Research Project
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RESEARCH
FUNDED PROJECTS
Ongoing
| 
 S.No. 
  | 
 Titleofthe project  | 
 NameofPrincipal Investigator  | 
 Fundedby(Name orfundingagency)  | 
 Duration years  | 
 Startyear  | 
 Endyear  | 
 Totalfunds Sanctioned(Rs)  | 
| 
 1.  | 
 Regional Virus Research and Diagnostic Laboratory (RL-VRDL)  | 
 Dr. Lalit Dar  | 
 Department of Health Research (DHR)  | 
 10 years (extendable)  | 
 2019  | 
 Continuous  | 
 ~ 5 crore  | 
| 
 2.  | 
 External Quality Assurance Scheme (EQAS) of National HIV/AIDS Reference Laboratory, AIIMS, Delhi  | 
 Dr. Bimal Kr. Das  | 
 NACO  | 
 Continuous  | 
 2005  | 
 Continuous  | 
 Approx. 14 lacs/annum  | 
| 
 3.  | 
 HIV integrated counseling and testing (ICTC)  | 
 Dr. Bimal Kr. Das  | 
 NACO  | 
 Continuous  | 
 2005  | 
 Continuous  | 
 Kits are provided by NACO and the rest is taken care of under EQAS budget  | 
| 
 4.  | 
 CD4 testing program  | 
 Dr. Bimal Kr. Das  | 
 NACO  | 
 Continuous  | 
 2005  | 
 Continuous  | 
 Testing kits provided by NACO, Rs. 50,000/- for Consumables  | 
| 
 5  | 
 Evaluation of NF- κB based reactivation of latency in HIV infected individuals who are on antiretroviral therapy for more than 15 years: A Quest for Cure.  | 
 Dr. Shesh Prakash Maurya (under mentorship of Bimal Kumar Das).  | 
 Funded by DHR (HRD scheme)  | 
 3 years  | 
 2022  | 
 2025  | 
 Rs. 50,92,497/-  | 
| 
 6  | 
 Evaluation of role of B-1 cells in modulating the response of T cells in HIV infected patients pre and post antiretroviral therapy: cohort study.  | 
 Dr. Bimal Kumar Das  | 
 Funded by ICMR  | 
 3 years  | 
 2022  | 
 2025  | 
 Rs. 50,40,572/-  | 
| 
 7  | 
 Nodal coordinating center for surveillance network of antimicrobial resistance in salmonella enterica serotype Typhi and Paratyphi 
  | 
 Dr. Bimal Kumar Das  | 
 Funded by ICMR  | 
 2 YEAR  | 
 2018  | 
 2024  | 
 2,39, 22,040  | 
| 
 8  | 
 Detection of salmonella serovars and their associated resistance marker directly from blood specimen using paper based DNA biosensor  | 
 Dr. Bimal Kumar Das  | 
 Funded by ICMR  | 
 2 YEAR  | 
 2024  | 
 2026  | 
 1,35,68,808  | 
| 
 9  | 
 Proteomics study of Giardia intestinalis isolates to associate with different clinical spectrum and extrapolate its invasive potential  | 
 Dr. B.R Mirdha  | 
 ICMR  | 
 3 years  | 
 Sept, 2023  | 
 August, 2026  | 
 48 lakhs  | 
| 
 10  | 
 Characterization of human antibody responses to Plasmodium vivax in India”. (Through Inspire faculty programme)  | 
 Dr. B.R Mirdha  | 
 Department of Science and Technology  | 
 5 years  | 
 August , 2023  | 
 2028  | 
 More than 5 Cr.  | 
| 
 11  | 
 ICMRs: Advanced Mycology Diagnostic and Research Centre (AMDRC)  | 
 Prof Immaculata Xess  | 
 ICMR  | 
 5 years  | 
 2022  | 
 2027  | 
 250 lakhs  | 
| 
 12  | 
 Multi-centric study on prevalence of Mycoplasma genitalium and its resistance markers in the high–risk group (MSM and FSW) attending sexually transmitted disease cclinics in North India.  | 
 Benu Dhawan  | 
 ICMR  | 
 3 years  | 
 December2021  | 
 December 2024  | 
 28.65 Lakhs  | 
| 
 13  | 
 Towards point of care test development for Bacterial Vaginosis, a polymicrobial infection.  | 
 Dr. Seema Sood  | 
 ICMR  | 
 3 years  | 
 2020  | 
 2023  | 
 51 Lakhs  | 
| 
 14  | 
 Exploring SELEX technology for potential POCT development for Genital Chlamydia trachomatis.  | 
 Dr. Seema Sood  | 
 ICMR  | 
 3 years  | 
 2022  | 
 2025  | 
 50 Lakhs  | 
| 
 15  | 
 Point-of-care test development for Bacterial Vaginosis (BV): Bench to bedside (Clinical validation of proof-of-concept).  | 
 Dr. Seema Sood  | 
 ICMR  | 
 3 years  | 
 2024  | 
 2027  | 
 75 Lakhs  | 
| 
 16  | 
 Mapping hotspots of MDR-TB in Assam, Sikkim and Tripura using Genomics approaches  | 
 Dr. Urvashi B. Singh  | 
 DBT-NER  | 
 3 years  | 
 2018  | 
 2024  | 
 ~ 4 Cr  | 
| 
 17  | 
 Epidemiological impact and intersection of the COVID-19 and Tuberculosis Pandemics in Brazil, Russia, India and South Africa  | 
 Dr. Urvashi B. Singh  | 
 DST  | 
 2 years  | 
 2021  | 
 2023  | 
 1.72 Cr  | 
| 
 18  | 
 Validation of Indigenously Developed Diagnostic kit based on Detection of Proteomic markers from Urine for Diagnosis of Pulmonary and Extra-pulmonary Tuberculosis  | 
 Dr. Urvashi B. Singh  | 
 ICMR  | 
 3 years  | 
 2022  | 
 2025  | 
 1.4 cr  | 
| 
 19  | 
 Operational Feasibility and performance of indigenous phenotypic kit for detection of multidrug resistant tuberculosis and extensively drug resistant tuberculosis in field setting under the National Tuberculosis Elimination program  | 
 Dr. Urvashi B. Singh  | 
 ICMR  | 
 3 years  | 
 2022  | 
 2025  | 
 14 lakhs  | 
| 
 20  | 
 Development of Surface Plasmon Resonance Array Biosensor for Rapid Molecular Drug Resistance Detection for MDR and XDR TB  | 
 Dr. Urvashi B. Singh  | 
 ICMR  | 
 2 years  | 
 2023  | 
 2025  | 
 40 Lakhs  | 
| 
 21  | 
 Development of Surface Enhanced Raman Scattering (SERS) Based Biosensor for Rapid Detection of oligonucleotides in MDR and XDR-TB.  | 
 Dr. Urvashi B. Singh  | 
 AIIMS-IITD  | 
 2 years  | 
 2022  | 
 2024  | 
 10 Lakhs  | 
| 
 22  | 
 A Preclinical Study to evaluate synergistic action of Rifampicin with Faropenem and Cefdinir on persister Mycobacterium tuberculosis bacilli in mouse model.  | 
 Dr. Urvashi B. Singh  | 
 AIIMS-THSTI  | 
 2 years  | 
 2023  | 
 2025  | 
 10 Lakhs  | 
| 
 23  | 
 To determine the prevalence of common virulence determinants associated with Uropathogenic Escherichia coli from community-setting at different geographical regions of India using phenotypic and genotypic methods  | 
 Dr. Sarita Mohapatra  | 
 ICMR  | 
 3 year  | 
 2022  | 
 2025  | 
 Rs553400.00  | 
| 
 24  | 
 Platform for discovery of novel therapeutic monoclonal antibodies against MDR and XDR Klebsiella pneumoniae  | 
 Sarita Mohapatra (Co-PI)/year  | 
 DBT-BIRAC  | 
 3 years  | 
 2023  | 
 2026  | 
 Rs. 4,88,840.00  | 
| 
 25  | 
 Micro-nano structured urinary catheter to minimize catheter-associated urinary tract infection  | 
 Sarita Mohapatra (Co-PI)  | 
 MoE-STARS  | 
 3 years  | 
 2023  | 
 2026  | 
 Rs 32.6 lacs  | 
| 
 26  | 
 National Program for the Surveillance of Viral Hepatitis 
  | 
 Dr. Aashish Choudhary  | 
 Ministry of Health & Family Welfare (MoHFW)  | 
 5 years (extendable)  | 
 2020  | 
 Continuous  | 
 ~ 1.3 crore  | 
| 
 27  | 
 NACO Regional Reference Laboratory for HIV viral load (VL)  | 
 Dr. Aashish Choudhary  | 
 National AIDS Control Organization (NACO)  | 
 No fixed duration  | 
 2019  | 
 Continuous  | 
 ~ 51 lakhs 
  | 
| 
 28  | 
 NACO Regional Reference Laboratory for HIV early infant diagnosis (EID)  | 
 Dr. Aashish Choudhary  | 
 National AIDS Control Organization (NACO)  | 
 No fixed duration  | 
 2012  | 
 Continuous  | 
 ~ 93 lakhs  | 
| 
 29  | 
 Whole genome sequencing of the SARS-CoV-2 novel coronavirus strains at a tertiary care center in Delhi.  | 
 Dr. Aashish Choudhary  | 
 AIIMS Delhi (Intramural grant)  | 
 2 years  | 
 2020  | 
 2023  | 
 ~ 11 lakhs  | 
| 
 30  | 
 Molecular Epidemiology and In-Vitro Antifungal Susceptibility of Cryptic Aspergillus species from Clinical and Environment samples  | 
 Dr. Gagandeep Singh  | 
 ICMR  | 
 3 years  | 
 2022  | 
 2025  | 
 35 lakhs  | 
| 
 31  | 
 Genomic profiling of invasive and hospital acquired Escherichia coli pathotypes from different clinical samples to identify the virulence and antimicrobial resistance markers  | 
 Dr. Hitender Gautam  | 
 Science & Engineering Research Board SERB (Under DST)  | 
 2 years 6 months  | 
 Mar 2022  | 
 Sept 2024  | 
 45,45,816/-  | 
| 
 32  | 
 Site-specific biomarkers to differentiate infection from either colonization or aseptic inflammation in ICU  | 
 Dr. Hitender Gautam  | 
 ICMR  | 
 3 years  | 
 Jan 2023  | 
 Dec 2025  | 
 73,39,362/-  | 
| 
 33  | 
 Molecular Characterization of diarrheagenic Escherichia coli among children with acute diarrhea: Association of virulence and adherence genes.  | 
 AIIMS Site PI: Dr. Hitender Gautam  | 
 Department of Health Research (DHR)  | 
 3 years  | 
 Jan 2024  | 
 Dec 2026  | 
 20,42,367/-  | 
| 
 34  | 
 PlatPlatform for enhanced pathogen detection for meningitis and sepsis: Rapid, portable, and field-deployable diagnostics. IIRPIG-2023-0001405  | 
 AIIMS Site PI: Dr. Hitender Gautam  | 
 ICMR  | 
 4 years  | 
 Mar 2024  | 
 Feb 2027  | 
 93,46,030/-  | 
| 
 35  | 
 Detection of viable but non-culturable (VBNC) Gram-negative bacteria in sepsis and meningitis: Clinical significance in AMR stewardship  | 
 AIIMS Site PI: Dr. Hitender Gautam  | 
 AIIMS-THSTI Collaborative Project  | 
 2 years  | 
 Dec 2023  | 
 Dec 2025  | 
 10 Lakhs  | 
| 
 36  | 
 Antimicrobial susceptibility patterns of pathogens isolated in bloodstream infections vis a vis antibiotic prescribing practices and genotypic clonality of Acinetobacter baumannii in various patient care units/areas  | 
 Dr. Hitender Gautam  | 
 Inter-Disciplinary AIIMS IMRG.  | 
 1 year  | 
 Jan 2024  | 
 Jan 2025  | 
 4,90,350/-  | 
| 
 37  | 
 Clinical and epidemiological study of Lyme disease: a multi-centric taskforce study in India  | 
 Dr. Nishant Verma  | 
 ICMR  | 
 3  | 
 2020  | 
 2023  | 
 3,86,71,240/-  | 
| 
 38  | 
 Proteomics study of Giardia intestinalis isolates to associate with different clinical spectrum and extrapolate its invasive potential  | 
 Dr. Nishant Verma  | 
 ICMR  | 
 3  | 
 2023  | 
 2026  | 
 48,69,222  | 
| 
 39  | 
 Expanded viral etiological investigation of genital ulcer disease with phenotyping and genotyping for antiviral drug resistance in herpes simplex viruses  | 
 Dr. Megha Brijwal  | 
 ICMR  | 
 3 years  | 
 2023  | 
 2026  | 
 ~ 59 lakhs  | 
| 
 40  | 
 Strengthening Capacity for Genomic Sequencing of Outbreak Prone Respiratory Pathogens like Influenza and Other Respiratory Viruses  | 
 Dr. Megha Brijwal  | 
 CDC & APHL, USA  | 
 5 months  | 
 2023  | 
 2023  | 
 ~ 40 lakhs  | 
| 
 41  | 
 Quantification of JC polyomavirus in CSF in patients with suspected progressive multifocal leukoencephalopathy (PML) by digital PCR  | 
 Dr. Megha Brijwal  | 
 AIIMS Delhi (Intramural grant)  | 
 1 year  | 
 2023  | 
 2024  | 
 ~ 5 lakhs  | 
| 
 42  | 
 Non-tubercular mycobacteria responsible for pulmonary disease and infections in procedures involving prosthetic devices, laparoscopy or following other interventions.  | 
 Dr. Kiran Bala  | 
 AIIMS, Intramural  | 
 1 year  | 
 2023  | 
 2024  | 
 4.95 Lakhs  | 
| 
 43  | 
 Detection of Mycoplasma pneumoniae infections in acute exacerbation of Chronic Obstructive Pulmonary Disease  | 
 Dr. Tanu Sagar  | 
 AIIMS Intramural  | 
 2 years  | 
 2024  | 
 2026  | 
 9.8 Lakhs  | 
Completed
| 
 S.No.  | 
 Titleofthe project  | 
 NameofPrincipal Investigator  | 
 Fundedby (Name offundingagency)  | 
 Duration (years)  | 
 Startyear  | 
 Endyear  | 
 Totalfunds sanctioned(Rs)  | 
| 
 1  | 
 Comparison of diagnostic accuracy of Real time PCR versus Nugent’s scoring in Indian women with and without Bacterial Vaginosis (BV). Award of SRFship  | 
 Dr. Seema Sood  | 
 ICMR  | 
 3 years  | 
 2019  | 
 2022  | 
 16.6 Lakhs  | 
| 
 2  | 
 Early Bactericidal Activity (EBA) of Rifampicin and Feropenem in Tuberculosis (Rifampicin Susceptible)-  | 
 Dr. Urvashi B. Singh  | 
 ICMR  | 
 2 Years  | 
 2019  | 
 2022  | 
 70 Lakhs  | 
| 
 3  | 
 Early Bactericidal Activity (EBA) and Pk/Pd Study of Rifampicin Feropenem Cefdinir with Clavulanate vs Standard of Care in Newly Diagnosed Smear Positive Rifampicin Susceptible TB  | 
 Dr. Urvashi B. Singh  | 
 ICMR  | 
 2 Years  | 
 2019  | 
 2023  | 
 70 Lakhs  | 
| 
 4  | 
 Rapid Molecular Drug Resistance Detections for MDR and XDR-TB and Molecular Typing of Mycobacterium Tuberculosis From Ziehl-Neelsen’s Stained Microscopic Slides From Delhi State.  | 
 Dr. Urvashi B. Singh  | 
 ICMR  | 
 3 Years  | 
 2018  | 
 2022  | 
 ~ 60 Lakhs  | 
| 
 5  | 
 Diagnosis of Pulmonary And Extra-Pulmonary Tuberculosis Patients Using Differentially Expressed Proteins As Potential Biomarkers: An Approach Towards Development Of Point Of Care Test.  | 
 Dr. Urvashi B. Singh  | 
 ICMR  | 
 3 Years  | 
 2018  | 
 2022  | 
 60 lakhs  | 
| 
 6  | 
 Crohn’s Disease in India: A multicenter study from a country where intestinal tuberculosis as well as Johne’s disease is endemic.  | 
 Dr. Urvashi B. Singh  | 
 ICMR/DHR  | 
 5 Years  | 
 2016  | 
 2022  | 
 35 lacs  | 
| 
 7  | 
 In vitro susceptibility of Cefiderocol against carbapenem-resistant gram-negative bacilli from patients with blood stream infection/sepsis, urinary tract infection or pneumonia  | 
 Dr. Sarita Mohapatra  | 
 Funded (Intramural)  | 
 2yr  | 
 2021  | 
 2023  | 
 9.7lacs  | 
| 
 8  | 
 Implementation of An Institutional Antifungal Stewardship Program (AFSP) On The Appropriate Use Of Antifungal Therapy And Outcomes In Patients With Invasive Fungal Infections.  | 
 Dr. Gagandeep Singh  | 
 ICMR  | 
 3 years  | 
 2020  | 
 2023  | 
 48 lakhs  | 
| 
 9  | 
 Study of hyaline non-sporulating moulds isolated from clinical samples of tertiary care respiratory hospital in Delhi  | 
 Dr. Gagandeep Singh  | 
 ICMR  | 
 3 years  | 
 2021  | 
 2024  | 
 27 lakhs  | 
| 
 10  | 
 Magnitude of asymptomatic malaria infections in pregnant women in a community hospital  | 
 Dr. Nishant Verma  | 
 AIIMS, New Delhi  | 
 1  | 
 2018 
  | 
 2019 (work continued in previous year too)  | 
 4,98,000/-  | 
| 
 11  | 
 A prospective study of viral infections in hematopoietic stem cell transplant recipients at a tertiary care hospital in India  | 
 Dr. Megha Brijwal  | 
 ICMR  | 
 3 years  | 
 2019  | 
 2023  | 
 45 lakhs  | 
| 
 12  | 
 Point of care Urinary Lipoarabinomannan antigen (LAM) detection as a diagnostic tool for Extra-pulmonary tuberculosis.  | 
 Dr. Kiran Bala  | 
 AIIMS, Intramural  | 
 2 year  | 
 2021  | 
 2023  | 
 4.94 Lakhs  | 
| 
 13  | 
 Changing epidemiology of tuberculosis among SARS CoV-2 pandemics.  | 
 Dr. Kiran Bala  | 
 AIIMS, Intramural  | 
 2 year  | 
 2021  | 
 2023  | 
 7.14 Lakhs  | 




