Dr. Rizwana Quraishi

2. Name: Dr. Rizwana Quraishi

3. Designation: Additional Professor (Clinical Chemistry), Faculty In-charge, Laboratory Services, National Drug dependence Treatment Center, Department of Psychiatry, AIIMS, New Delhi.

4. Qualifications: M.Sc. (Biochemistry), Ph.D. (Clinical Chemistry)

5. Email ID: This email address is being protected from spambots. You need JavaScript enabled to view it.

6. Field of Interest: 

• Standardization of techniques for health damage assessment (treatment compliance and effectiveness studies).

• Genetic basis of addictive behaviours.

• Testing of Drugs of abuse (DOA) and therapeutic drug monitoring (TDM)

• Translational Research: Field applicable and patient friendly assessment techniques like dried blood assays.

7. Total number of publications till date: 40

8. Details of publications since 2010 onwards (the full citation)-

• Journal  articles (peer reviewed publications)

1. QuraishiR, Sarkar S, Parmar A, JainR, Das BK, AmbekarA. Exploring the clinical variables among drug dependent HIV-Positive: Implications for treatment strategies. Indian J Public Health 2022, 66(3), 331-333.

2. QuraishiR,VarshneyM,RaoA, Ambekar A. Evaluation of alcohol use pattern among OST patents using alcohol biomarkers. Indian J Psychiatry 2022, 64(3), 312-315.

3. Quraishi R, Kathiresan P, Verma K, Rao R, Jain R. Effect of chronic opioid use on the haematological and inflammatory markers: A retrospective study from North India. Indian J Psychiatry 2022;64:252-6.

4. QuraishiR, Sharma J, JainR,AmbekarA. Influence of COMT gene polymorphism on alcohol and tobacco consumption in North Indian treatment seeking population. Indian J Psychiatry 2021, 63(3), 240-244-315.

5. Quraishi R, Sarkar S, Jain R.Impact of chronic alcohol and opioid dependence on biochemical parameters: A retrospective case control study from a tertiary care treatment centre in North India. Addict Health 2021;13(3):148-55.

6. QuraishiR,VarshneyM,SinghA,SinghD,KumarM,RaoAetal.Useoffilterpapertomeasurealcoholbiomarkersamongopioiddependent patients on agonist maintenance treatment: A community based study. Indian J Psychol Med 2019, 41(6), 529-34.

7. Jain R, Quraishi R, Verma A, Ambekar A. Development and clinical evaluation of a dried urine spot method for detection of morphine among opioid users. Ind J Pharmacol. 2019, 51(1): 40-44.

8. Jain R, Quraishi R, Verma A. Evaluation of dried urine spot method to screen cotinine among tobacco dependents: An exploratory study. Ind J Psychol Med, 2017, 39(4), 2017: 469-474.

9. Jain R, Quraishi R, Ambekar A, Verma A, Gupta P. Dried urine spots for detection of benzodiazepines.Indian J Pharmacol, 2017, 4(5):1420-1423.

10. Quraishi R, Jain R, Mishra AK & Ambekar A. Association of ANKK I polymorphism with co-morbid alcohol and nicotine dependence: A pilot study from a tertiary care treatment center in North India”. Ind J Med Res 145, January 2017, pp 33-38

11. Quraishi R, Jain R, Ambekar A. Hematological Profile of Alcohol Dependent subjects: Report from a Tertiary Care Treatment Centre in India. Int J Pharma Res Health Sci. 2016; 4 (5): 1420-1423

12. Quraishi R, Lakshmy R, Mukhopadhyay AK, and Jailkhani BL. Transaminase Extraction and Stability from Dried Serum Samples. Schol J Appli Med Sci, 2014; 2 (1B): 169-170.

13. Quraishi R & Jain R. ANKKI/Taq A1 Genotyping from dried blood stored on filter paper among alcohol & nicotine dependantsubjects. British Biomed Bulletin 2014, 2 (1): 263-266.

14. Quraishi R, Jain R, Balhara YPS. Profile of Nicotine Use among Alcohol Dependent Patients Visiting a Tertiary Care Center in North India. Indian J Psychol Med. 2014; 36(2):174-8.

15. Quraishi R, Pattanayak RD, Jain R, Dhawan A. A Descriptive Study of Clinical, Hematological and Biochemical Parameters of Inhalant Users Seeking Treatment at a Tertiary Care Centre In India. Ind J of Psycho Med, 2013; 35(2): 174-179.

16. Chatterjee B, Quraishi R, Jain R.Socio-demographic and drug use characteristics of treatment-seeking cannabis users at a tertiary care centre in India. Add Dis and Their Treat, 2013; 33: 1-3.

17. Quraishi R, Jain R, Chatterjee B, Verma A. Laboratory profile of cannabis dependent treatment-seeking population at a tertiary care centre in India. Int J High Risk Behav Addict. 2013;2(3): 107-11.

18. Quraishi R, Jain R, Anish PK. Naltrexone level and biochemical profile of opiate dependent patients on Naltrexone Maintenance Programme: A pilot study. Add Dis and Their Treat Published ahead of print. 10.1097/ADT.0b013e31827a1ede

19. Quraishi R, Jain R, Ambekar A. The use of dried blood spot samples in screening drugs of abuse. Pharmacology & Pharmacy, 2013, 4, 152-159

20. Quraishi R, Lakshmy R, Mukhopadhyay AK, and Jailkhani BL.Analysis of the stability of urea in dried blood spots collected and stored on filter paper. Annals of Lab Med, 2013; 33: 1-3.

21. Quraishi R, Lakshmy R, Mukhopadhyay AK, and Jailkhani BL. Creatinine measurement and stability in dried Serum.J Diabetes Sci and Tech, 2012 Jul 1; 6 (4): 988-9

22. R Quraishi, R Lakshmy, k Luthara, AK Mukhopadhyay, BL Jailkhani. Apo E Genotyping from blood stored on filter paper. IJMR 2012; 135 (3): 318-321

23. Jain R, Quraishi R, Majumder P, and Pattanayak RD. Comparison of self-report and biological measures for alcohol, tobacco and illicit drug use in consecutive alcohol dependent patients visiting a tertiary care centre. Journal of Substance Use 1-9, Posted online on 19 April 2012.

24. Quraishi R, Jain R, Pattanayak RD. Laboratory Profile of current Injecting Drug Users seeking treatment at a tertiary care centre in India: What do the regular blood tests and HIV screening say?. Add dis and their treat, Early online ahead of publication, December 2011 doi: 10.1097/ADT.0b013e31824040432.

• Books/monographs/project reports/ proceedings from workshops (non-peer reviewed publications)

1. Mishra R, Deep R, Quraishi R, Jain R. Assessment for mitochondrial DNA A10398G polymorphism in Indian patients with bipolar I disorder. Bipolar Disorders (Journal) 2022; 24(S1): pp42 

2. Quraishi R, Jain R, Ambekar A. Use of filter paper in substance abuse treatment setting. Indian J Clin Biochem. 2019, 34 (1): 200.

3. QuraishiR,SinghD,AmbekarA,JainR,RaoR.Gammagutamyltransferasemeasurementindriedserumspots.AlcoholClinical& Experimental Research, 2018; 42 (S2), P1-1-48: 24A.

4. Ambekar A, Singh A, Quraishi R. Substance use disorders Shah N, De Sousa A (eds). A Short Textbook of Psychiatry. Bhalani Book Publishers, Mumbai. First Edition, 2018: pp 221-242. ISBN: 978-93-5311-908-9.

5. Quraishi R, Singh D, Ambekar A, Jain R, Rao R. Gamma gutamyl transferase measurement in dried serum spots. Alcohol Clinical & Experimental Research, 2018; 42 (S2), P1-1-48: 24A.

6. Chatterjee B, Quraishi R, Rao R. Genetic aspects of addictive disorders. Indian J Psychiatry 2018, 60 (supplement 1): S26

7. Quraishi R and Ambekar A. Genetics of alcohol use disorder. In: Dihingia S & Bhuyan D (Ed). Psychiatry Update. Indian Psychiatry Society, Dibrugarh and Psychiatrists of Dibrugarh, Assam. First Edition, 2018: pp 221-242. ISBN: 978-93-5311-908-9

8. Quraishi R, Jain R, Ambekar A. Use of filter paper in substance abuse treatment setting. Indian J Clin Biochem. 2019, 34 (1): 200.

9. Quraishi R, Jain R, Ambekar A. “Dried Blood Spots for Testing Drugs of Abuse” chapter in the book “Analytical testing for substance abuse” Published by The Royal Society of Chemistry, Cambridge, UK, 2017.
   

9. Presentations made at scientific meetings/ conferences/ workshops

1. Quraishi R, Kumar R, Sarkar S, Rao R, Ambekar A.Clinical and biochemical profile of alcohol dependent patients initiated on naltrexone. World Psychiatric Association 3-6 Aug 2022, Bangkok, Thailand.

2. Jain R, Chadda R, Lal R, Rao R, Quraishi R. High-throughput LC-QTOF Mass Method for the detection of designer piperazines in urine of substance users attending the tertiary care treatment center of North India. NIDA International  Forum, Minneapolis June 2022.

3. Mishra R, Deep R, Quraishi R, Jain R. Assessment for mitochondrial DNA A10398G polymorphism in Indian patients with bipolar I disorder. International society for Bipolar Disorders May 2022.

4. Quraishi R, Jain R. Complete blood count of alcohol dependent patients. 4 Dec 2020, Asian Internal Society of Addiction Medicine ( virtual mode)

5. Shukla T, Shani S, Kathiresan P, Quraishi R, Rao R, Jain R, Ambekar R. An observational prospective study assessing factors affecting abstinence with disulfiram treatment in patients with alcohol dependence” on July 2020 at 2^nd International conference of Research and Education Center for mental Health and Psychiatry, Taiwan (virtual mode).

6. Quraishi R, Sarkar S, Sharma A. Genetic underpinning of addiction. Symposium presented at International Society of Addiction Medicine (ISAM 2019),13-16 Nov 2019 in Delhi, India.

7. Quraishi R, Jain R, Ambekar A. Use of filter paper in substance abuse treatment setting. Poster presented at the Asian Pacific Federation of Clinical Biochemistry and Laboratory Medicine (APFCB 2019), 17-20 Nov 2019 in Jaipur, India.

8. Quraishi R, Chatterjee B and Rao R. Genetics of alcohol and opioid dependence: prevalence, association and implications in treatment outcome. Symposium presented at 3^rd Global conference of Biological Psychiatry, 23-26 Aug 2018 in Grand Hyatt, Mumbai.

9. Quraishi R, Singh D, Ambekar A, Jain R, Rao R. Gamma gutamyl transferase measurement in dried serum spots. Poster presented at the 19^th congress of international society for biomedical research on alcoholism (ISBRA2018), 9-13 Sept 2018 in Kyoto, Japan.

10. Chatterjee B, Quraishi R, Rao R. Genetic aspects of addictive disorders. Symposium accepted at Annual National Conference of Indian Psychiatric Society 5-8 Feb 2018 Ranchi, Jharkhand.

11. Quraishi R. Genetic predictors and moderators of treatment research in substance use (alcohol use disorders). Symposium presented at National Conference on Addiction Psychiatry dated 29^th Nov 2017.

12. Quraishi R, Jain R, Ambekar A, Verma A, Gupta P. Feasibility of using filter paper as a matrix for drug screening in urine of substance users. Presented at 49^th Annual Conference of Indian Pharmacological Society” 21-23 Oct 2016.

13. Quraishi R, Jain R, Bera SC, Ambekar A. Association of alcohol use pattern with liver enzyme levels: report from a tertiary care treatment centre in India. Presented at World association of Social Psychiatry, 2016.

14. Jain R, Quraishi R, Verma A, Ambekar A. “Evaluation of Dried urine spot method for detection of BZD among substance users”. International Association of Medico Legal Experts (IAMLE), Jan 2016.

15. Jain R, Quraishi R, Verma A. “Evaluation of Dried urine spot method for detection of cotinine among Tobacco users”. National Institute on Drug Abuse (NIDA) International Forum, June 2015.

16. Quraishi R, Jain R, Balhara YPS. “Profile of nicotine use among alcohol dependent patients visiting a tertiary care treatment centre in North India” Presented at 11^thIndo Pacific Association of Law, Medicine & Science Congress 2013 (Inpalms 2013) 7^th-10^th October 2013 Kuala Lumpur, Malaysia

17. Jain R, Quraishi R, Verma A, Ambekar A. An Efficient Method for Detection of Opiate in Dried Urine Specimens among Opioid Users.11^thIndo Pacific Association of Law, Medicine & Science Congress 2013 (Inpalms 2013) 7^th-10^th October 2013 Kuala Lumpur, Malaysia

18. Quraishi R and Jain R. ANKKI /Taq A Genotyping from blood stored on filter paper. 40^th National Conference of Association of Clinical Biochemists of India 3^rd-6^th Dec, 2013, NASC, PUSA (N Delhi)

19. Quraishi R, Jain R, Pattanayak RD, Dhawan A. Biochemical and Haematological Profile of Inhalant users seeking treatment at a tertiary care centre in India. 65^th Annual National Conference of Indian Psychiatric Society. January 10-13, 2013, Bangalore, Karnataka, India

20. Balhara YPS, Jain R, Quraishi R.A comparative urinalysis based study of cannabis use among opioid dependent individuals on Opioid Substitution Therapy (OST) with buprenorphine or buprenorphine-naloxone combination”. 65^th Annual National Conference of Indian Psychiatric Society. January 10-13, 2013, Bangalore, Karnataka, India.

21. Quraishi R, Jain R, Pattanayak RD, Dhawan A. Profile of Inhalant users seeking treatment at a tertiary care centre in India. 39^th Annual National Conference of Indian Associate of Clinical Psychologists. February 18-20, 2013, AIIMS (N Delhi)

22. QuraishiR, Raka Jain, R.D. Pattanayak Effect of age on the biochemical parameters of alcohol dependent patients visiting a tertiary care treatment centre in India: A pilot study. 3^rd International conference on legal medicine, medical negligence and litigation in medical practice and 3^rd international conference in current trends in forensic sciences and forensic medicine and toxicology. IMALE- 2012 (3^rd - 5^th February, 2012)

23. Jain R, Quraishi R, Majumder P, and Pattanayak RD. Comparison of self-report and biological measures for alcohol, tobacco and illicit drug use in consecutive alcohol dependent patients visiting a tertiary care centre. IMALE- 2012 (3^rd - 5^th February, 2012)

24. Quraishi R and Jain R. Morphine recovery from dried urine specimens” 10^th Indo-Pacific Congress on Legal Medicine and Forensic Science. Inpalms 2010 (25^th - 30^th October, 2010)

10. Investigator/ Co-investigator in funded projects along with year completed/ongoing

1. Evaluation of Neurocognitive, Personality, Emotional, and Social Biomarkers as Candidate Endophenotypes for Opioid Use Disorder & their Relationship with Polymorphism in Opioid & Dopamine Receptor Genes: Implications for Prevention & Treatment. Co-PI (ICMR funded, 2021 ongoing)

2. Metabolic and addiction indices in Indian opioid dependent subjects on Buprenorphine-naloxone Maintenance treatment: A longitudinal study. Co-PI(ICMR funded, 2022-25)

3. Development and pilot testing of a biomarker feedback cognitive social health information programme during pregnancy. Co-PI(ICMR funded, 2022 ongoing)

4. A Cross-Sectional Study to Screen for Psycho-sexual Health Disorders and Measure Neurochemical Correlates in Gynaecology Cancer Survivors. Co- PI (AIIMS funded, 2021 ongoing).

5. HIV, Hepatitis B and C testing in individuals receiving agonist treatment for injecting drug use at a community clinic in Delhi: a cross sectional assessment of risk factors and seroprevalence”. Co-PI(AIIMS funded, 2021 ongoing)

6. An evaluation of mu opioid receptor gene polymorphism (A118G) and long term naltrexone treatment response in North-Indian alcohol dependent patients. Principal Investigator. ICMR funded study (2019-ongoing).

7. Assessment of clinical profile, mitochondrial DNA 10398, peripheral glucose utilization (HOMA-IR) and inflammation (TNF-a) in Matrilineal Bipolar Disorder. Co-PI(Intramural project, 2019 ongoing).

8. A functional polymorphism of dopamine beta hydroxylase gene and disulfiram treatment response in patients with alcohol dependence: A pilot exploratory study. Principal Investigator. (AIIMS funded Study (2018-20).

9. Biomarkers of Lithium response in Bipolar disorder: assessment of the clinical markers, peripheral blood based markers and structural neuroimaging markers (pertaining to gray matter volume) in individuals with bipolar disorder on long-term lithium prophylaxis. Co-Investigator. (2017 Ongoing).

10. Detection of New Psychoactive Substances among Substance Abuse Treatment Seekers in India: A Multi-centric Study. Co-Investigator. (Funded by Ministry of Revenue, GOI, 2017-22).

11. Feasibility of transporting blood/serum samples onto filter paper to screen for biomarkers of harmful alcohol use among opioid dependent patients on agonist maintenance treatment: A pilot study in community setting. (PI) (AIIMS funding) (2016-18).

12. Feasibility of transporting urine samples of drug users on filter paper for screening drugs of abuse: A pilot exploratory study. Co-PI (ICMR funded, 2012-15).
    

11. Investigator/Co-investigator in non-funded projects along with year and title completed/ongoing

1. A functional polymorphism of aldehyde dehydrogenase gene (rs671) and disulfiram treatment response in patients with alcohol dependence: A pilot exploratory study. PI (2020 ongoing).

2. Clinical laboratory profile of opioid dependent patients: A retrospective chart review study. (PI) (2019-20)

3. To explore and compare the association of various demographic, clinical and laboratory factors with Delirium Tremens (DT) among patients with Alcohol Dependence (AD), admitted with and without a diagnosis of DT, based upon review of clinical records. Departmental study. (2017-20) Principal Investigator.

4. A cross sectional study to measure the frequency of the BDNF Met66 allele in patients seeking treatment for alcohol use disorder. (MD Thesis, as co-supervisor, 2020).

5. A randomized double blind sham controlled trial for evaluating effectiveness and tolerability of high definition transcranial direct current stimulation in depression. (MD Thesis, as co-supervisor, 2020).
   

12. Thesis supervised for MD/ DM/PhD

- as guide (number only): 2 MD  

-as co-guide (number only): 2 DM, 5 MD, 2 Ph.D. (Member)

13. Awards and Honours:

1. Young psychiatrist award at 2nd International conference of Research and Education Center for mental Health and Psychiatry, Taiwan, July 2020. (2^nd Author, Findings from research study as PI).

2. On invitation authored a book chapter for The Royal Society of Chemistry, Cambridge, UK. 2017

3. Chaired sessions on Mental Health at World Congress of Social Psychiatry, 2016 and National Conference on Addiction Medicine, 2017.

4. Awarded travel grant from ICMR to attend; 11^thIndo Pacific Association of Law, Medicine & Science Congress 2013, Kuala Lumpur, Malaysia

5. Awarded travel grant from DST to attend American Association Clinical Chemistry, Annual meeting, USA 2005.

14. Any other relevant information

1. Managing the laboratory services to assess health damage in patients with substance use. It includes Chemistry, Hematology and Electrolyte measurements.

2. Looking after the drugs of abuse testing laboratory and therapeutic drug monitoring.

3. The NDDTC Laboratory has the state of art instruments to test New Psychoactive substance.

4. The genetics laboratory at NDDTC is involved in research pertaining treatment response to the therapeutic interventions and the genetic vulnerability towards drugs use and abuse.

5. Running ‘External Quality Control Programme’ for all investigations at NDDTC, Monthly reporting of blinded external sample for the Chemistry, Hematology & electrolytes parameters.

6. Working as Reviewer

• Indian Journal of Psychiatry.

• Indian Journal of Medical Research.

• Journal of Substance Abuse & Treatment.

• Journal of Substance Abuse.

• Journal of Pharmacology and Pharmacy.

• Indian Journal of Clinical Biochemistry.