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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Publications & Patents

Publication -2022

 

  1. Kandi, R., Sachdeva, K., Choudhury, S. D., Pandey, P. M., & Mohanty, S. (2022). A facile 3D bio‐fabrication of customized tubular scaffolds using solvent‐based extrusion printing for tissue‐engineered tracheal grafts. Journal of Biomedical Materials Research Part A. DOI: 10.1002/jbm.a.37458

  2. Majood, M., Rawat, S., & Mohanty, S. (2022). Delineating the role of extracellular vesicles in cancer metastasis: A comprehensive review. Frontiers in Immunology, 13. DOI: 10.3389/fimmu.2022.966661

  3. Gupta S, Krishnakumar V, Soni N, Rao EP, Banerjee A, Mohanty S. Comparative proteomic profiling of Small Extracellular vesicles derived from iPSCs and tissue specific mesenchymal stem cells. Exp Cell Res. 2022 Sep 17:113354. doi: 10.1016/j.yexcr.2022.113354. Epub ahead of print. PMID: 36126717.

  4. Naina Soni, Aarti T, Mukherjee, A Banerjee, Mohanty S. Bone marrow-derived extracellular vesicles modulate the abundance of infiltrating immune cells in the brain and exert an antiviral effect against the Japanese Encephalitis virus. FASEB BioAdvances, September 2022 https://doi.org/10.1096/fba.2022-00071

  5. Majood M, Shakeel A, Agarwal A, Jeevanandham S, Bhattacharya R, Kochhar D, Singh A, Kalyanasundaram D, Mohanty S, Mukherjee M. Hydrogel nanosheets confined 2D rhombic ice: a new platform enhancing chondrogenesis. Biomed Mater. 2022 Sep 15;17(6). doi: 10.1088/1748-605X/ac8e43. PMID: 36044885.

  6. Misba M, Piyush G , Mohanty S, M Mukherjee. Carbon Quantum Dots for Stem Cell Imaging and Deciding the Fate of Stem Cell Differentiation. ACS Omega. Aug 2022 DOI: 10.1021/acsomega.2c03285

  7. Deepak K Sahel, Mohanty S, D Chitkara. Cationic Lipopolymeric Nanoplexes Containing CRISPR/Cas9 Ribonucleoprotein for Genome Surgery. Journal of Materials Chemistry B August 2022 DOI: 10.1039/D2TB00645F

  8. Nidhi Nautiyal Deepanshu Maheshwari Mohanty S restoring bone marrow hematopoietic stem cells (BM-HSC) reserve augments regression of fibrosis and regeneration in animal model of cirrhosis. Journal of Hepatology July 2022 DOI: 10.1016/S0168-8278(22)01828-1

  9. Ratul Datta Ritwik Datta Santanu Rana Mohanty S Cardiomyocyte-specific regression of nitrosative stress-mediated S-Nitrosylation of IKKγ alleviates pathological cardiac hypertrophy. Cellular Signalling July 2022.98(3):11040 DOI: 10.1016/j.cellsig.2022.110403

  10. Dash S, Shakeel A, Mohanty S, Impact of nanotechnology on the realm of stem cells and regenerative medicine. ChemNanoMat. 2022 https://doi.org/10.1002/cnma.202200177

  11. Gupta S, Rawat S, Krishnakumar V, Rao EP, Mohanty S. Hypoxia preconditioning elicit differential response in tissue specific MSCs via immuno-modulation and exosomal secretion. Cell and Tissue Research. 2022. DOI: 10.1007/s00441-022-03615-y

  12. Sarangthem V, Sharma H, Mendiratta M, Sahoo RK, Park RW, Kumar L, Singh TD, Mohanty S. Application of bio-active ELP on regulation of human mesenchymal stem

  13. cell behaviour. Biomedicine. 2022. DOI: 10.3390/biomedicines10051151

  14. Bhardwaj R, Kumar L, Chhabra D, Mohanty S, Sharma A, Mehra NK, Kochupillai V. Effect of fetal liver condition media derived cytokines (IL-6 and Flt-3) on human bone marrow stem cells colony formation. Cytokine. 2022; 153 (155863). doi: https://doi.org/10.1016/j.cyto.2022.155863.

  15. Sen A, Singh A, Roy A, Mohanty S, Naik N, Kalaivani M, Ramakrishnan L. Role of endothelial colony forming cells (ECFCs) Tetrahydrobiopterin (BH4) in determining ECFCs functionality in coronary artery disease (CAD) patients. Scientific Report. 2022; 12 (3076). doi: https://doi.org/10.1038/s41598-022-06758-8.

  16. Sarangthem V, Sharma H, Goel R,GhoseS, Park RW, Mohanty S, Chaudhuri TK, Dinda AK, Singh TD. Application of Elastin-like Polypeptide (ELP) Containing Extra-cellular Matrix (ECM) Binding Ligands in Regenerative Medicine. International Journal of Biological Macromolecules. 2022; 207: 443-453. doi: https://doi.org/10.1016/j.ijbiomac.2022.03.018.

  17. Kumar A, Kumar D, Maheshwari D, Nautiyal N, Shubham S, Rooge S, Anand L, Vyas A, Kumari R, Sharma S, Bihari C, Mohanty S, Maiwall R, Sarin SK. Defects in energy metabolism are associated with functional exhaustion of bone marrow mesenchymal stem cells in cirrhosis. American Journal of Stem Cells. 2022; 11(1): 12-27.

  18. Dash S, Pinky, Arora V, Sachdeva K, Sharma H, Dinda AK, Agrawal AK, Jassal M, Mohanty S. Promoting in-vivo bone regeneration using facile engineered load-bearing 3D bioactive scaffold. Biomedical Materials. 2022; 17(3). doi: https://doi.org/10.1088/1748-605X/ac58d6.

  19. Sen A, Thakkar H, Vincent V, Rai S, Singh A, Mohanty S, Roy A, Ramakrishnan L. Endothelial colony forming cell (ECFC) tetrahydrobiopterin level in coronary artery disease patients and its association with circulating endothelial progenitor cells. Canadian Journal of Physiology and Pharmacology. 2022. doi: 10.1139/cjpp-2021-0548.

  20. Gupta S, Pinky, Vishal, Sharma H, Soni N, Rao EP, Dalela M, Yadav A, Nautiyal N, Kumar A, Nayak B, Banerjee A, Dinda AK, Mohanty S. Comparative evaluation of anti-fibrotic effect of tissue specific Mesenchymal Stem Cells derived Extracellular vesicles for the amelioration of CCl4 induced chronic liver injury. Stem Cell Reviews and Reports. 2022; 18(3): 1097-1112. doi: 10.1007/s12015-021-10313-9.

 

 

Publication – 2021

 

  1. 1. Soni N, Gupta S, Rawat S, Krishnakumar V, Mohanty S, Banerjee A. MicroRNA enriched exosomes from different sources of Mesenchymal Stem Cells can differentially modulate functions of immune cells and neurogenesis. Biomedicines. 2021; 10(1): 69. doi: https://doi.org/10.3390/biomedicines10010069.

  2. 2. Raghav PK, Mann Z, Ahalawat S, Mohanty S. Mesenchymal stem cell-based nanoparticles and scaffolds in regenerative medicine. European Journal of Pharmacology. 2021; 174657. doi: 10.1016/j.ejphar.2021.174657.

  3. 3. Rawat S, Dadhwal V, Mohanty S. Dexamethasone priming enhances stemness and immunomodulatory property of tissue-specific human mesenchymal stem cells. BMC Developmental Biology. 2021; 21(16). doi: https://doi.org/10.1186/s12861-021-00246-4.

  4. 4. Sachdeva K, Kumar A, Mohanty S. Virology of SARS-CoV-2 and Management of nCOVID-19 utilizing Immunomodulation properties of Human Mesenchymal Stem Cells. Stem Cell Investigation. 2021; 8: 23. doi: 10.21037/sci-2020-040.

  5. 5. Ganger A, Singh A , Kalaivani M , Gupta N, Vanathi M, Mohanty S and Tandon R. Outcomes of Surgical Interventions for the Treatment of Limbal Stem Cell Deficiency. Indian Journal of Medical Research. 2021; 154(1): 51-61. doi: 10.4103/ijmr.IJMR_1139_18.

  6. 6. Poddar D, Majood M, Singh A, Mohanty S, Jain P. Chitosan coated pore wall polycaprolactone three-dimensional porous scaffolds for bone tissue engineering: a comparison study with blending technique to fabricate scaffolds. Progress in Biomaterials. 2021; 10(4): 281-297. doi: 10.1007/s40204-021-00172-5.7. Sharma Y, Ray S, Mohanty S. Wielding MSCs Derived Extracellular Vesicles as a Therapeutic Moiety for Neurodegenerative Disorders: A Viewpoint. BIOCELL. 2021; 46(6): 1435–1438. doi: 10.32604/biocell.2022.018612.

  7. 8.Panda B, Sharma Y, Gupta S, Mohanty S. Mesenchymal Stem Cell Derived Exosomes as an Emerging Paradigm for Regenerative Therapy and Nano-medicine: A Comprehensive Review. Life. 2021; 11(8):784. doi: 10.3390/life11080784.

  8. 9.Rawat S, Jain KG, Rawat S, Gupta D, Raghav P, Chaudhuri R, Pinky, Shakeel A, Arora V, Sharma H, Debnath D, Kalluri A, Agrawal A, Jassal M, Dinda AK, Patra P, Mohanty S. Graphene Nano-Fiber Composites for Enhanced Neuronal Differentiation of Human Mesenchymal Stem Cells. Nanomedicine. 2021; 16(22):1963-1982. doi: 10.2217/nnm-2021-0121.

  9. 10.Deedwania P, Deka D, Mohanty S, Dadhwal V, Sharma A. Isolation and characterization of mesenchymal stem cells derived from amniotic fluid: A prospective study. International Journal of Molecular & Immuno Oncology. 2021; 5(2); 67-72. doi:10.25259/IJMIO_22_2019.

  10. 11. Bhardwaj R, Kumar L, Chhabra D, Mehra NK, Sharma A, Mohanty S, Kochupillai V. In Vitro Expansion of Fetal Liver Hematopoietic Stem Cells. Scientific Reports. 2021;11(1):11879. doi: 10.1038/s41598-021-91272-6.

  11. 12. Sharma V, Rawat S, Gupta S, Tamta S, Sharma R, Seth T, Mohanty S. Human Acquired Aplastic Anemia Patients’ Bone-Marrow-Derived Mesenchymal Stem Cells are not Influenced by Hematopoietic Compartment and Maintain Stemness and Immune Properties. Anemia. 2021; 2021:6678067. doi: 10.1155/2021/6678067.

  12. 13. Yadav S, Takkar B, Prasad LV, Sen S, Kashyap S, Gupta D, Jassal M, Agrawal AK, Mohanty S, Tandon R. Experimental evaluation of safety & efficacy of plasma treated Poly-caprolactone membrane as a substitute for human amniotic membrane in treating corneal epithelial defect in Rabbit eye. Indian Journal of Ophthalmology. 2021; 69(9):2412-2416. doi: 10.4103/ijo.IJO_2986_20.

  13. 14. Renu V, Sen S, Mohanty S, Agarwal T, Kaur J, Vajpayee R, Sharma N. Prognostic Significance of Matrix Metalloproteinase 9 in Comet Operated Chronic Ocular Stevens Johnson Syndrome. British Journal of Ophthalmology. 2021; bjophthalmol-2021-319302. doi: 10.1136/bjophthalmol-2021-319302.

  14. 15. Poddar D, Jain P, Rawat S, Mohanty S. Influence of varying concentrations of chitosan coating on the pore wall of polycaprolactone based porous scaffolds for tissue engineering application. Carbohydrate Polymers. 2021; 259:117501. doi: 10.1016/j.carbpol.2020.117501

  15. 16. Sharma Y, Gupta S, Mohanty S. Stem cell exosome: Mesenchymal stem cell-derived exosome as a nano weapon to target the COVID-19 pandemic. BIOCELL. 2020; 45(3)21: 517-520. doi:10.32604/biocell.2021.014621.

 

 

Publication – 2020

 

  1. 1.Malhotra S, Dumoga S, Joshi A, Mohanty S, Singh N. Polymeric Micelles Coated with Hybrid Nanovesicles Enhance the Therapeutic Potential of the Reversible Topoisomerase Inhibitor Camptothecin in a Mouse Model. Acta Biomaterialia. 2020;121:579-591. doi: 10.1016/j.actbio.2020.11.049.

  2. 2.Kandi R, Pandey PM, Majood M, Mohanty S. Fabrication and characterization of customized tubular scaffolds for tracheal tissue engineering by using solvent based 3D printing on predefined template. Rapid Prototyping Journal. 2020; 27 (2): 421-428. doi: 10.1108/rpj-08-2020-0186.

  3. 3.Sharma S, Pandey NN, Sinha M, Kumar S, Jagia P, Gulati GS, Gond K, Mohanty S, Bhargava B. Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate Safety and Therapeutic Efficacy of Angiogenesis Induced by Intraarterial Autologous Bone Marrow-Derived Stem Cells in Patients with Severe Peripheral Arterial Disease. Journal of Vascular and Interventional Radiology. 2020; 32(2):157-163. doi: 10.1016/j.jvir.2020.09.003.

  4. 4.Sharma S, Pukale SS, Sahel DK, Agarwal DS, Dalela M, Mohanty S, Sakhuja R, Mittal A, Chitkara D. Folate-Targeted Cholesterol-Grafted Lipo-Polymeric Nanoparticles for Chemotherapeutic Agent Delivery. AAPS PharmSciTech. 2020; 21(7):280. doi: 10.1208/s12249-020-01812-y.

  5. 5.Pukale SS, Sharma S, Dalela M, Singh AK, Mohanty S, Mittal A, Chitkara D. Multi-component clobetasol-loaded monolithic lipid-polymer hybrid nanoparticlesameliorate imiquimod-induced psoriasis-like skin inflammation in Swiss albino mice. Acta Biomaterialia. 2020;115:393-409. doi: 10.1016/j.actbio.2020.08.020.

  6. 6.Singh M, Vaishnav PK, Dinda A, Mohanty S. Evaluation of Priming Efficiency of Forskolin in Tissue-Specific Human Mesenchymal Stem Cells into Dopaminergic Neurons: An In Vitro Comparative Study. Cells. 2020; 9(9):2058. doi: 10.3390/cells9092058.

  7. 7.Venugopal R, Nagpal R, Mohanty S, Sen S, Kashyap S, Agarwal T, Maharana P, Vajpayee R, Sharma N. Outcomes of Cultivated Oral Mucosal Epithelial Transplantation in eyes with Chronic Stevens-Johnson Syndrome Sequelae. American Journal of Ophthalmology. 2020; 222:82-91. doi: 10.1016/j.ajo.2020.08.022.

  8. 8.Kumar M,Mondithoka S,Mohanty S,Kamal VK,Selvi A,Bhoi S. Trends in granulocyte colony-stimulating factor following trauma hemorrhagic shock. International Journal of Critical Illness and Injury Science. 2020; 10(3): 1-7.doi: 10.4103/IJCIIS.IJCIIS_2_20.

  9. 9.Atwal P, Gupta S, Kumar V, Sharma Y, Dinda AK, Mohanty S. Mesenchymal Stem Cell-Derived Exosomes: A Nano Platform for Therapeutics and Drug Delivery In Combating COVID-19. Stem Cell Reviews and Reports. 2020;17(1):33-43. doi: 10.1007/s12015-020-10002-z.

  10. 10.Raghav PK, Mohanty S. Are graphene and graphene-derived products capable of preventing COVID-19 infection? Medical Hypotheses. 2020; 144:110031. doi: 10.1016/j.mehy.2020.110031.

  11. 11.Singh M, Singh A, Pandey P, Padma MV, Mohanty S. Application of stem cells in Stroke: A multifactorial Approach. Frontiers in Neurosciences. 2020; 14:473. doi: 10.3389/fnins.2020.00473.

  12. 12.Singh N, Shekhar B, Mohanty S, Girish B. Autologous bone marrow-derived stem cell therapy for Asherman's syndrome and endometrial atrophy: A 5-year follow-up study. J of Human Reproductive Sciences. 2020; 13(1):31-37. doi: 10.4103/jhrs.JHRS_64_19.

  13. 13.Thanusha AV, Mohanty S, Dinda AK, Koul V. Fabrication and evaluation of gelatin/hyaluronic acid/chondroitin sulfate/asiatic acid based biopolymeric scaffold for the treatment of second degree burn wounds–Wistar rat model study. Biomedical Materials. 2020; 15(5):055016. doi: 10.1088/1748-605X/ab8721.

  14. 14.Midha S, Jain KG, Bhaskar N, Kaur A, Rawat S, Giri S, Basu B, S Mohanty. Tissue‐specific mesenchymal stem cell‐dependent osteogenesis in highly porous chitosan‐based bone analogs. STEM CELLS Translational Medicine. 2020;10(2):303-319. doi: 10.1002/sctm.19-0385.

  15. 15.Sharma P, Jain KG, Pandey PM, Mohanty S. In vitro degradation behavior, cytocompatibility and hemocompatibility of topologically ordered porous iron scaffold prepared using 3D printing and pressure less microwave sintering. Materials Science and Engineering: C. 2020; 106:110247. doi: 10.1016/j.msec.2019.110247.

  16. 16.Sybil D, Jain V, Mohanty S, Husain SA. Oral stem cells in intraoral bone formation. Journal of Oral Biosciences. 2020; 62(1):36-43. doi: 10.1016/j.job.2019.12.001

     

    Patents   

    Granted (01): 

     

    1. Superior and simple method to isolate very small embryonic-like stem cells (VSELs) without the Use of Flow Cytometry: Patent Number 287658

     

    Filed (03):  

     

    2. Bone Substitute and method for preparation thereof. Date of filing:11.03.2022, Application number: 202211013471, O/Ref: SUJA001IN

     

    3. Single-step method for synthesizing biocompatible fluorescent magnetic nanoparticle for biomedical application and biomaterial labelled therewith. Date of filing:30.06.2022, Application number: 202211037664, O/Ref: SUJA002INP 

     

    4. A Bio composite, composition thereof and method of preparation therefor. Date of filing:08.07.2022, Application number: 202211039429, O/Ref: SUJA003INP

     

     

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