Dr. Hariprasad G

Designation

Additional Professor

Email

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Contact Number

+91-11-26594240  

Educational Qualifications

M.D., Ph.D

Research Interests

Biomarker discovery; Structure Based Drug Design; Medical Education

Awards and Honors

Recent Significant Publications

Gupta AK, Pokhriyal R, Khan MI, Kumar DR, Gupta R, Chadda RK, Ramachanran R, Goyal V, Tripathi M, Hariprasad. G*. Cerebrospinal fluid proteomics for identification of α2-macroglobulin as a potential biomarker to monitor pharmacological therapeutic efficacy in dopamine dictated disease states of Parkinson’s disease and schizophrenia. Neuropsychiatric Disease Treatment. (2019) 15: 2853-2867

Gupta AK, Pokhriyal R, Das U, Khan MI, Kumar DR, Gupta R, Chadda RK, Ramachanran R, Goyal V, Tripathi M, Hariprasad. G*. Evaluation of α-synuclein and apolipoprotein E as potential biomarkers in CSF to monitor pharmaco-therapeutic efficacy in dopamine dictated disease states of Parkinson’s disease and schizophrenia. Neuropsychiatric Disease Treatment. (2019) 15: 2073-2085

Gupta AK, Kumar GK, Rani K, Pokhriyal R, Khan MI, Kumar DR, Goyal V, Tripathi M, Gupta R, Chadda RK, Vanamail P, Mohanty AK, Hariprasad. G*. 2D-DIGE as a strategy to identify serum protein biomarkers to monitor pharmacological efficacy in dopamine dictated states of Parkinson’s disease and schizophrenia. Neuropsychiatric Disease Treatment. (2019) 15: 1031-1044.

Gupta AK, Rani K, Swarnkar S, Kumar GK, Khan MI, Pokhriyal R, Kumar DR, Goyal V, Tripathi M, Gupta R, Chadda RK, Vanamail P, Hariprasad G*. Evaluation of Serum Apolipoprotein E as a Potential Biomarker for Pharmacological Therapeutic Efficacy Monitoring in Dopamine Dictated Disease Spectrum of Schizophrenia and Parkinson's disease: A Preliminary Study. J Cent Nerv Syst Dis. (2018) 10:1179573518803585. eCollection 

Sehrawat U, Pokhriyal R, Gupta AK, Hariprasad R, Khan I, Gupta D, Naru J, Singh SB, Mohanty AK, Vanamail P, Kumar L, Kumar S, Hariprasad G*. Comparative proteomic analysis of advanced ovarian cancer tissue to identify potential biomarkers of responders and non-responders to first line chemotherapy of carboplatin and paclitaxel. Biomarkers in Cancer (2016) 8:43-56

Khan MI, GuptaAK, KumaR, Ethayathulla AS, Kumar M, Hariprasad G*. Molecular modeling of Gly80 and Ser80 variants of human group IID phospholipase A2 and their receptor complexes: potential basis for weight loss in chronic obstructive pulmonary disease. Journal of Molecular Modeling (2016) 22:232

Hariprasad G, Hariprasad R, Kumar L, Srinivasan A, Srujana K, Kaushik A. Apolipoprotein A1 as a potential biomarker in the ascetic fluid for the differentiation of advanced ovarian cancers. (2013) Biomarkers. 18: 532-41.

Hariprasad G, Kota D, Singh SB, Srinivasan A, Adhikary S. Delineation of the structural elements of oriental liver fluke PLA₂ isoforms for potent drug designing.(2014) Indian J Clin Biochem. In Press

Hariprasad G, Srinivasan A, Singh R. Structural and phylogenetic basis for the classification of group III phospholipase A₂. (2013) J Mol Model. 19: 3779-91

Hariprasad G*, Kaur P, Srinivasan A, Singh TP, Kumar M. Structural analysis of secretory phospholipase A₂ from Clonorchis sinensis: therapeutic implications for hepatic fibrosis. (2012) J Mol. Model. 18: 3139-3145.

Hariprasad G*, Kaur P, Srinivasan A, Singh TP, Kumar M. Structural analysis of secretory phospholipase A₂ from Clonorchis sinensis: therapeutic implications for hepatic fibrosis. (2012) J Mol. Model. 18: 3139-3145

Hariprasad G, Kumar M, Rani K, Kaur P, Srinivasan A. (2012) Aminoglycoside induced nephrotoxicity: Molecular modeling studies of the calreticulin-gentamicin complex. J Mol. Model. 18: 2645-2652.

Hariprasad G, Kumar M, Srinivasan A, Kaur P, Singh TP, Jithesh O. (2011) Structural analysis of a group III Glu62-phospholipase A₂ from the scorpion, Mesobuthus tamulus: targeting and reversible inhibition by native peptides. Int. J Biol. Macromol. 48: 423–431.   

Hariprasad G, Srinivasan A, Vedakumari Y. (2011) Electrical conductivity as a tool to detect salt in clinical proteomics samples. Indian J Clin. Biochem. 26: 82-83.

Hariprasad G, Kumar M, Kaur P, Singh TP, Kumar RP. (2010) Human group III PLA₂ as a drug target: Structural analysis and inhibitor binding studies. Int. J Biol. Macromol. 47: 496-501   

Hariprasad G(2008) Rationale for student exposure to pre- and para medical sciences as part of internship. Med. Educ. 42: 645. 

Hariprasad G (2008) Holistic presentation of the under graduate medical  curriculum. Med. Educ. 42: 849.

Omicron Spike protein trimer model

Omicron Spike protein (RBD)_Human ACE-2 receptor complex model at 100ns MD