Aruna Nambirajan

Full Name

Dr. Aruna Nambirajan

Qualifications

MD (Pathology), DNB

Office Address

3001, Third Floor, Convergence Block, AIIMS, New Delhi, 110029

Specialty

Thoracic Pathology, Cytopathology

Areas of academic and research interest

Lung cancer, Molecular diagnostics, Pulmonary cytology, Undergraduate teaching

Notable Awards and Honors

• Dr. N C Nayak Talented Young Pathologist Award, Delhi chapter IAPM, 2022

• AIIMS Oncology Research Award, Clinical Sciences, 3^rd prize, 2021 – co-author in winning publication

• AIIMS Oncology Research Award, Clinical Sciences, 2^nd place, 2020 – co-author in winning publication

• Developing Nations Award – Winning Finalist, World Conference on Lung Cancer, Worldwide Virtual Event, 2021

• AIIMS Oncology Award (Basic Research Category) 1^st place, 2020 – first author in winning publication

• AIIMS Oncology Award (Basic Research Category) 2^nd place, 2019 – co-author in winning publication

• Young Investigator Travel award, International Congress of Neuropathology, Japan, 2018

• Certificate of Excellence (Basic research Category), AIIMS foundation day, 2018- first author in winning publication

• Colonel DB Nayar Memorial Award for best paper in the field of molecular cytopathology, AC of IAC, Shillong, 2017

• ISNO (Indian Society of Neuro-oncology) President’s Annual award for best student in Clinical Neuro-Oncology, ISNOCON, Hyderabad, 2016

• Dr V R Khanolkar Award for best published work, APCON, 2014

• DNB Pathology (All India Topper, NBE President’s Gold Medal), 2014

• MD Pathology (Best Outgoing Junior Resident, AIIMS, New Delhi, Dr V Ramalingaswamy Gold Medal), 2013

• MBBS (Best Outgoing MBBS student, Chengelpet Govt. Medical College, Tamilnadu), 2010

Books and chapters

• Nambirajan A., Jain D. (2021) Immunohistochemical Detection of p40 Expression in Lung Cancer Clinical Samples. In: Santiago-Cardona P.G. (eds) Lung Cancer. Methods in Molecular Biology, vol 2279. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1278-1_2

• Nambirajan A, Singh V, Jain D. Molecular pathology of thymic epithelial tumors. In: Atlas of Thymic Pathology; Eds: Jain D, Bishop JA, Wick MR. Springer 2020: pgs. 169-172

• Nambirajan A. (2020) Infectious diseases. In: Eds. Singh MK, Kumar V. Robbins and Cotran Pathologic Basis of Disease: Vol II, 10e - South Asia Edition, pgs. 1332-1333

• Nambirajan A., Sharma A., Sharma M.C. (2021) Pathology and Molecular Pathology of Ependymoma. In: Mallick S., Giridhar P., Rath G.K. (eds) Evidence based practice in Neuro-oncology. Springer, Singapore. https://doi.org/10.1007/978-981-16-2659-3_4

• Nambirajan A., Singh J., Suri V. (2021) Pathology and Molecular Pathology of Meningioma. In: Mallick S., Giridhar P., Rath G.K. (eds) Evidence based practice in Neuro-oncology. Springer, Singapore. https://doi.org/10.1007/978-981-16-2659-3_5

• Giridhar P., Nambirajan A., Benson R. (2021) Ependymoma. In: Mallick S., Giridhar P., Rath G.K. (eds) Evidence based practice in Neuro-oncology. Springer, Singapore. https://doi.org/10.1007/978-981-16-2659-3_24

• Suri V, Nambirajan A, Sharma MC, Sarkar C. Surgical Pathology of intractable epilepsy. In. Progress in clinical neurosciences, Volume 30; Eds: Muthukumar N and Goyal V, Thieme Delhi, 2016: pgs 13-32.

• Nambirajan A, Sharma MC. Ependymal tumors. In. Essentials of Diagnostic Surgical Neuropathology; Eds: Sarkar C, Santosh V, Chacko G. Thieme Delhi 2018: pgs 41-49.

Top Research publications

1. Nambirajan A, Rana D, Samant K, Prabakaran A, Malik P, Jain D. Multiplex fluorescence in situ hybridization testing for anaplastic lymphoma kinase and c-ros oncogene 1 gene rearrangements on cytology smears in lung adenocarcinomas: comparative study with formalin-fixed paraffin-embedded sections. J Am Soc Cytopathol. 2022 Jan 13:S2213-2945(22)00001-1.

2. Mahajan S, Nambirajan A, Gupta I, Gupta P, Gupta N, Jain D. Malignant pleural effusion cell blocks are reliable resources for PD-L1 analysis in advanced lung adenocarcinomas: a concordance study with matched histology samples. J Am Soc Cytopathol. 2022 Accepted April 14.

3. Jain D, Nambirajan A, Chen G, Geisinger K, Hiroshima K, Layfield L, Minami Y, Moreira AL, Motoi N, Papotti M, Rekhtman N, Russell PA, Prince SS, Schmitt F, Yatabe Y, Eppenberger-Castori S, Bubendorf L; IASLC Pathology Committee. Non-small cell lung carcinoma subtyping in conventional cytology: Results of the IASLC Cytology Working Group survey to determine specific cytomorphological criteria for adenocarcinoma and squamous cell carcinoma. J Thorac Oncol. 2022:S1556-0864(22)00145-9.

4. Gheware A, Ray A, Rana D, Bajpai P, Nambirajan A, Arulselvi S, Mathur P, Trikha A, Arava S, Das P, Mridha AR, Singh G, Soneja M, Nischal N, Lalwani S, Wig N, Sarkar C, Jain D. ACE2 protein expression in lung tissues of severe COVID-19 infection. Sci Rep. 2022 Mar 8;12(1):4058.

5. Ray A, Jain D, Goel A, Agarwal S, Swaroop S, Das P, Arava SK, Mridha AR, Nambirajan A, Singh G, Arulselvi S, Mathur P, Kumar S, Sahni S, Nehra J, Nazneen, Bm M, Rastogi N, Mahato S, Gupta C, Bharadhan S, Dhital G, Goel P, Pandey P, Kn S, Chaudhary S, Keri VC, Chauhan VS, Mahishi N, Shahi A, R R, Gupta BK, Aggarwal R, Soni KD, Nischal N, Soneja M, Lalwani S, Sarkar C, Guleria R, Wig N, Trikha A. Clinico-pathological features in fatal COVID-19 infection: a preliminary experience of a tertiary care center in North India using postmortem minimally invasive tissue sampling. Expert Rev Respir Med. 2021 Jul 24:1-9. doi: 10.1080/17476348.2021.1951708.

6. Satapathy S, Singh V, Nambirajan A, Malik PS, Tanwar P, Mehta A, Suryavanshi M, Thulkar S, Mohan A, Jain D. EGFR mutation testing on plasma and urine samples: A pilot study evaluating the value of liquid biopsy in lung cancer diagnosis and management. Curr Probl Cancer. 2021 Mar 3:100722. doi: 10.1016/j.currproblcancer.2021.100722. Epub ahead of print.

7. Nambirajan A, Singh V, Bhardwaj N, Mittal S, Kumar S, Jain D. SMARCA4/BRG1-deficient non-small cell lung carcinomas: a case series and review of the literature. Arch Pathol Lab Med. 2021;145:90-98.

8. Singh V, Nambirajan A, Malik PS, Kaur K, Mohan A, Jain D. EGFR mutation testing in cytology smears of advanced non-small cell lung carcinomas: practical applications in low resource laboratories. Cytopathology. 2021; 32:287-289.

9. Singh V, Nambirajan A, Malik PS, Thulkar S, Pandey RM, Luthra K, Arava S, Ray R, Mohan A, Jain D. Spectrum of uncommon and compound epidermal growth factor receptor mutations in non-small cell lung carcinomas with treatment response and outcome analysis: a study from India. Lung Cancer. 2020;149:53-60.

10. Nakra T, Nambirajan A, Guleria P, Phulware R, Jain D. Insulinoma-associated protein 1 is a robust nuclear immunostain for the diagnosis of small cell lung carcinoma in cytology smears. Cancer Cytopathol. 2019;127:539-548.

Ongoing Research Projects

• Molecular mechanisms of drug resistance in non-small cell lung carcinoma (AIIMS funded – ongoing)

• Corticotrope pituitary adenomas (ICMR funded – ongoing)

• Spinal ependymomas (AIIMS funded – ongoing)

Links

Publications:https://www.ncbi.nlm.nih.gov/pubmed/?term=Nambirajan+A%5Bauthor%5D

Citations: https://scholar.google.com/citations?user=JLJ-uBwAAAAJ&hl=en

ResearchGate:https://www.researchgate.net/profile/Aruna-Nambirajan