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Controversial Issues in EC Introduction : A Debate
Is Medical Supervision a must for Medical Abortion?

FOR THE MOTIONAGAINST THE MOTION
– Dr Rekha G. Daver GMC, Mumbai – Dr Vinita Das, KGMC, Lucknow

There is no debate about the fact that every abortion needs medical supervision– pontaneous or induced andmedical or surgical abortion.

Can women use medical abortion without medical supervision?

Medical abortion offers a new option to women seeking to terminate their pregnancies, in particular mifepristone-misoprostol combination consists of simple pills and it is potentially suitable for self administration. Yet access to and administration of this method of abortion remains tightly controlled.

In this, strict control is medically necessary. This is to identify the seven steps that women would need to accomplish in order to use this mifepristone – misoprostol regime without medical supervision.

Which are the seven steps, women would be incapable of controlling if such pills are given to her without medical supervision?

1. Recognize that they are pregnant (Delayed menses,lactational amenorrhoea, ectopic pregnancy, intrauterine pregnancy, irregular menses, gestation not known, etc have to be ruled out).
2. Estimate the duration of pregnancy to be sufficiently short so that she is an ideal case for a particular method.
3. Select mifepristone – misoprostol regime appropriately (rule out corticosteroid therapy, contraindication to PGs, previous cesarean)
4. Adhere to the correct protocol
5. Manage adverse reactions and seek care for those that warrant medical attention.
6. Possibly, notice and cope with expulsion of embryo.
7. Recognize complete abortion

As evident not only women from developing countries but also from developed countries need medical supervision, as they are incapable of controlling these 7 steps. There the several other advantages of having medical supervision. Thorough check-up can be done and contraceptive advice can be given in the same sitting. Patients can be counseled to use some other regular method of contraception.

You also examine her, thus any co-existing problem can be identified and treated simultaneously.

Medical Methods of early abortion differ from surgical methods, in that women, themselves, can potentially administer the regimens. As currently researched and offered, however, the main regimen used for medical abortion, mifepristone - misoprostol is highly medicalized, involving several clinic visits and extensive physician involvement. Other drugs in use are methotrexate, tamoxifen, gemeprost etc.

In scientific terms, medical supervision is a preventive strategy and not a treatment. Its aim is to detect complications early and have proper selection of the client. The recommended medical supervision for medical abortion, at present, is a three-visit clinic-based administration of drug. The aim is to detect the complications and problems early.

Evidence suggests that most women can handle most steps of the medical abortion process themselves, effectively and safely. The utility of clinic visits to ingest mifepristone and misoprostol is questionable. For many women, even the follow-up visits could, perhaps, be replaced by telephone follow-up, combined with home pregnancy tests.

Visible complications of medical abortion that can be detected by the patient herself if known to her, include pain, headache, gastro-intestinal symptoms, bleeding, incomplete abortion, severe hemorrhage (< 1%) and failure (< 1%). The patient can go to the doctor and seek advice.

Invisible complications can be missed ectopic or a congenital malformation in case of a continuing pregnancy. These can hardly be detected by medical supervision. Ectopic pregnancy is seen in 0.1% of cases, and can be diagnosed by per vaginal examination in a symptomatic patient in 10% cases only. Therefore, to detect only 1 case of ectopic pregnancy by medicalsupervision, 10,000 women will be kept under supervision.

Also, the incidence of failure or incomplete abortion rate is not reduced by medical supervision. The client has to visit the doctor for surgical abortion in both the cases.

The success of medical abortion depends on the regimen used, dosage schedule, route of administration and gestational age.

Life-threatening complications (severe haemorrhage) are seen in < 1% of patients, but they cannot be prevented by medical supervision. Life can only be saved if patient goes to the doctor or hospital for management. Haemorrhage can occur at any time. Therefore, the recommended three-visit supervision is not enough. It needs hospitalization for 2 weeks or a minimum of 3 days, which is neither cost-effective nor convenient. Clinic visits, especially in less-developed countries where women can ill afford time lost from work or childcare and associated transport costs, are
burdensome and inconvenient, and should be eliminated, if not needed, to safeguard women’s health.

Clinic visits also compromise privacy which is essential in places where abortion is stigmatized. Substantial clinician involvement in the abortion process, if not warranted medically, is wasteful in countries where medical attention is scarce, physician skills and attention spread is thin, and clinics overburdened.

Patients undergoing medical abortion require only a partial medical supervision. It includes first visit at registration for proper client-selection, to rule out ectopic gestation, explain the risk of complications and failure rate and congenital malformation and establish proper linkage in case of emergency. What is needed is:

• An educated and well-informed client
• Good initial guidelines in regional language and product-insert with the drug
• Identified back-up emergency access facilities and their telephone numbers

MTP Act has to be modified to take full benefit of medical abortion and to resolve social, legal and ethical issues.


EXPERT COMMENTS
– Dr Batya Elul, Population council

Liberalized use of home administration of misoprostol has several advantages.

Over two-third of women in our setting (USA, Vienna) when offered an option, chose to take misoprostol at home. Such women had higher efficacy rates than those who took misoprostol at clinic. This is because doctors over intervened.

Home administration is not attributed to unsafe use, it is a good option for some women, but patients at home may forget to take misoprostol in time. Severe adverse events related to medical abortion are rare.

The last thing we have to be concerned about misoprostol administration at home is incomplete abortion. We need to be liberal in setting guidelines and think towards the future and set standards that offer options so that more and more people can use this method. But this does not mean sale over the country. Since initial assessment for suitability of client is a must and women need to be appropriately counselled about the side-effects and complications and when and where to report in case of a problem.

 

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Introduction | Overview of the Consortium
Current Status of Medical Abortion | Consensus Issues & Recommendations
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