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अखिल भारतीय आयुर्विज्ञान संस्थान, नई दिल्ली
All India Institute Of Medical Sciences, New Delhi

Dr. Savita Yadav

Prof. Savita Yadav

Research Interests

Proteomics, Biomarker discovery and Functional Biophysics-

(i) for early detection of diseases, specifically, gynaecological cancers.

(ii) to gain molecular insights into pathogenesis of idiopathic male infertility. 

 

Fellowships and Membership of Scientific bodies

Fellow: National Academy of Medical Sciences, India

              Indian Academy of Biomedical Sciences, India

                                   

Member: Indian society for study of reproduction and fertility, Proteomics Society of India, National Academy of Science India, Indian Science Congress Association, Indian Biophysical Society.

 

Email

This email address is being protected from spambots. You need JavaScript enabled to view it. ; This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Contact Number

+91-11-26594608; +91-11-26546445

Awards and Honors

  • SERB-POWER Fellowship 2021
  • AIIMS research excellence Award in Oncology under Basic Science category 2019
  • Prof. S. S. Guraya Memorial Oration, ISSRF 2018
  • Hari-Om-Trust memorial award of ICAR, 2017
  • Innovation award in diagnostic category at IKMC, 2016
  • G.P. Talwar award for Mid-Career Scientist, ISSRF 2015
  • AIIMS Research excellence award, 2013
  • AIIMS Research excellence award, 2012
  • ISCA Young Scientist award, 1991

Recent Publications

 

  1. Naglot S, Tomar AK, Singh N, Yadav S. (2021) Label-free proteomics of spermatozoa identifies candidate protein markers of idiopathic recurrent pregnancy loss. Reprod Biol 21(3):100539.
  2. Saini A, Chandra KB, Kumar V, Mathur SR, Sharma JB, Kumar S, Yadav S. (2020) Analysis of Multimerin 1 (MMRN1) expression in ovarian cancer. Mol Biol Rep., 47(12):9459-9468.
  3. Jain P, Ojha SK, Kumar V, Bakhshi S, Singh S, Yadav S. Differential seminal plasma proteome signatures of acute lymphoblastic leukemia survivors. Reprod Biol. 2019 Nov 8. doi: 10.1016/j.repbio.2019.11.002.
  4. Kant K, Tomar AK, Sharma P, Kundu B, Singh S, Yadav S. Human Epididymis Protein 4 Quantification and Interaction Network Analysis in Seminal Plasma. Protein Pept Lett. 2019 26(6):458-465.
  5. Kant K, Tomar AK, Singh S, Yadav S. Ageing associated proteomic variations in seminal plasma of Indian men. J Proteins Proteom. 2019; 10(2): 83-89.
  6. Kumari N, Yadav S. Modulation of protein oligomerization: An overview. Prog Biophys Mol Biol. 2019 149:99-113.
  7. M K MA, Kumaresan A, Yadav S, Mohanty TK, Datta TK. Comparative proteomic analysis of high- and low-fertile buffalo bull spermatozoa for identification of fertility-associated proteins. Reprod Domest Anim. 2019 54(5):786-794.
  8. Sinha A, Singh V, Singh S, Yadav S. Proteomic analyses reveal lower expression of TEX40 and ATP6V0A2 proteins related to calcium ion entry and acrosomal acidification in asthenozoospermic males. Life Sci. 2018 218:81-88.
  9. Muhammad Aslam MK, Sharma VK, Pandey S, Kumaresan A, Srinivasan A, Datta TK, Mohanty TK, Yadav S. Identification of biomarker candidates for fertility in spermatozoa of crossbred bulls through comparative proteomics. Theriogenology. 2018 119:43-51.
  10. Tajmul M, Parween F, Singh L, Mathur SR, Sharma JB, Kumar S, Sharma DN, Yadav S, Identification and validation of salivary proteomic signatures for non-invasive detection of ovarian cancer. Int J Biol Macromol. 2017 108:503-514.
  11. Kumar S, Sharma VK, Yadav S, Dey S, Antiproliferative and apoptotic effects of black turtle bean extracts on human breast cancer cell line through extrinsic and intrinsic pathway. Chem Cent J. 2017 11(1):56
  12. Kumari N, Chaturvedi SK, Khan R, Sharma A, Khan RH, Yadav S, Characterization of CNL like protein fragment (CNL-LPF) from mature Lageneria siceraria seeds. Int J Biol Macromol. 2017 104(Pt A):1194-1203
  13. Sharma V, Gupta N, Srivastava N, Rana V, Chandna P, Yadav S, Sharma A, Diagnostic potential of inflammatory biomarkers in early childhood caries - A case control study. Clin Chim Acta. 2017 471:158-163
  14. Kumar V, Tomar AK, Sahu V, Dey S, Yadav S, Structural insights of Mycobacterium GTPase-Obg and anti-sigma-F factor Usfx interaction. J Mol Recognit. 2017 30(10).
  15. Sinha A, Singh V, Yadav S. Multi-omics and male infertility: status, integration and future prospects. Front Biosci (Schol Ed). 2017 9:375-394.
  16. Rajak SK, Kumaresan A, Attupuram NM, Chhillar S, Baithalu RK, Nayak S, Sreela L, Singh RK, Tripathi UK, Mohanty TK, Yadav S Age-related changes in transcriptional abundance and circulating levels of anti-Mullerian hormone and Sertoli cell count in crossbred and Zebu bovine males. Theriogenology. 2017 89:1-8.
  17. Saraswat M, Joenväärä S, Jain T, Tomar AK, Sinha A, Singh S, Yadav S, Renkonen R.Human Spermatozoa Quantitative Proteomic Signature Classifies Normo- and Asthenozoospermia. Mol Cell Proteomics. 2017 16(1):57-72
  18. Sharma VK, Singh A, Srivastava SK, Kumar V, Gardi NL, Nalwa A, Dinda AK, Chattopadhyay P, Yadav S, Increased expression of platelet-derived growth factor associated protein-1 is associated with PDGF-B mediated glioma progression. Int J Biochem Cell Biol. 2016 78:194-205.
  19. Kumar V, Singh HN, Tomar AK, Dantham S, Yadav S, Searching new targets to counter drug resistance - GTPase-Obg mRNA expression analysis in Mycobacterium under stress and in silico docking with GTPase inhibitors. J Biomol Struct Dyn. 2016 12:1-9
  20. Kumari N, Kumar R, Mishra V, Yadav S, Polyclonal Antibody Development Against Purified CC-NBS-LRR like Protein Fragment from Mature Lageneria siceraria Seeds and Immunolocalization. Protein J. 2016 35(5):379-390.
  21. Saraswat M, Joenväärä S, Tomar AK, Singh S, Yadav S, Renkonen R. N-Glycoproteomics of Human Seminal Plasma Glycoproteins. J Proteome Res. 2016 15(3):991-1001.
  22. Yadav VK, Mandal RS, Puniya BL, Singh S, Yadav S. Studies on the interactions of SAP-1 (an N-terminal truncated form of cystatin S) with its binding partners by CD-spectroscopic and molecular docking methods. J Biomol Struct Dyn. 2015 33(1):147-57.
  23. Muhammad Aslam MK, Kumaresan A, Rajak SK, Tajmul M, Datta TK, Mohanty TK, Srinivasan A, Yadav S. Comparative proteomic analysis of Taurine, Indicine, and crossbred (Bos taurus × Bos indicus) bull spermatozoa for identification of proteins related to sperm malfunctions and subfertility in crossbred bulls. Theriogenology. 2015 84(4):624-33.
  24. Tripathi UK, Chhillar S, Kumaresan A, Aslam MK, Rajak SK, Nayak S, Manimaran A, Mohanty TK, Yadav S. Morphometric evaluation of seminiferous tubule and proportionate numerical analysis of Sertoli and spermatogenic cells indicate differences between crossbred and purebred bulls. Vet World. 2015 8(5):645-50.
  25. Kumari N, Tajmul M, Yadav S. Proteomic analysis of mature Lagenaria siceraria seed. Appl Biochem Biotechnol. 2015 175(8):3643-56.
  26. Yadav VK, Mandal RS, Puniya BL, Kumar R, Dey S, Singh S, Yadav S. Structural and binding studies of SAP-1 protein with heparin. Chem Biol Drug Des. 2015 85(3):404-10.

 

 

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