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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi
 

Departmental Projects  

1

Pattern of care and survival studies in breast, head &neck and cervical cancer.

2

Evaluation of Diffusion Weighted Magnetic Resonance Imaging for assessment of response to Neo Adjuvant Chemotherapy in advanced Squamous cell carcinoma of oral cavity

3

Role of Fibrin sealant in Ilio Inguinal Block Dissection to reduce the rate of lymphatic drainage and seroma formation, thereby morbidity

4

Role of Fibrin sealant in Ilio Inguinal Block Dissection to reduce the rate of lymphatic drainage and seroma formation, thereby morbidity

5

A randomized controlled trial comparing single dose versus three doses of antibiotic prophylaxis in surgical oncology patients with clean wounds.

6

Role  of  PET– CT  Scan ( Positron Emission Tomography and CT Scan ) in  the  Staging  of  Locally  Advanced / Recurrent Breast  Cancer as a Single modality in Comparison   to   Multiple   Organ  Directed  Conventional  Investigations (C.I) A prospective Study.

7

Low cost, low dose, oral, neoadjuvant chemotherapy protocol in locally advanced borderline oral cancers - Feasibility study.

8

Analysis of a computerized prospective database of patients with uncommon sites of oral cancer presenting to IRCH, AIIMS.

9

Analysis of a prospective computerized database of colon cancer patients presenting to IRCH-AIIMS.

10

Prospective analysis the role of Positron emission tomography in preoperative evaluation of resectable soft tissue sarcoma and correlation with histo-pathological grading

11

Analysis of a prospective computerized database of esophageal cancer patients presenting to IRCH-AIIMS.

12

Clinical profiles and patterns of palliative surgery in cancer patients: An ambispective Study.

13

Analysis of a prospective computerized database of Gastric cancer patients presenting to IRCH-AIIMS.

14

A prospective study of Assessment of Breast anthropometry in Indian breast cancer patients.

15

Peri operative morbidity after complete cytoreduction and HIPEC

16

River Flow’ Incision for decreasing morbidity of Ilio-Inguinal Dissection

17

Pre-operative short course radiotherapy Vs NACT- long term radiotherapy in the management of locally advanced rectal cancer

18

Analysis of a computerized prospective database of patients with early breast cancer.

19

A prospective study evaluating incidence of DVT in patients undergoing surgery for thoracic and abdomino-pelvic malignancies.

20

Review of clinic-pathological, epidemiological, imaging accuracy, treatment outcomes and prognostic factors of operable pulmonary metastases in Department of Surgical Oncology, IRCH, AIIMS.  

21

Role  of  PET– CT  Scan ( Positron Emission Tomography and CT Scan ) in  the  Staging  of  Locally  Advanced / Recurrent Breast  Cancer as a Single modality in Comparison   to   Multiple   Organ  Directed  Conventional  Investigations (C.I)

22

Retrospective Analysis of A prospective computerized data base of patients with Early Tongue cancer.

23

Analysis of a Prospective computerized clinical database of Soft Tissue Sarcomas

24

A Prospective Study evaluating role of Ultrasound and Ultrasound guided FNAC in the assessment of cervical node metastasis in Oral Cancer

25

Molecular profiling (BRAF and K-RAS gene mutation) in differentiated thyroid cancer (DTC) in Indian patients operated at BRA IRCH AIIMS .

26

A prospective and Retrospective study of complex Breast conservation therapy.  

27

A prospective study to validate the role of Integrated Positron Emission Tomography-Computed Tomography and Endobronchial Ultrasound and guided Transbronchial needle aspiration in the mediastinal staging of resectable Non small cell lung cancer

28

Standardizing Surgico-pathological evaluation of oral squamous cell carcinomas specimens - A prospective study  

29

A prospective study to validate the role of PET CT and EBUS in the staging of resectable Non Small Cell Lung Cancer”

30

Efficacy of Neoadjuvant chemotherapy in carcinoma esophagus- A pilot study comparing Cisplatin+5-FU with Paclitaxel + Carboplatin

31

A prospective randomized control trial comparing intracostal with pericostal throractomy closure to evaluate post thoracotmy pain syndromes

32

Complex breast conservation therapy for breast cancer patient selection criteria clinical profile and outcomes

33

Patterns of care and survival studies on cancer in childhood, lymphoid and hematopoietic malignancies, other gynecological malignancies

34

Immuno-phenotypic profile of tumor infiltrating cells of the immune system & expression of PDL1 in triple negative/Her-2 neu positive breast cancer patients and their correlation with response to neoadjuvant chemotherapy

35

Comparative Sphingolipid profiling of breast cancer cell and tissue types for identification of Potential Metastatic Biomarkers

36

Development of Standard Operating Procedures (SOP) of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in peritoneal surface malignancies for Government set up in India. 

37

Clinical significance of cell-free DNA in intraoperative pleural lavage fluid and plasma in patients with non-small cell lung cancer (NSCLC): A pilot study

38

Role of T-regulatory cells (Tregs) and their clinical correlation in epithelial ovarian cancer.  

39

Evaluation of peritoneal cancer index (PCI) in primary advanced ovarian epithelial carcinoma amongst Indian population.

40

A prospective observational study comparing CT scan vs PET CT scan in carcinoma ovary for determining the pre-operative disease burden and resectability  

41

Efficacy of Neoadjuvant chemotherapy protocol in locally advanced, carcinoma oral cavity- A randomized, pilot study comparing Cisplatin+5-FU with Paclitaxel + Carboplatin

42

A study of young colorectal cancer patients - Clinical profile, treatment and relapse patterns, learning basic laboratory techniques of molecular biology for miRNA extraction in colon cancer patients. 

43

Clinical Utility of cell-free DNA in intraoperative pleural lavage fluid and plasma for patients with resectable primary pulmonary malignancies – A pilot study

44

Awareness and Knowledge of Indian Breast Cancer patients pertaining to genetic aspect of Breast cancer

45

Prospective study to evaluate the accuracy of axillary staging using Ultrasound guided FNAC  in early breast cancer

46

Comparison of pulmonary metastasis detected with PET-CT vs NCCT chest with surgical pathology

 

47

Evaluation of Indocyanine green dye-based navigation surgery in optimizing axillary management of carcinoma breast.

48

Learning Basic Lab Techniques and Analysis of Colorectal cancer data base.  

49

Prevalence of sarcopenia in patients with upper gastrointestinal and lung malignancy undergoing surgical resection and its impact on immediate postoperative outcomes:

A prospective observational study

50

Patterns of Care and Survival Studies on Gall Bladder Cancer under ICMR- National Cancer Registry Programme (NCRP)

51

Validation of role of PET-CT and Diagnostic Laparoscopy in the gall bladder cancer patients – A prospective study.  

52

Feasibility study of dual technique- blue dye and fluorescence imaging for detection of sentinel node in oral cavity cancer – a prospective validation study

53

Prospective assessment of quality indicators of perioperative outcomes in major oncological surgeries at a high-volume tertiary care center

54

A prospective comparative study between HIPEC and EPIC and a Retrospective analytic survey of HIPEC patients.

55

SURAKHA – Breast Cancer Genetic awareness and risk Assessment

56

Predicting the response to neo-adjuvant chemotherapy by analysis of  exome and transcriptome in squamous cell carcinoma of esophagus

57

Breast and Ovarian cancer awareness

58

Role of heavy metals As etiology for carcinoma of the gallbladder

59

Hospital Based Cancer Registry at National Cancer Institute (NCI)-AIIMS

60

Functional recovery and Return to work after Thoracic surgery in patients with Malignant

thoracic Diseases: A Prospective study

61

A pilot study to assess role of preoperative chemoradiotherapy in locally advanced / recurrent extremity soft tissue sarcoma & audit of soft tissue sarcoma database.

62

Prospective study of in person versus online cancer genetic counseling and ambispective evaluation of patients undergoing risk reducing surgery.

63

A study to evaluate time trends of clinical profile and risk factors among breast cancer patients and learning basic laboratory techniques of breast cancer lipidomics

64

Prospective evaluation of diagnostic imaging methods and its impact on surgical decision-making algorithm in the management of nodal disease in recurrent differentiated thyroid cancer and audit of the thyroid cancer database for evaluation of clinical and surgical spectrum and outcomes

65

A study evaluating MIS for of colorectal cancer patients and learning basic laboratory techniques of molecular biology for miRNA extraction in colon and rectal cancer patients

66

Prospective study on the expression of cancer-testis antigen (CT45) in the patients of advanced epithelial ovarian cancer undergoing Hyperthermic Intraperitoneal Chemotherapy and its correlation with response to platinum-based chemotherapy

67

Pilot study to evaluate the role of Toluidine Blue Dye and Narrow Band Imaging for assessment of malignant and potentially malignant disorders in oral cavity and update and analysis of Oral Cancer Database

68

Clinical spectrum, patterns of care and outcomes of Indian cancer patients treated by Multidisciplinary team management

69

Understanding the impact of gut microbiome dysbiosis and metabolic alterations in the pathogenesis of early onset (EOCRC) Colorectal Cancer (CRC)

70

Evaluation of tumor derived exosomes in blood during pre and post treatment of pancreatic cancer patients

71

Role of Circulating Tumor DNA (ctDNA) As A Surrogate Marker in Ovarian Cancer - A Pilot Study

72

Assessment of cell free DNA (cfDNA) as a biomarker in common gastrointestinal track cancers

73

POCSS for PBCR -Head &Neck, Breast and Cervix cancers

74

Prospective evaluation of diagnostic imaging methods and its impact on surgical decision-making algorithm in the management of nodal disease in recurrent differentiated thyroid cancer and audit of the thyroid cancer database for evaluation of clinical and surgical spectrum and outcomes

 

Collaborative Projects

 

1

Diversity of Oral microbiome of smokeless tobacco induced oral cancer patients as compared to tobacco chewers and non tobacco chewer healthy individuals- A metagenomic approach”

2

Metallic tumor markers for breast cancer. Design, development and clinical implications.

3

Evaluation of circulating cell free DNA as a prognostic marker in breast cancer

4

A study of Promoter Methylation of PTEN in Sporadic BREAST Cancer from North India

5

Analyzing FGFR2 and candidate genes affecting Its Downstream Signaling In Breast Cancer

6

A comprehensive analysis of mammalian target of rapamycin (mTOR) and mitogen activated protein (MAP) Kinase signaling pathways in non- small cell lung carcinoma

7

Role of Multiparametric MRI in Evaluation of Locally Advanced Rectal Cancer.

8

Circulating microRNAs as biomarkers for testicular germ cell tumors: A pilot study

9

Randomized control trial of combined EBRT plus HD brachy therapy boost versus EBRT alone with IMRT in intermediate & high risk prostate cancer.

10

Functional status and co morbidities of older patients with cancer

11

Molecular analysis of LIFR and YAP genes in Indian Breast Cancer patients

12

Molecular Analysis of lats2 and Fosp³ genes in Indian Breast Cancer patients

13

Expression studies of FOXO gene family in Indian Breast Cancer Patients

14

A study to assess the effectiveness of an educational package on knowledge regarding post-operative care of oral cancer patient’s relatives following discharge.

15

A study to assess the level of fatigue and presence of functional deficit in adult patients undergoing upfront surgery for solid tumors in pre and post-surgical phase in AIIMS

16

Differentiating inflammatory and metastatic mediastinal lymphadenopathy on 18-FDG- PET/CT in lung cancer: Role of steroid suppression

17

Etiology of oral cancer in Indian population younger than 30 years

18

Evaluation of HE4 level in epithelial ovarian cancer for diagnosis & monitoring of therapy

19

An economic analysis of alternative treatment methods of ovarian cancer in India: An appraisal of economic burden, quality of life and mortality risk.

20

Evaluation of Human Epididymis Protein 4 (HE4) level in the diagnosis of ovarian cancer

21

Bio-statistical Models for Evaluation of Lymph Node involvement among oral cancer patients

22

Role of Real Time Ultrasonography fused with PET-CT for image guidance and intervention: A nodal approach in management of Thyroid cancer”

23

Evaluation of the effect of Prosthodontic Rehabilitation on quality of Life and Psychological distress in Maxillectomy patients – A preliminary study

24

To evaluate whether a predictive microRNA signature from TCGA acts as a biomarker in Indian colorectal cancer (CRC) patients”

25

Dosimetric study in children and young adults with differentiated Thyroid cancer undergoing radioiodine (¹³¹I-Na) therapy”

26

Isolation Identification and characterization of cancer stem cells from different histopathological grades of colorectal carcinoma”

27

Association of HIPEC treatment with expression of T regulatory cells (FOXP3) in epithelial ovarian cancer and its clinical significance

28

Determining Surgical Resection Margin of Cancer by Rapid Molecular Assessment Using Mass Spectrometric Imaging

29

Hyperthermia and immune modulation in homologous recombination stratified epithelial ovarian cancer: Development of targeted therapeutic approaches

30

The phase 2 study of HIPEC and the proposed phase 3 RCT comparing between HIPEC and IP chemotherapy.

31

A prospective study to elucidate molecular genetic risk factors of gallbladder carcinoma in Indian Population

32

Role of nuclear receptors in pathogenesis of carcinoma gall bladder

33

Molecular and Genetic Analysis of TNBC

34

Hyperthermia and immune modulation in homologous recombination stratified epithelial ovarian cancer: Development of targeted therapeutic approaches

35

The phase 2 study of HIPEC and the proposed phase 3 RCT comparing between HIPEC and IP chemotherapy.

36

Role of nuclear receptors in pathogenesis of carcinoma gall bladder

37

Study of a Surrogate Panel of Immunohistochemical and Molecular Markers to Classify Human Colorectal Carcinomas as per the Consensus Molecular Subtypes and Clinical Correlation

 

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