Dr. Ethayathulla Abdul Samath
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Dr. Ethayathulla Abdul Samath |
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Additional Professor R.No.3006, 3rd Floor Teaching Block
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Recent employment details |
Additional Professor,since July 2020-Till date |
Research Interests |
The research work is focused on TP53 tumor suppressor gene plays crucial role in suppression of cancer. But the mutation in p53 leads to tumour proliferation sometimes drug resistance cancer cells. The research focused on targeting mutant p53 with structure-based drug design to restore mutant p53 to functional like wild type. We do structure-based drug design by X-ray crystallography and for drug binding and functional studies we various biophysical techniques like ITC, CD, Fluorescence and cell based functional assay in p53 mutant cell lines. The second major project in our lab is antimicrobial drug development against drug resistant bacterial pathogen. We work on bacterial cell division proteins particularly FtsZ and its associate proteins involved forming divisome protein complex assembly. We do structure-based drug design by X-ray crystallography, In silico drug screening and for drug binding studies we various biophysical techniques like ITC, CD, Fluorescence. |
Any additional information |
Associate Professor (2017 - till date): Biophysics, AIIMS, New Delhi, India Assistant Professor (2014 – 2017): Biophysics, AIIMS, New Delhi, India Research Associate (2012-2014): Texas Tech University Health Science center, Texas, USA Post doctoral Fellow (2007 - 2012): University of California San Diego, California, USA. Ph.D. (Biophysics, 2007: AllMS, New Delhi Master of Science (Biophysics, 2002): University of Madras, Chennai Bachelor of Science (Physics -2000): University of Madras, Chennai Google scholar https://scholar.google.com/citations?user=KZJOecsAAAAJ&hl=en Pubmed https://www.ncbi.nlm.nih.gov/pubmed/?term=Ethayathulla+AS%5BAuthor%5D RCSB:
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Awards and Honors |
Senior Research Fellowship awarded by CSIR, New Delhi, India. Senior Research Fellowship in the project from DST, New Delhi, India. Junior Research Fellowship in the project from DST, New Delhi, India. Junior Research Fellowship in the project from DBT, New Delhi, India. |
Recent Publications
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