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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Research

 PUBLICATIONS (2022-2023) 

  1. Ahmed J, Bir R, Bala K, Singh UB. The COVID-19 pandemic does not bode well for TB control. The International Journal of Tuberculosis and Lung Disease 2022; 26 (9): 897-901.

  2. Ahmed J, Rawre J, Dhawan N, Dudani P, Khanna N, Dhawan B. Genital ulcer disease: A review J Family Med Prim Care 2022;11:4255-62.

  3. Ahmed J, Singh G, Mohan A, Agarwal R, Sachdev J, Khullar S, Xess I et al. Invasive pulmonary aspergillosis infection in severely ill COPD patients in pulmonary ward and ICU. Indian J Med Microbiol. 2022 Mar 12:S0255-0857(22)00042-1. doi: 10.1016/j.ijmmb.2022.02.006. Epub ahead of print. PMID: 35292163.

  4. Ahuja J, Soneja M, Wig N, Biswas A, Xess I, Singh G, et al. Cryptococcal antigenemia in people living with HIV and AIDS. Int J STD AIDS. 2023 Feb;34(2):130-136.

  5. Bagga S, Krishnan A, Dar L. Revisiting live attenuated influenza vaccine efficacy among children in developing countries. Vaccine. 2023 Jan 3:S0264-410X(22)01594-8. doi: 10.1016/j.vaccine.2022.12.058.

  6. Bala K, Xess A, Das R, Singla N, Seth A, Singh UB. Diagnosis and successful treatment of unusual presentation of Urogenital tuberculosis. Access Microbiology 2022; 000488. v1.

  7. Bamola VD, Kapardar R, Lal B, Sharma A, Chaudhry R. A metagenomic assessment of gut microbiota in Indian colon cancer patients. J Cancer Res Ther. 2022 Jan-Mar;18(1):96- 102. doi: 10.4103/0973-1482.341139. IF 1.331

  8. Batra P, Gopi S, Vinayraj EV, Saikiran KVP, Ahmed J, Pathak P, Gunjan Det al. A rare case of complicated pancreatitis due to leptospirosis. Indian Journal of Medical Microbiology 2022: 40 (4): 602-604.

  9. Bhattacharya A, Gupta S, Verma R, Das BK, Kapil A, Singh R, and Sood S. Detection of Neisseria gonorrhoeae in Genital and Extragenital Sites in Men Who Have Sex With Men in India. Sex Transm Dis 2023; 50(2): 128

  10. Bir R, Gautam H, Arif N, Chakravarti P, Verma J, Banerjee S, Das B, et al. Analysis of colistin resistance in carbapenem-resistant Enterobacterales and XDR Klebsiella pneumoniae. Ther Adv Infectious Dis 2022;9: 1–15.

  11. Bir R, Mohapatra S, Kumar A, Ahmed N, Tyagi S, Pius A, Gautam H, Sood S, et al. Genomic analysis of Fosfomycin resistance in multi-drug resistant uropathogens and comparison of in-vitro susceptibility methods uropathogens. Iranian J of Microbiology, 2022: 14(5): 636-44.

  12. Bir R, Mohapatra S, Kumar A, Arif N, Tyagi S, Pius AK, Gautam H, et al. Genomic analysis of Fosfomycin resistance in multi-drug resistant uropathogens and comparison of in-vitro susceptibility methods uropathogens. Iran J Microbiol Oct 2022;14(5):636-644. http://ijm.tums.ac.ir

  13. Bir R, Mohapatra S, Kumar A, Arif N, Tyagi S, Pius AK, et al. Genomic analysis of Fosfomycin resistance in multi-drug resistant uropathogens and comparison of in-vitro susceptibility methods uropathogens. Iran J Microbiol2022;14:636-644.

  14. Biswal D, Mirdha BR. Acanthamoeba meneingoencephalitis in an immunocmopent patient –World J Med Images Videos 2022,8: e44-53

  15. Biswal D, Mirdha BR. A case of atypical vivax malaria with a global review of reports on myriads of morphovariatios in parasitsed red blood cells. Access Microbiology,2023: 5: 000461v3 DDI 10.1099/acmi.o.000461.v3

  16. Biswal D, Verma N, Mirdha BR. A serendipitous inhabitant in the ileum detected during bowel surgery in a case of high-grade urothelial carcinoma. World J Med Images Videos Cases 2022; 8: e80-4.

  17. Biswal D, Verma N, Mirdha BR. Atypical diagnostic consideration - from a GI tract parasitic infection to unusual onsite contamination. World J Med Images Videos Cases 2022; 8: e93-96.

  18. C Padmapriydarsini, M Mamulwar, A Mohan, P Shanmugam, UB Singh. Randomized trial of metformin with anti-tuberculosis drugs for early sputum conversion in adults with pulmonary tuberculosis. Clinical Infectious Diseases 2022; 75 (3): 425-434.

  19. Challa A, Kachhawa G, Sood S, Upadhyay AD, Dwivedi SN, Gupta S. Correlates of bacterial vaginosis among women from North India. Int J STD AIDS. 2022 Jun;33(7):666-671. doi: 10.1177/09564624221091743.

  20. Challa A, Mahajan N, Sood S, Kapil A, Das BK, Sreenivas V and Gupta S. Azithromycin resistance and its molecular characteristics in Neisseria gonorrhoeae isolates from a tertiary care centre in North India. Ind J Med Microbiol. 2022; 40(3): 433-35.

  21. Challa A, Mahajan N, Sood S, Kapil A, Das BK, Sreenivas V, et al. Azithromycin resistance and its molecular characteristics in Neisseria gonorrhoeae isolates from a tertiary care centre in North India. Indian J Med Microbiol. 2022;40(3):433-5.

  22. CK Thakur, P Batra, EV Vinayaraj, K Sreenath, N Rathor, UB Singh, et al. Scrub typhus in two COVID-19 patients: a diagnostic dilemma. Future Microbiology 2022; 17 (3): 161-167.

  23. Das A, Vidyarthi AJ, Khan S, Singh S, Bala K, Wundavalli LT, Singh UB, et al. Persistence of SARS-CoV-2 in COVID-19 patients during the second wave of the pandemic in India. The Journal of Infection in Developing Countries 2022; 16 (06): 959-965.

  24. Das R, Gupta V, Khullar S, Verma N, Mirdha BR. Seropositivity Pattern of Human Cystic Echinococcosis at a Tertiary Care Hospital of India. J Lab Physicians 2023; 15:169–172.

  25. Das R, Gupta V, Khullar S, Verma N, Mirdha BR. Seropositivity Pattern of Human Cystic Echinococcosis at a Tertiary Care Hospital of India. J Lab Physicians. 2023 Feb 6;15(1):169-172. doi: 10.1055/s-0042-1758662. PMID: 37064974; PMCID: PMC10104716.

  26. Das S, Gajula VP, Mohapatra S, Kar S, Bhatt S,Singh G, et al. Antimicrobial efficacy of argon cold atmospheric pressure plasma jet on clinical isolates of multidrug-resistant ESKAPE bacteria, IEEE Transactions on Radiation and Plasma Medical Sciences, doi: 10.1109/TRPMS.2023.3235358.

  27. Das S, Gajula VP, Mohapatra S, Singh G, Kar S. Role of cold atmospheric plasma in microbial inactivation and the factors affecting its efficacy. Health Sciences Review [Internet]. 2022 Sep 1;4.

  28. Desai D, Khan AR, Soneja M, Mittal A, Naik S, KodanP,Dar L, et al. Effectiveness of an inactivated virus-based SARS-CoV-2 vaccine, BBV152, in India: a test-negative, case-control study. Lancet Infect Dis. 2022 Mar;22(3):349-356. doi: 10.1016/S1473-3099(21)00674-5. Epub 2021 Nov 23. PMID: 34826383; PMCID: PMC8610201.

  29. ESGMAC-MyCOVID Study Team. Mycoplasma pneumoniae detections before and during the COVID-19 pandemic: results of a global survey, 2017 to 2021. Eurosurveillance. 2022 May 12;27(19):2100746.IF.6.307

  30. Ganduri B, Sujith R, Tirlangi P, Nalla R,Singh G, Xess I, et al. Disseminated Medicopsisromeroi infection in a kidney transplant recipient: A case report. J Mycol Med. 2022 Dec 5;33(2):101355.

  31. Goda R, Sharma R, Borkar SA, Katiyar V, Narwal P, Ganesh Kumar A, Mohapatra S, et al. Frailty and Neutrophil Lymphocyte Ratio as predictors of mortality in patients with CAUTI or CLABSI in the Neurosurgical ICU: Insights from a Retrospective Study in a Developing Country. World Neurosurg. 2022;162:e187-e197

  32. Goel N, Singh R, Sood S and Khare SK. Investigation of Streptomyces sp. Strain EMB24 Secondary Metabolic Profile Has Unraveled Its Extraordinary Antibacterial Potency Against Drug-Resistant Bacteria. Marine Biotechnology, 2022; 24: 1168-75.

  33. Gupta G, Shareef I, Tomar S, Kumar MSN, Pandey S, Sarda R, et al. Th1/Th2/Th17 Cytokine Profile among Different Stages of COVID-19 Infection. Natl Acad Sci Lett. 2022;45(4):363-9.

  34. Joshi RK, Sarangi SC, Mohapatra S, Mallick S, Datta SK. A Comparative Review of ICMR, WHO, and EMA Guidelines for Good Clinical Laboratory Practices. Indian J of Lab Physician 2022 DOI https://doi.org/ 10.1055/s-0042-1757237.

  35. Kanodia A, Bhalla AS, Singh G, Xess I, Valappil BV, Kakkar A, et al. The Role of Serum Galactomannan Assay as a Potential Surrogate Biomarker for Fungal Microinvasion in Allergic Fungal Rhinosinusitis. Indian J Otolaryngol Head Neck Surg. 2023 Mar;75(1):49-53.

  36. Kaushik A, Bandyopadhyay S, Porwal C, Srinivasan A, Singh UB, et al. 2D-DIGE based urinary proteomics and functional enrichment studies to reveal novel Mycobacterium tuberculosis and human protein biomarker candidates for pulmonary tuberculosis. Biochemical and Biophysical Research Communications 2022;

  37. Khullar S, Das R, Verma N, Mohammad T, Gammalgati S, Makharia G, Mirdha BR. Photo Quiz: A 22-Year-Old with Abdominal Pain. J Clin Microbiol. 2022 Jul 20;60(7):e0208721. doi: 10.1128/jcm.02087-21. Epub 2022 Jul 20. PMID: 35856698; PMCID: PMC9297830.

  38. Khullar S, Das R, Verma N, Mohammad T, Gammalgati S, Makharia G, Mirdha BR. Answer to July 2022 Photo Quiz. J Clin Microbiol. 2022 Jul 20;60(7):e0210321. doi: 10.1128/jcm.02103-21. Epub 2022 Jul 20. PMID: 35856697; PMCID: PMC9297809.

  39. KP Angitha , Mohapatra S , Gautam H , Nityadarshini N , Das BC and Yadav VK. The Gram stain: Implication in blood culture reporting. Tropical Doctor 2022, 1–4.

  40. KP Kumar, AS Bhalla, A Goyal, P Naranje, R Guleria, A Mohan, UB Singh. Aspergilloma morphology on CT angiography and its clinical impact in patients of haemoptysis. Current Problems in Diagnostic Radiology 2022.

  41. Kumar A, Mohapatra S, Bir R, Tyagi S, Bakhshi S, Mahapatra M, et al. Intestinal Colonization Due to Carbapenem-Resistant Enterobacteriaceae Among Hematological Malignancy Patients in India: Prevalence and Molecular Charecterisation. Indian J Hematol Blood Transfus. 2022;38(1):1-7.

  42. Kumar A, Mohapatra S, Bir R, Tyagi S, Bakhshi S, Mahapatra M, Kapil A et al. Intestinal Colonization Due to Carbapenem-Resistant Enterobacteriaceae Among Hematological Malignancy Patients in India: Prevalence and Molecular Charecterisation. Indian J Hematol Blood Transfus. 2022 Jan;38(1):1-7. doi: 10.1007/s12288-021-01415-y. Epub 2021 Feb 24. PMID: 35125706.

  43. Mahalingam K, Angmo D, Kakkar A, Bafna RK, Sharma T, Rai A,Dar L, et al. Analysis of SARS-CoV-2 in Corneal Tissue of Deceased Asymptomatic Novel Coronavirus Disease 2019 Donors. Cornea. 2022 Dec1;41(12):1559-1563. doi: 10.1097/ICO.0000000000003127. Epub 2022 Sep 28.PMID:36197341.

  44. Mala R, Sood S, Kapil A, Gupta S, Singh N. Comparison of Amsel's criteria with low and high Nugent's scores for the diagnosis of bacterial vaginosis. Indian J Sex Transm Dis 2022;43:56-8.

  45. Malhotra S, Gupta S, Sood S. Selection of DNA aptamers against Neisseria gonorrhoeae causing sexually transmitted infection (STI). Molecular Biotechnology.https://doi.org/10.1007/s12033-023-00688-0.

  46. Maurya SP, Sharma A, Singh R, Gautam H, Das BK. HIV testing & diagnosis in 2020 at the apex tertiary referral hospital of India: impact of COVID-19 pandemic. AIDS Care. 2022;34(7):828-31.

  47. Maurya SP, Singh R, Sinha S, Gautam H, Das BK. A study on HIV infected individuals who reported CD4+ cell count below 100 cells/ µl multiple times after more than 6 months of anti-retroviral therapy at the apex tertiary referral hospital of India. Indian Journal of Sexually Transmitted Diseases and AIDS 2022 Jul-Dec;43(2):216-218. doi: 10.4103/ijstd.ijstd_103_21.

  48. Mohan A, Bhatnagar A, Gupta T, Ujjalkumar D, Kanswal S, Velpandian T, Singh UB. Early pharmacokinetic evaluation of anti-tubercular treatment as a good indicator of treatment success in pulmonary tuberculosis patients on a retreatment regimen. Journal of Pharmaceutical Investigation 2022; 1-11.

  49. Mohapatra S, Panigrahy R, Tak V, J V S, K C S, Chaudhuri S, et al. Prevalence and resistance pattern of uropathogens from community settings of different regions: an experience from India. Access Microbiol. 2022; 4(2):000321. doi: 10.1099/acmi.0.000321.

  50. Mohapatra S, Ghosh D, Vivekanandan P, Chunchanur S, Venugopal S, Tak V, et al.investigators of CAUTION-ED STUDY (Community-acquired UTI & Emerging Drug Resistance). Genome profiling of uropathogenic E. coli from strictly defined community-acquired UTI in paediatric patients: a multicentric study. Antimicrobial Resistance & Infection Control2023;12:36. https://doi.org/10.1186/s13756-023-01233-z

  51. Mohapatra S, Venugopal SJ, Kalaivani M, Kant S, Tak V, Panigrahy R, et al. Antibiotic Resistant of uropathogen among the community-Dwelling pregnant and non-pregnant female :a step toward antibiotic stewardship BMC Infectious Dis 2022;22:239.

  52. Muthu V, Agarwal R, Rudramurthy S, Thangaraju D, Shevkani M, Singh G, et al. Multicenter Case–Control Study of COVID-19–Associated Mucormycosis Outbreak, India. Emerg Infect Dis. 2023;29(1):8-19.

  53. Negi N, Maurya SP, Singh R, Das BK. An update on host immunity correlates and prospects of re-infection in COVID-19. Int Rev Immunol. 2022;41(4):367-92.

  54. Ningombam A, Acharya S, Sarkar A, Kumar K, Brijwal M, Routray S, et al. Evaluation of sensitivity and specificity of high fluorescence lymphocyte count percentage of sysmex XN analyzer in diagnosis of dengue. J Appl Hematol 2022;13:132-8.

  55. Nityadarshini N, Mohapatra S, Gautam H, Jain V, Chaudhry R, Kapil A. Polymicrobial growth in standard urine culture: Time to Act or Ignore? Tropical Doctor. 2022 Apr;52(2):335-336. DOI: 10.1177/00494755221076909.

  56. Pangti R, Gupta S, Bhari N, Dhawan B, Gupta S. Lichenoid secondary syphilis as immune reconstitution inflammatory syndrome with mixed etiology genital ulcer in a human immunodeficiency virus-positive patient. Indian J Sex Transm Dis AIDS 2022;43(1):86-87.

  57. Potdar V, Brijwal M, Lodha R, Yadav P, Jadhav S, Choudhary ML, Dar L, et al. Identification of Human Case of Avian Influenza A(H5N1) Infection, India. Emerg Infect Dis. 2022; Jun 28(6):1269-1273. doi: 10.3201/eid2806.212246. PMID: 35608874; PMCID: PMC9155886.

  58. Quraishi R, Sarkar S, Parmar A, Jain R, Das BK, Ambekar A. Exploring the clinical variables among drug-dependent HIV-Positive patients: Implications for treatment strategies. Indian J Public Health. 2022;66(3):331-3.

  59. Raj JS, Rawre J, Dhawan N, Khanna N, Dhawan B. Mycoplasma genitalium: A new superbug. Indian J Sex Transm Dis AIDS2022;43:1-12.

  60. Raj S, Sharma T, Pradhan D, Tyagi S, Gautam H, Singh H, et al. Comparative Analysis of Clinical and Genomic Characteristics of Hypervirulent Klebsiella pneumoniae from Hospital and Community Settings: Experience from a Tertiary Healthcare Center in India. MicrobiolSpectr. 2022;10(5):e0037622.

  61. Raj S, Sharma T, Pradhan D, Tyagi S, Gautam H, Singh H, Mohapatra S, et al. Comparative Analysis of Clinical and Genomic Characteristics of Hypervirulent Klebsiella pneumoniae from Hospital and Community Settings: Experience from a Tertiary Healthcare Center in India. Microbiol Spectr 2022;10(5):e0037622.

  62. Raj S, Sharma T, Pradhan D, Tyagi S, Gautam H, Singh H, Chaudhry R, et al. Comparative Analysis of Clinical and Genomic Characteristics of Hypervirulent Klebsiella pneumoniae from Hospital and Community Settings: Experience from a Tertiary Healthcare Center in India. Microbiology spectrum. 2022 Oct 26;10(5):e00376-22. IF.9.04

  63. Ramprasad A, Kodan P, Jonnalagadda K, Bir R, Verma N, Sahni K, Mirdha BR, et al. Seroprevalence of Strongyloides infection among steroid recipients in a tertiary care centre in North India. Infez Med. 2022 Dec 1;30(4):593-601. doi: 10.53854/liim-3004-15. PMID: 36482946; PMCID: PMC9715000.

  64. Rathor N, Thakur CK, Das BK, Chaudhry R. An insight into the therapeutic potential of a novel lytic Pseudomonas phage isolated from the river Ganga. J ApplMicrobiol. 2022 May 26. doi: 10.1111/jam.15639. Epub ahead of print. PMID: 35616159. IF. 4.059

  65. Ray A, Chowdhury M, Sachdev J, Sethi P,Singh G, Xess I, et al. Efficacy of LD Bio Aspergillus ICT Lateral Flow Assay for Serodiagnosis of Chronic Pulmonary Aspergillosis. J Fungi (Basel). 2022 Apr 14;8(4):400.

  66. Raza S, Das B, Chaudhry R, Goyal V, Lodha R, Kapil A, et al. Efficiency of Real-Time PCR in the Diagnosis of Community-Acquired Bacterial Meningitis in Children. J Microbiol Infect Dis. 2022; 12(02): 47-53.

  67. Relhan V, Sahay RR, Shete AM, Yadav PD, Sahoo B, Patil DY, Dar L, et al. Clinical presentation, viral kinetics, and management of human monkeypox cases from New Delhi, India 2022. J Med Virol. 2023 Jan;95(1):e28249. doi: 10.1002/jmv.28249.Epub 2022 Nov 2. PMID: 36271515.

  68. SaiKiran KVP, Biswal D, Agrawal SK, Batra P, Sagar T, Choudhary SK, Chaudhry R, et al. Anaerobes in cardiac infections: A decade experience from the tertiary care center. Indian J Med Microbiol. 2022 Apr-Jun;40(2):274-278. doi: 10.1016/j.ijmmb.2021.12.013. Epub 2022 Jan 12. PMID: 35031155.

  69. Samad SA, Jethani J, Kumar L, Choudhary A, Brijwal M, Dar L. Respiratory Syncytial Virus Infection among Adults after Hematopoietic Stem Cell Transplantation. J Glob Infect Dis. 2022;14(3):112-116. Published 2022 Aug 26. doi:10.4103/jgid.jgid_11_22.

  70. Sauteur PM, Chalker VJ, Berger C, Nir-Paz R, Beeton ML, ESGMAC and the ESGMAC– MyCOVID study group-Rama Chaudhry. Mycoplasma pneumoniae beyond the COVID-19 pandemic: where is it?. The Lancet. Microbe. 2022 Aug 11; IF. 86·208

  71. Sharma A, Gupta P, Ahmad A, Iyer VK, Malhotra N, Singh UB et al. Evaluation of implantation markers and immune cell infiltration in endometrial biopsy of female genital tuberculosis. Indian Journal of Tuberculosis 2022; 69 (4): 465-469.

  72. Sharma JB, Jain S, Dharmendra S, Singh UB, Soneja M, Kulshrestha V et al. An evaluation of Composite Reference Standard (CRS) for diagnosis of Female Genital Tuberculosis. Indian Journal of Tuberculosis 2022; 70 (1): 70-76.

  73. Sharma JB, Kumari S, Jaiswal P, Dharmendra S, Hari S, Singh UB. Hysterosalpingography observations in female genital tuberculosis with infertility. Journal of Human Reproductive Sciences 2022; 15 (4): 362.

  74. Sharma JB, Singh UB, Dharmendra S, Hari S, Purwar R. Role of Magnetic Resonance Imaging in evaluation of tuberculous tubo-ovarian mass. Indian Journal of Tuberculosis 2022: 69 (4): 539-545.

  75. Sharma M, Brijwal M, Chakraborty N, Choudhary A, Kumar A, Srivastav S, Dar L, et al. Rate of shed of SARS COV-2 viral RNA from COVID-19 cadavers. J Infect Public Health. 2022 Dec;15(12):1486-1493. doi: 10.1016/j.jiph.2022.11.001. Epub 2022 Nov 4. PMID: 36410269; PMCID: PMC9633634.

  76. Sharma N, Gautam H, Tyagi S, Raza S, Mohapatra S, Sood S, et al. Clinical use of multiplex‐PCR for the diagnosis of acute bacterial meningitis. J Family Med Prim Care 2022;11:593‐8

  77. Shende T, Singh G, Xess I, Khullar S, Yadav RK, Agarwal R, et al. Capsule-deficient cryptococcal meningitis: A diagnostic conundrum. J Global Infect Dis 2022;14:165-9.

  78. Singh R, Maurya SP, Das N, Kabra SK, Lodha R, Das BK. Immunological factors associated with discordant virological response post combination antiretroviral therapy in pediatric human immunodeficiency virus infection. Indian J Pharmacol. 2022;54(4):278-81.

  79. Sinha A, Mathew G, Arushi A, Govindarajan S, Ghanapriya K, Grewal N, et al. Sequential rituximab therapy sustains remission of nephrotic syndrome but carries high risk of adverse effects. Nephrol Dial Transplant. 2022 Jul 30; gfac228. doi: 10.1093/ndt/gfac228. Epub ahead of print. PMID: 36071552.

  80. Sinha B., Goyal N., Kumar M., Choudhary A., AryaA., Revi A., et al. Incidence of lab-confirmed dengue fever in a pediatric cohort in Delhi, India. PLoS Neglected Tropical Diseases. 2022; 16(4): e0010333. https://doi.org/10.1371/journal.pntd.001033.

  81. Sinha S, Ajayababu A, Thukral H, Gupta S, Guha SK, Basu A, et al. Efficacy of Bacillus Calmette-Guerin (BCG) Vaccination in Reducing the Incidence and Severity of COVID-19 in High-Risk Population (BRIC): a Phase III, Multi-centre, Quadruple-Blind Randomised Control Trial. Infect Dis Ther. 2022;11(6):2205-17.

  82. Sodhi J, Gupta A, Singh G, Singh G, Kumar R, Kapil A, et al. Preparation of operating room for COVID-19 suspects at a tertiary care teaching hospital in New Delhi, India. Int J Infection Control. 2022:180.

  83. Sreenath K, Kabra SK, Dey AB, Chandolia A, Sagar T, Singh V, Ghimire JJ, Guleria R, Chaudhry R. Mycoplasma pneumoniae among Hospitalized Patients with Acute Respiratory Tract Infections in an Indian Tertiary Care Hospital: an Underreported Health Problem. Microbiology Spectrum. 2022 Aug 31;10(4):e01589-22. IF.9.043

  84. Trajman A, Felker I, Alves LC, Coutinho I, Osman M, Meehan SA, Singh UB. The COVID-19 and TB syndemic: the way forward. The International Journal of Tuberculosis and Lung Disease 2022; 26 (8): 710-719.

  85. UB Singh, M Rophina, R Chaudhry, V Senthivel, K Bala, RC Bhoyar, et al. Variants of concern responsible for SARS‐CoV‐2 vaccine breakthrough infections from India. Journal of medical virology 2022; 94 (4): 1696-1700.

  86. UB Singh, M Singh, K Bala, A Srivastav, N Mahajan, S Sharma, et al. Expedited diagnosis of Pediatric Tuberculosis using Truenat MTB-Rif Dx and GeneXpert MTB/RIF. 2022

  87. UB Singh, S Deb, L Rani, D Bhardwaj, R Gupta, M Kabra, K Bala et al. Genomic surveillance of SARS-CoV-2 upsurge in India due to omicron sub-lineages BA. 2.74, BA. 2.75 and BA. 2.76. The Lancet Regional Health. Southeast Asia 2023;11: 100148.

  88. UB Singh, S Deb, R Chaudhry, K Bala, L Rani, R Gupta, L Kumari, et al. SARS-CoV-2 Omicron Variant Wave in India: Advent, Phylogeny and Evolution. bioRxiv32022.

  89. Vidyarthi AJ, Das A, Chaudhry R. Challenges in setting up a diagnostic microbiology laboratory during coronavirus disease 2019 crisis and impact on the diagnosis of communicable diseases. Indian Journal of Public Health. 2022 Apr 1;66(2):230. IF.2.219

  90. Vidyarthi AJ, Das A, Khan S, Panda S, Singh G, Thakar A, et al. Relevance of conventional microscopy in the diagnosis of mucormycosis during COVID-19 pandemic. J MicroscUltrastruct.

  91. Xess I, Singh G, Yadav RK, Pandey M, Sachdev J. COVID-19 Associated Mucormycosis: Ramping up our services during crisis. Indian J Med Microbiol. 2022 Apr 1:S0255-0857(22)00052-4.

  92. Yadav M, PundirS , Kumari R, Kumar A , Shwetha JV , Panigrahi R, et al. Variation in virulence genes as a differentiator of asymptomatic Vs symptomatic isolates: Insights from community-acquired Uropathogenic Escherichia coli. Microbiology2022;168:001161. DOI 10.1099/mic.0.001161.

  93. Yadav M, Pundir S, Kumari R, Kumar A, Venugopal SJ, Panigrahy R, Sood S, et al. Virulence gene mutations as a differentiator of clinical phenotypes: insights from community-acquired uropathogenic Escherichia coli. Microbiology (Reading)2022; 168(4). doi: 10.1099/mic.0.001161. PMID: 35380532.

  94. Yadav PD, Kaur H, Gupta N, Sahay RR, Sapkal GN, Shete AM… Dar L, et al. Zika: A vector borne disease detected in newer states of India amidst the COVID-19 pandemic. Front Microbiol2022 Jun 10;13:888195.

  95. Yadav RK, Singh G, SaiKiran KVP, Iram A, Rana B, Xess I. A study on candiduria in neonates and infants from a tertiary care center, North India, Indian Journal of Medical Microbiology2023; 42: 25-29.

  96. Yadav VS, Mohapatra S, Das BK, Gautam H, Kapil A. Infection due to drug-resistant Elizabethkingia Meningoseptica in a tertiary care hospital in India. India Journal of Applied Research 2022;12:16-17. Doi: 10.36106/ijar

 

FUNDED PROJECTS (2022-2023)  

S.No

Title of the project

1.

Clinical and Epidemiological study of Lyme disease: A multi-centric task force study in India

2.

Bacteriophage endolysins: An alternative strategy for MDR Acinetobacter spp.

3.

To determine the gut colonization of Clostridioides difficile, Vancomycin resistant Enterococci and Carbapenem resistant Enterobacteriaceac in recovered COVID cases.

4.

Regional Virus Research and Diagnosis Laboratory

5.

NACO Regional Reference Laboratory for HIV Viral Load (VL)

6.

NACO Referral Laboratory for HIV Early Infant Diagnosis (EID)

7.

Evaluation of NF- κB based reactivation of latency in HIV infected individuals who are on antiretroviral therapy for more than 15 years: A Quest for Cure

8.

Evaluation of role of B-1 cells in modulating the response of T cells in HIV infected patients pre and post antiretroviral therapy: cohort study.

9.

Evaluating immune mechanism leading to carrier stage in typhoid infection among Indian Population; prospective cohort study

10.

External Quality Assurance Scheme (EQAS) of National HIV/AIDS Reference Laboratory, AIIMS, Delhi

11.

Streptococcus pneumoniae and Hemophilus serotype distribution and antibiotic resistance in isolates from pediatric pneumonia cases in Assam

12.

Proteomic study of Giardia intestinalis isolates to associate with clinical spectrum different and extrapolate its invasive potential (ID-2021-143-65)

13.

ICMRs: Advanced Mycology Diagnostic and Research Centre (AMDRC)

14.

 

Multi-centric study on prevalence of Mycoplasma genitalium and its resistance markers in the high–risk group (MSM and FSW) attending sexually transmitted disease clinics in North India.

15.

Exploring SELEX technology for potential POCT development for Genital Chlamydia trachomatis.

16.

Towards point of care test development for Bacterial Vaginosis, a polymicrobial infection

17.

Rapid electrochemical detection of methicillin-resistant Staphylococcus aureus (MRSA) and azithromycin-resistant Neisseria gonorrhoeae (NG): A Novel Strategy (2021-2024))

18.

Epidemiological impact and intersection of the COVID-19 and Tuberculosis Pandemics in Brazil, Russia, India and South Africa

19.

Validation of Indigenously Developed Diagnostic kit based on Detection of Proteomic markers from Urine for Diagnosis of Pulmonary and Extra-pulmonary Tuberculosis

20.

Operational feasibility and performance of Indigenous phenotypic kit for detection of Multidrug resistant tuberculosis and extensively drug resistant tuberculosis in field settings under the National Tuberculosis Elimination Program

21.

Development of Surface Plasmon Resonance Array Biosensor for Rapid Molecular Drug Resistance Detection for MDR and XDR TB

22.

Development of Surface Enhanced Raman Scattering (SERS) based Biosensor for Rapid Detection of oligonucleotides in

MDR-TB and XDR-TB

23.

To determine the prevalence of common virulence determinants associated with UropathogenicEscherichia coli from community-setting at different geographical regions of India using phenotypic and genotypic methods

24.

In vitro susceptibility of Cefiderocol against carbapenem-resistant gram-negative bacilli from patients with blood stream infection/sepsis, urinary tract infection or pneumonia

25.

National Program for the Surveillance of Viral Hepatitis

26.

Molecular Epidemiology and In-Vitro Antifungal Susceptibility of Cryptic Aspergillus species from Clinical and Environment samples

27.

Implementation of An Institutional Antifungal Stewardship Program (AFSP) On The Appropriate Use Of Antifungal Therapy And Outcomes In Patients With Invasive Fungal Infections.

28.

Genomic profiling of invasive and hospital acquired Escherichia coli pathotypes from different clinical samples to identify the virulence and antimicrobial resistance markers

29.

Site-specific biomarkers to differentiate infection from either colonization or aseptic inflammation in ICU

30.

In vitro susceptibility of Isepamicin in clinical isolates of Enterobacteriaceae and its correlation with Aminoglycoside modifying enzyme resistance mechanism.

31.

Post exposure effect of COVID-19 infection on Nuclear factor kappa B (NF-кB) activity in immune cells: friend or foe in long term complications? Inter-Disciplinary for COVID-19 IMRG.

32.

Magnitude of asymptomatic malaria infections in pregnant women in a community hospital

33.

Clinical and epidemiological study of Lyme disease: a multi-centric taskforce study in India

34.

Expanded viral etiological investigation of genital ulcer disease with phenotyping and genotyping for antiviral drug resistance in herpes simplex viruses

35.

Strengthening Capacity for Genomic Sequencing of Outbreak Prone Respiratory Pathogens like Influenza and Other Respiratory Viruses

36.

Point of care Urinary Lipoarabinomannan antigen (LAM) detection as a diagnostic tool for

Extra-pulmonary tuberculosis.

37.

Changing epidemiology of tuberculosis among SARS CoV-2 pandemics.

 

 

 

COLLABORATIVE PROJECTS

Ongoing

S.No

Title of the project

Collaborating department/Institution

 

CDC-AIIMS Cooperative Agreement projects on Influenza and other respiratory viruses

Centre for Disease Control (CDC), Atlanta (USA) and Centre for Community Medicine, AIIMS

 

Rapid point of care detection of HPV-associated malignancies (National Cancer Institute, NIH, USA)

Department of Obstetrics and Gynaecology

 

To explore the association of enteric parasitic infections with duodenal eosinophilia in patients with Functional dyspepsia (DMID )

Gastroenterology, Pathology. Internal Medicine

 

Detection of malaria with special focus on submicroscopic malaria, among febrile patients, characterization of plasmodia species and correlation of clinical effects (MD)

Internal Medicine, Pediatrics

 

Utility of radiolabeled antibiotics as imaging agents in establishment of a decision support algorithm in patients with pyrexia of unknown origin (PUO) caused by infection and its impact on short term and long term clinical outcomes.

Department of Nuclear Medicine

 

A study on frequency, risk-factors and characteristics of sino-nasal mycobiome in COVID-19 associated mucormycosis.

Department of Medicine

 

 

Antifungal Effect of Lactoferricin, a natural potent antimicrobial peptide derived from the innate immunity protein, Lactoferrin and its use in the therapeutics of Mucormycosis.

Department of Biophysics

 

A preliminary study to validate BM-AspICU algorithm for diagnosing invasivepulmonary aspergillosis in critically ill ventilated patients using post-mortemminimally invasive tissue sampling.

Department of Medicine

 

 

National Capacity building program for healthcare workers in infection prevention and control (IPC) including biomedical waste (BMW) management for pandemic preparedness

Department of Hospital Administration

 

Role of 99m-Tc-Ubiquicidinscintigraphy in diagnosis of orthopaedic implant infection.

Department of Nuclear Medicine

 

Clinical and radiological outcomes of revision Joint replacement surgery in periprosthetic joint infections: An ambispective study.

Department of Orthopaedics

 

Analysis of vaginal microbiome and metabolome in women affected with bacterial vaginosis before and after treatment and their correlation with relapse or recurrences

Dermatology, AIIMS

 

Exploration of alternate salivary diagnostic strategies for ovarian cancer

Biophysics, AIIMS

 

A preliminary study to validate BM-AspICU algorithm for diagnosing invasive pulmonary aspergillosis in critically ill ventilated patients using post-mortem minimally invasive tissue sampling

Medicine, AIIMS

 

Incidence and characteristics of VAE in an adult ICU

Medicine, AIIMS

 

Studies on antimicrobial resistance

IIT, Delhi

 

A phase IIB Open label randomized controlled clinical trial to evaluate the anti-bacterial activity, pharmacokinetics, safety and tolerability of metformin when given along with nifampicin, isoniazid, pyrazinamide and ethambutol in adults with newly diagnosed sputum positive pulmonary tuberculosis: an 8- week study

Pulmonary Medicine and Sleep Disorders, AIIMS

 

Phase III, Randomized, Double blind , Placebo controlled Trial to Evaluate the Efficacy and Safety of VPM1002, Immunovac Vaccines in Preventing of Tuberculosis Disease in Healthy Household Contacts of Newly Diagnosed Sputum Positive Pulmonary TB (PTB) Patients Funded by ICMR, New Delhi; 2018-20

Pulmonary Medicine and Sleep Disorders, AIIMS

 

Role of tuberculosis and gentital Chalmydia trachomatis infection in women with “unexplained infertility”

Gynae & Obs

 

Efficacy of Energy Dense Nutritional Supplement (EDNS) as adjunct to standard DOTS therapy improving treatment outcomes in malnouristed newly diagnosed sputum positive pulmonary tuberculosis adult patients

Centre for Community Medicine (CCM)

 

Evaluation of newer molecular methods and antigen based diagnostic modalities against RNTCP recommended methods in early diagnosis of female genital tuberculosis

Gynae & Obs

 

Burden of multidrug-resistant neonatal sepsis in district hospital settings in India

Dept. of Paediatrics

 

In-vitro susceptibility of Eravacycline V/S tigecycline in clinical isolatres of XDR Acinetobacter baumannii and study of resistance mechanisms

Department of Microbiology

 

Developing an antibiogram based on culture samples of suspected patients of infection presenting to the emergency department

Emergency Medicine

 

Central line-associated bloodstream infections and bacterial contamination among health care workers in medical ICU: a prospective observational study

Dept. of Medicine

 

Acute diarrhoeal disease due to typical and atypical Enteropathogenic Escherichia coli among under-5 children

Dept. of Microbiology

 

A study of cytokines and the immune response in acute bacterial meningitis among paediatric patients

Dept. of Microbiology

 

Multi-drug resistant and Extensively drug resistant Enterobacterales- Prevalence, Treatment and Outcomes- A Prospective Observational study

Dept. of Medicine

 

Clinical profile & outcomes of ventilator associated pneumonia due to MDR & XDR gram-negative bacilli

Dept. of Medicine

 

AMR-Educate: A multinational and interdisciplinary research-integrated education partnership for a sustainable future against infection and antimicrobial resistance threat

International (Indo-Norway)

 

OH-AMR Diag: Novel technological solutions for rapid detection and screening of AMR from a One-Health perspective

International (Indo-Norway)

 

National Capacity Building for healthcare workers in Infection, Prevention and Control including biomedical waste management for pandemic. Funded by USAID & JHPIEGO

Department of Hospital Administration, AIIMS, New Delhi

 

APP-DIP: Development of AI based prognostic platform for an early detection of infections in immunocompromised patients. Jointly sanctioned under Indo-Sweden Collaboration in Biotechnology (IITD) & AIIMS, New Delhi. Indo(DBT)-Sweden Collaboration.

Indo-Sweden Collaboration in Biotechnology with IIT-D and Department of Medical Oncology, AIIMS, New Delhi

 

Metabolic resuscitation using early administration of ascorbic acid, thiamine and corticosteroids in perioperative management of surgical patients with septic shock: an exploratory Randomized Controlled trial.

Department of Surgery

 

Multi-centric prospective hospital based sentinel surveillance to determine the aetiology of acute bacterial meningitis in children

Central Research Laboratory, K.I.M.S. Hospital & Research Centre, Kempegowda Institute of Medical Sciences, Bangalore

 

Utility of Radiolabeled Antibiotics as Imaging Agents in Establishment of a Decision Support Algorithm in Patients with Pyrexia of Unknown Origin (PUO) caused by Infection and its Impact on Short Term and Long Term Clinical Outcomes

Department of Nuclear Medicine, AIIMS, New Delhi

 

Etiological profile of infants, children and adolescents presenting with acute, subacute and chronic encephalitis/encephalopathy in a tertiary care centre in North India

Division of Neurology, Department of Paediatrics, AIIMS, New Delhi

 

Effectiveness of Robot in floor cleaning for minimizing human exposure in view of COVID-19 pandemic.

Department of Hospital Administration, AIIMS, New Delhi

 

Determination of seroprevalence of COVID-19 IgG antibody among healthcare workers involved in Sanitation, housekeeping and Security services

Department of Hospital Administration, AIIMS, New Delhi

 

 

Research over past 3 years

Research project

2020-2021

2021-2022

2022-2023

Total Funded projects

49

62

43

Total Funding (Lakhs)

Rs.589.7 

Rs.869.4 

1179.46

 

 

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