Dr. Jyoti

Dr. Jyoti

Scientist-I

Department of Pharmacology

A.I.I.M.S, New Delhi-110029

डॉ. ज्योति

वैज्ञानिक-I

भेषजगुण विज्ञान विभाग,

अ. भ. आ. सं., नई दिल्ली-110029

 

Contact Details: 4th Floor, Department of Pharmacology, Teaching Block, All India Institute of Medical Sciences (AIIMS), New Delhi 110029

Telephone: 011-26593677

Email ID: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Education:

• B.Sc. from Lucknow University, Lucknow

• M.Sc (Biotechnology) from Babasaheb Bhimrao Ambedkar University, Lucknow

• Ph.D in Life Sciences from Central Drug Research Institute, Lucknow

 

Research Interest/ area:

Endocrinology, Neurosciences

 

Past Position:

• Research associate (THSTI), Haryana, India (June 2021 – Oct 2023)

• Research associate (CDFD), Hyderabad, India (November 2019 – June 2020)

• Postdoctoral research associate (University of Georgia), Georgia, USA (May 2017 – July 2019)

• Postdoctoral research associate (University of Minnesota), Minnesota, USA (December 2015-April 2017)

 

Selected Publications:

1. Gautam J, Kumari D, Aggarwal H, Gupta SK, Kasarla SS, Sarkar S, Priya MRK, Kamboj P, Kumar Y, Dikshit M. Characterization of lipid signatures in the plasma and insulin-sensitive tissues of the C57BL/6J mice fed on obesogenic diets. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Jun 5;1868(9):159348.

2. Gautam J, Xu L, Nirwane A, Nguyen B, Yao Y. Loss of mural cell-derived laminin aggravates hemorrhagic brain injury. J Neuroinflammation. 2020 Apr 6;17(1)

3. Gautam J.,Cao Y. & Yao Y. Pericytic Laminin Maintains Blood-Brain Barrier Integrity in an Age-Dependent Manner. Transl. Stroke Res. (2019), Jun 18.

4. Gautam J, Miner JH, Yao Y. Loss of Endothelial Laminin α5 Exacerbates Hemorrhagic Brain Injury. Transl Stroke Res. 2019 Jan 29.

 5.   Gautam J, Nirwane A, Yao Y. Roles of Pericytes in Stroke Pathogenesis. Cell Transplant. 2018 Dec;27(12):1798-1808. 

6. Gautam J, Khedgikar V, Kushwaha P, Choudhary D, Nagar GK, Dev K, Dixit P, Singh D, Maurya R, Trivedi R. Formononetin, an isoflavone, activates AMP-activated protein kinase/β-catenin signalling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss. Br J Nutr. 2017 Mar;117(5):645-661.

7. Gautam J, Nirwane A, Yao Y.Laminin differentially regulates the stemness of type I and type II pericytes. Stem Cell Res Ther. 2017 Feb 7;8(1):28

8. Gautam J, Zhang X, Yao Y. The role of pericytic laminin in blood brain barrier integrity maintenance. Sci Rep. 2016 Nov 3;6:36450.

9. Gautam J, Kumar P,Kushwaha P, Khedgikar V, Choudhary D, Singh D, Maurya R, Trivedi R. (2015) Neoflavonoid dalbergiphenol from heartwood of Dalbergia sissoo acts as bone savior in an estrogen withdrawal model for osteoporosis. Menopause.;22(11):1246-55.

10. Gautam J, Choudhary D, Khedgikar V, Kushwaha P, Singh RS, Singh D, Tiwari S, Trivedi R. (2014) Micro-architectural changes in cancellous bone differ in female and male C57BL/6 mice with high-fat diet-induced low bone mineral density.Br J Nutr. 111(10):1811-21