Other Facilities

Therapeutic Drug Monitoring Facility: 

Therapeutic drug monitoring has become important for dose titration of many drugs of narrow therapeutic margin. Interpretation of TDM results should also take into consideration time of sample in relation to last dose, duration of treatment with the current dose, dosing schedule, age, gender, concomitant drug therapy, relevant disease states, reason for request e.g. lack of effect, routine monitoring, suspected toxicity, the patient’s response and the desired clinical target. It is important to remember that drug concentrations need to be interpreted in the context of the individual patient without rigid adherence to a therapeutic range.

The Department of Pharmacology in collaboration with the Department of Nephrology at All India Institute of Medical Sciences, has started therapeutic drug monitoring facility of several drugs for patient care and research. To  start with, antiepileptic drugs, immunosuppressants like cyclosporine, and methotrexate have been started for patient for patient care free of cost.

 In the year 2007-2008, the following samples were from different departments were done for patients free of cost:

LH – 35 patients

FSH 7 patients

E2 38 patients

Progesterone- 4 patients

Prolactin- 1 patient

Valproate- 65 patients

                                         i.     Autoanalyser

                                        ii.     PCR apparatus

                                      iii.     Laminar flow cabinet

                                      iv.     Western blot assembly

                                       v.     CO2 Incubator

                                      vi.     Inverted microscopes

                                    vii.     Water purification system

                                   viii.     HPLC

                                      ix.     Atomic absorption spectroscopy

                                       x.     Biopac System for EGG measurement.

                                      xi.     Centrifuge

                                    xii.     Homogenizer

                                   xiii.     Deep freezer (-20^oC)

                                  xiv.     Deep freezer (-70^oC)

                                    xv.     Spectrophotometer

                                  xvi.     PH meter

                                 xvii.     Hot Water Bath

                             xviii.     Refrigerators