Patient Care

1. 14^th June 2018 – World Blood Donor Day Celebration

 COMMUNITY EDUCATION: It is a well-known fact that blood cannot be manufactured. It is a living tissue with limited shelf life and availability and it can only be obtained through one's blood donation. To maintain the supply of safe blood, recruiting and retaining of voluntary non-remunerated blood donors is essential. For this purpose, Blood centre, Main Hospital of AIIMS New Delhi was always at the forefront in organizing voluntary blood donation camps. Events like "Nukkad Nakat, Cyclothon, Walkathon, Marathon, Flash Mob' were also organized to promote and propagate the message of Voluntary Blood Donation.

Publications, Presentations, Regional and Global Collaborations, Research

Publications:

Journal articles:

1. Kumar R, Pandey HC, Jain R, Coshic P, Jain P. Retrospective comparison between non-treponemal and treponemal tests for screening of blood donors for syphilis and their correlation with donor history in a tertiary care teaching hospital. Transfus Apher Sci 2020; 10.1016/j.transci.2020.102814.
2. Kumar R, Jain R, Coshic P, Pandey HC. Utility of a combined approach using audit, education and information technology tools to improve transfusion practices. ISBT Science series 2020, doi:10.1111/voxs.12577
3. Pandey HC, Coshic P, CSC, Arcot PJ, Kumar K. Blood supply management in times of SARS‐CoV‐2 pandemic – challenges, strategies adopted, and the lessons learned from the experience of a hospital‐based blood centre. Vox Sang. 2020, doi.org/10.1111/vox.13019.
4. Senapati J, Aggarwal, Louise L, …Pandey HC et al. Transfusion practices during the COVID-19 pandemic: An experience from a hematology daycare in India. Transfus Apher Sci 2020. doi.org/10.1016/j.transci.2020.103025.
5. Pandey HC, Dhiman Y, Chippy CS, Coshic P, Jain P. Seroprevalence of SARS-Coronavirus 2 among asymptomatic healthy blood donors from healthcare and non-healthcare settings: Implications for safety of blood donors and blood collection staff during blood donation. Transfus Apher Sci 2021. https://doi.org/10.1016/j.transci.2021.103118 (accepted, pre-proof).
6. Dhiman Y, Coshic P, Pandey HC et al. Deterrents in recruitment of COVID-19 convalescent plasma donors: Experience from a hospital-based blood centre in India. Trans Med 2021. https://doi.org/10.1111/tme.12768 (accepted, in production).
7. Al Riyami AZ, Burnouf T, Yazer M, Triulzi D,….Pandey HC et al. International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Responses. Vox Sang. 2021 May 20. doi: 10.1111/vox.13114.
8. Al Riyami AZ, Burnouf T, Yazer M, Triulzi D,…. Pandey HC et al. International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Protocols, Challenges and Lessons Learned: Summary. Vox Sang. 2021 May 20. doi: 10.1111/vox.13113.
9. Jain R, Kumar R, Coshic P, Pandey HC, Jain S. Effectiveness of personal communication strategy in motivating replacement donors to become voluntary blood donors. ISBT Science Series 2021, 16 (2), 196-203.
10. Jain R, Kumar R, Pandey HC, Coshic P. Pre-Release Visual Inspection of Blood Components: A Stitch in Time Saves Nine. Indian J Hematol Blood Transfus (2021). https://doi.org/10.1007/s12288-021-01416-x
11. Arcot PJ, Pandey HC, Coshic P, Jain P, Kumar S, Chakroborty S. Comparative evaluation of ADVIA Centaur® XP chemiluminescence system for screening of HBV, HCV, HIV and syphilis in Indian blood donors. Transfus Apher Sci. 2021 Nov 12:103318. doi: 10.1016/j.transci.2021.103318

List of oral papers/posters presented

Abstracts

1. Chippy CS, Pandey HC, Seth T, Coshic P, Thapaliyal RM, Sharma V. High Dose IVIG & Steroid for Incompatible Transfusion in a Case with Multiple Alloantibody. Indian J Hematol Blood Transfus (2019) 35: S150
2. Vijayaran M, Aggarwal M, Gudala SP…Pandey HC et al. CMV Infection in An Infant Presenting as Steroid Refractory Aiha in 61st Annual Conference of Indian Society of Hematology & Blood Transfusion (ISHBT) November 2020. Indian J Hematol Blood Transfus 36, 81 (2020)
3. Pandey HC, Coshic C, Kumar R et al. Evaluation of radio frequency identification technology for inventory management and patient identification before transfusion. Vox Sanguinis (2020) 115 (Suppl. s1), 95
4. Pandey HC, Varghese M, Rana A et al. Estimation of incidence rates & residual risks of HIV, HBV and HCV in Indian settings using NAT window period yield cases. Vox Sanguinis (2020) 115 (Suppl. s1), 194
5. Chippy C, Pandey HC, Mahapatra M et al. Prospective observational study to find the prevalence & to serologically characterize autoimmune hemolytic anemia (AIHA) patients in a tertiary care teaching centre. Vox Sanguinis (2020) 115 (Suppl. s1), 248

        Book chapters:

1. Chaurasia R, Coshic P, Pandey HC, Patidar G. Transfusion medicine in Robbins & Cotran Pathologic Basis of Disease 10^th edition (Southeast Asia Edition). Editor: Manoj K Singh, Vinay Kumar. Elsevier India 2020, 1348-56.

Presentations:

Ongoing Research projects:

Departmental projects:

1. Prospective observational study to assess the prevalence of platelet refractoriness and its reasons in patients receiving multiple platelet transfusion in an Indian setting
2. Incidence of delayed adverse events in blood donors following whole blood donation in Indian setting
3. Retrospective analysis of differences in red blood cell usage across different gender, age groups and specialties in a tertiary care hospital
4. Characterization of initially reactive discordant results tested by chemiluminescence (CLIA)and nucleic acid testing (NAT)during blood donor screening for hepatitis-B and hepatitis-C
5. Incidence of adverse transfusion reactions and analysis of factors associated with these reactions: A four-year experience from a tertiary care hospital from India
6. 6.      Diagnostic accuracy of using cell free fetal DNA isolated from mother's plasma for determination of fetal Rh D status during antenatal period as compared to determination of D status using serological tests in cord blood (Funded intramurally 5 lac)

Collaborative research projects with other departments

1. H1-MR Spectroscopy based evaluation of metabolic abnormalities in anterior cingulate cortex, hippocampus and amygdala in treatment naïve patients with unipolar and bipolar depression and its relationship with peripheral glutaminase.
2. Analyzing the effect of novel Pyrazole-based small molecule inhibitor on endosomal TLR-induced signaling activation in healthy peripheral blood mononuclear cells
3. Analyzing the effect of novel Pyrazole-based small molecule inhibitor on cell surface TLR-induced signaling activation in healthy peripheral blood mononuclear cells
4. Evaluation of immunomodulatory activities of Toll-like receptor signaling inhibitors in lupus peripheral blood mononuclear cells
5. Evaluation of the potential impact of determination of paternal RhD zygosity and non-invasive fetal RhD genotyping using circulating cell-free fetal DNA from maternal plasma in the antenatal monitoring of alloimmunized pregnant women: A pilot study on cost-benefit analysis
6. Determination of reference ranges for healthy individuals for new red blood cell and reticulocyte parameters in Indian population