University (2019).
Lab Alumni
- Ishfaq Ahmad Mir (worked as a JRF in an ICMR-funded project from 1st May 2021 till 15th Aug. 2022) - M.Sc. Biotechnology (2019) from Jamia Milia Islamia, Delhi, India.
- Ms. Monu Pandey (worked as a JRF in an ICMR-funded project from 1st Oct. 2019 till 25th Feb. 2021) - Presently enrolled in the PhD program of IIT-Delhi, India.
- Dr. Vikas Gaur (worked as a JRF in a DBT-funded project from 6th Feb. 2015 till 5th Aug. 2018) - PhD from Amity Institute of Biotechnology, Amity University Uttar Pradesh in 2021. Current Position: Post-doctoral fellow at Cardinal Bernardin Cancer Center, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois, United States.
- Dr. Dhirendra K. Singh (worked as a JRF in a SERB-funded project from 1st Nov. 2014 till 18th Aug. 2015) - Earned his PhD degree from the Dept. of Microbiology, Univ. of Szeged, Hungary. Current Position: Post-doctoral fellow in Sweden.
Profile links
- Google Scholar: https://scholar.google.co.in/citations?user=MdG99mEAAAAJ&hl=en
- Webpage: https://sachinkumarlab.webs.com/
- ORCID: https://orcid.org/0000-0002-2594-6770
- My NCBI https://www.ncbi.nlm.nih.gov/myncbi/sachin.kumar.5/bibliography/public/
- Twitter: https://twitter.com/sachin_singla (ID: @sachin_singla)
- LinkedIn: https://www.linkedin.com/in/sachin-kumar-phd-72a11880/