Dr. Rupesh K. Srivastava's Lab
Translational Immunology, Osteoimmunology & Immunoporosis Lab (TIOIL)
Translational Immunology, Osteoimmunology & Immunoporosis Lab (TIOIL)
Grants Awarded
- Principal Investigator (PI) – Indian Council of Medical Research (ICMR) Grant of 6.8 Cr. INR on " Investigating the Diagnostic Potential of Gut-Associated Metabolites in Post-Menopausal Osteoporotic Women and Exploring Their Therapeutic Potential in Pre-Clinical Model of Osteoporosis: An Osteoimmunological Approach”, 2024-2027 (Approved).
- Co-Principal Investigator (Co-PI) – DBT-Welcome India Alliance TEAM Grant of 9.57 Cr. INR on “Identification of key ligand/ligand complexes fo Plasmodium falciparum merozoite using Cyro-EM, proteome and immunological approaches - A Step towards the development of an efficacious malaria blood stage vaccine”, 2023-2028.
- Principal Investigator (PI) – CCRH-AYUSH Grant of 70 Lacs INR on “To investigate the bone protective potential of selected homeopathic formulations (SHFs) in osteoporotic conditions”, 2022-2025.
- Principal Investigator (PI) – Department of Biotechnology (DBT) Grant of 82 Lacs INR on "To elucidate the immunomodulatory role of probiotics in modulating bone health in post-menopausal osteoporosis via its effect on ILC3-ILCreg cell axis", 2021-2024.
- Principal Investigator (PI) - Indian Council of Medical Research (ICMR) Grant of 73 Lacs INR on "To investigate the therapeutic potential of probiotics in treatment and management of osteoporosis: “Role of regulatory B cells (Bregs)”, 2022-2025.
- Principal Investigator (PI) - Science and Engineering Research Board (SERB)-Extra Mural Research Grant of 65 Lacs USD (Department of Science and technology, Govt. of India) on "Elucidation of Cellular mechanisms involving GUT resident regulatory T cells in Probiotics mediated inhibition of Osteoporosis", 2018-2022.
- Principal Investigator (PI) – CSR funding from Unique Biotech, Hyderabad of 10 Lacs INR on “To dissect the Immunomodulatory potential of Probiotics in ameliorating acute respiratory distress syndrome (ARDS)”, 2022-2024.
- Principal Investigator (PI) – AIIMS-University College London Collaborative Research Grant of 10 Lacs INR on “To investigate the therapeutic potential of extracellular vesicles (EV) released by human induced pluripotent stem cell (hiPSC)-derived mesenchymal stem cells (iMSCs) to counteract oestrogen deficiency induced bone deterioration”, 2022-2023.
- Principal Investigator (PI) – AIIMS-Interdisciplinary Research Grant of 20 Lacs INR on “A comparative study to evaluate the effect of first line therapies in Osteoporotic patients”, 2023-2025.
- Principal Investigator (PI) – AIIMS-Intra Mural Research Grant of 10 Lacs INR on “To establish the role of Th9 cells in the pathophysiology of Osteoporosis”, 2022-2024.
- Principal Investigator (PI) – AIIMS-Interdisciplinary Research Grant of 20 Lacs INR on “To investigate the regulatory potential of Estrogen in modulating differentiation and function of regulatory B cells: Implications in bone remodeling”, 2021-2023.
- Principal Investigator (PI) – AIIMS-Interdisciplinary COVID-19 Research Grant of 10 Lacs INR on “To investigate the long-term impact of COVID-19 on bone health”, 2021-2022.
- Principal Investigator (PI) – AIIMS-Intra Mural Research Grant of 10 Lacs INR on “To establish the role of regulatory B cells (Bregs) in post-menopausal Osteoporosis”, 2020-2022.
- Principal Investigator (PI) - AIIMS-IIT-Delhi Inter Institutional Collaborative Research Grant of 20 Lacs INR on “Development of novel mushroom based synbiotic food supplement for management of Osteoporosis”,2019-2021.
- Principal Investigator (PI) - AIIMS-Intra Mural Research Grant of 10 Lacs INR on “To Dissect the role of Treg-Th17 cells in Lactobacillus rhamnosus mediated inhibition of Bone loss in ovx mice”, 2018-2020.
- Principal Investigator (PI) - University Grant Commission
(UGC)-Start Up Grant (06 Lacs INR) on Effect of regulating “mammalian Target of Rapamycin” (mTOR) activity on RANKL induced Osteoclastogenesis, 2014-2016.