Dr. Mahendra Seervi's Lab
(Cell Death and Cancer Biology Lab)
(Cell Death and Cancer Biology Lab)
Recent Publications:
- Heat shock proteins-driven stress granule dynamics: Yet another avenue for cell survival. (review article) Akanksha Verma, Sumi S, Mahendra Seervi Apoptosis, May 2021; doi: 10.1007/s10495-021-01678-w
- Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathway. Mahendra Seervi*, Sumi S, Aneesh Chandrasekharan, Abhay K. Sharma, T. R. Santhosh Kumar. (*Corresponding author) Cellular oncology, May 2019.doi: 10.1007/s13402-019-00451-1
- ROS mediated ER stress induces Bax-Bak dependent and independent apoptosis in response to Thioridazine. Mahendra Seervi*, Ankita Rani, Abhay K. Sharma, T. R. Santhosh Kumar. (*Corresponding author) Biomedicine & Pharmacotherapy, 2018; doi.org/10.1016/j.biopha.2018.06.123.
- Biosynthesised composites of Au-Ag nanoparticles using Trapa peel extract induced ROS mediated p53 independent apoptosis in cancer cells. Naheed Ahmad, Abhay K. Sharma, Seema Sharma, Imran khan, Dhananjay K. Sharma, Ayesha Shamsi, T. R. Santhosh Kumar, Mahendra Seervi* (*Co-corresponding author) Drug and Chemical Toxicology, 2018; doi: 10.1080/01480545.2018.1463241.
Book Chapter:
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Mitochondrial cell death pathways in Caenorhabiditis elegans.
Mahendra Seervi*, Ding Xue. (*Co-corresponding author)
Current Topics in Developmental Biology, 2015;114: 43-65.doi:10.1016 /bs.ctdb.2015.07.019.
Other important publications:
- A high-throughput image-based screen for the identification of Bax/Bak-independent caspase activators against drug-resistant cancer cells. Mahendra Seervi, Praveen K. Sobhan, Krupa Ann Mathew, Jeena Joseph, Prakash R. Pillai, Santhosh kumar T. R. Apoptosis, 2014; 19(1):269-84. doi: 10.1007/s10495-013-0921-8
- ERO1α dependent endoplasmic reticulum - mitochondrial calcium flux contributes for ER stress and mitochondrial permeabilisation by procaspase-activating compound (PAC-1). Mahendra Seervi, P K. Sobhan, Jeena Joseph, Krupa Ann Mathew, Santhosh Kumar T.R. Cell Death & Disease, 2013; 4, e968. doi:10.1038/cddis.2013.502
- Essential requirement of cytochrome c release for caspase activation by procaspase activating compound defined by cellular models. Mahendra Seervi, Jeena Joseph, P K. Sobhan, Bhavya B.C., Santhosh Kumar T.R. Cell Death & Disease, 2011; 2, e207. doi:10.1038/cddis.2011.90
- Identification of Heat Shock Protein 90 inhibitors to sensitize drug resistant side population tumor cells using a cell-based assay platform. Praveen K. Sobhan, Mahendra Seervi, Jeena Joseph, Bhavya B.C., Saneesh Varghese, Santhosh Kumar T.R. Cancer Letters, 2012; 317(1):78-88. doi: 10.1016/j.canlet.2011.11.009
For other publications, follow the link below:
https://scholar.google.com/citations?user=Gz_HQYoAAAAJ&hl=en